RU95100759A - Эндопаразитицидное средство - Google Patents
Эндопаразитицидное средствоInfo
- Publication number
- RU95100759A RU95100759A RU95100759/13A RU95100759A RU95100759A RU 95100759 A RU95100759 A RU 95100759A RU 95100759/13 A RU95100759/13 A RU 95100759/13A RU 95100759 A RU95100759 A RU 95100759A RU 95100759 A RU95100759 A RU 95100759A
- Authority
- RU
- Russia
- Prior art keywords
- agent
- cyclohexylcarbonyl
- benzazepine
- derivative
- cyclic depsipeptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Luminescent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Предлагается эндопаразитицидное средство, содержащее циклический депсипептид, состоящий из аминокислот и гидроксикарбоновых кислот в качестве кольцевых звеньев и 6 - 30 кольцевых атомов, или его оптический изомер, или рацемат, и дополнительно 2-(циклогексилкарбонил) -1,2,3,6,7,11b-гексагидро- 4H -пиразино[2,1-a]изохинолин-4-он или 2-(циклогексилкарбонил)- 2,3,6,7,8,12b-гексагидропиразино[2,1-a] [2] -бензазепин-4(1H)-он. При этом циклический депсипептид и указанное производное изохинолинона или же производное бензазепина предпочтительно взяты в массовом соотношении от 1 : 1 до 10 : 1.
Claims (1)
- Предлагается эндопаразитицидное средство, содержащее циклический депсипептид, состоящий из аминокислот и гидроксикарбоновых кислот в качестве кольцевых звеньев и 6 - 30 кольцевых атомов, или его оптический изомер, или рацемат, и дополнительно 2-(циклогексилкарбонил) -1,2,3,6,7,11b-гексагидро- 4H -пиразино[2,1-a]изохинолин-4-он или 2-(циклогексилкарбонил)- 2,3,6,7,8,12b-гексагидропиразино[2,1-a] [2] -бензазепин-4(1H)-он. При этом циклический депсипептид и указанное производное изохинолинона или же производное бензазепина предпочтительно взяты в массовом соотношении от 1 : 1 до 10 : 1.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4400464A DE4400464A1 (de) | 1994-01-11 | 1994-01-11 | Endoparasitizide Mittel |
| DEP4400464.8 | 1994-01-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU95100759A true RU95100759A (ru) | 1997-03-20 |
| RU2124364C1 RU2124364C1 (ru) | 1999-01-10 |
Family
ID=6507651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU95100759/13A RU2124364C1 (ru) | 1994-01-11 | 1995-01-11 | Эндопаразитицидное средство |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5589503A (ru) |
| EP (1) | EP0662326B1 (ru) |
| JP (2) | JP4033920B2 (ru) |
| KR (1) | KR100359618B1 (ru) |
| CN (1) | CN1165338C (ru) |
| AT (1) | ATE209501T1 (ru) |
| AU (1) | AU685535B2 (ru) |
| CA (1) | CA2139725C (ru) |
| CZ (1) | CZ290246B6 (ru) |
| DE (3) | DE4400464A1 (ru) |
| DK (1) | DK0662326T5 (ru) |
| ES (1) | ES2168285T3 (ru) |
| FI (1) | FI116885B (ru) |
| FR (1) | FR06C0002I2 (ru) |
| HU (1) | HU226207B1 (ru) |
| IL (1) | IL112285A (ru) |
| NL (1) | NL300218I2 (ru) |
| NO (2) | NO307030B1 (ru) |
| NZ (1) | NZ270300A (ru) |
| PH (1) | PH31462A (ru) |
| PL (1) | PL180019B1 (ru) |
| PT (1) | PT662326E (ru) |
| RU (1) | RU2124364C1 (ru) |
| SK (1) | SK283367B6 (ru) |
| TW (1) | TW364850B (ru) |
| UA (1) | UA41327C2 (ru) |
| ZA (1) | ZA95136B (ru) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317458A1 (de) * | 1992-06-11 | 1993-12-16 | Bayer Ag | Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung |
| DE19520275A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasitizide Mittel |
| CA2306883C (en) * | 1997-10-20 | 2007-11-27 | Dainippon Pharmaceutical Co., Ltd. | Fast-dissolving pharmaceutical composition comprising as-3201 |
| DE19921887A1 (de) * | 1999-05-12 | 2000-11-16 | Bayer Ag | Endoparasitizide Mittel |
| DE10008128A1 (de) * | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| KR100358084B1 (ko) * | 2000-10-04 | 2002-10-25 | 주식회사대성미생물연구소 | 프라지콴텔과 시메티딘 합제를 이용한 어류의아가미흡충증 치료방법 |
| DE10104362A1 (de) * | 2001-02-01 | 2002-08-08 | Bayer Ag | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| KR20040012990A (ko) * | 2001-06-28 | 2004-02-11 | 제온 코포레이션 | 시클로알킬 알킬 에테르 화합물을 함유하여 이루어지는용제 및 시클로알킬 알킬 에테르 화합물의 제조방법 |
| EP1450860B1 (en) * | 2001-10-05 | 2013-09-18 | Rubicon Scientific LLC | Animal feeds including actives |
| DE10358525A1 (de) * | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
| DE10359798A1 (de) | 2003-12-19 | 2005-07-21 | Bayer Healthcare Ag | Cyclohexadepsipeptide zur Bekämpfung von Endoparasiten und ein Verfahren zu ihrer Herstellung |
| DE102004055316A1 (de) * | 2004-11-16 | 2006-05-18 | Bayer Healthcare Ag | Verhinderung vertikaler Endoparasiten-Infektionen |
| DE102005011779A1 (de) * | 2005-03-11 | 2006-09-14 | Bayer Healthcare Ag | Endoparasitizide Mittel |
| CN102149717B (zh) * | 2008-08-28 | 2014-05-14 | 辉瑞大药厂 | 二氧杂-双环[3.2.1]辛烷-2，3，4-三醇衍生物 |
| DE102009012423A1 (de) | 2009-03-10 | 2010-09-16 | Bayer Animal Health Gmbh | Zubereitung auf Ölbasis |
| UA114287C2 (uk) * | 2011-03-02 | 2017-05-25 | Дзе Юніверсіті Оф Токіо | Засіб для боротьби з ендопаразитами |
| SI2782565T1 (sl) * | 2011-11-25 | 2019-12-31 | Bayer Intellectual Property Gmbh | Uporaba aril in hetaril karboksamidov kot endoparaziticid |
| PL3298027T3 (pl) | 2015-05-20 | 2021-11-08 | Boehringer Ingelheim Animal Health USA Inc. | Przeciwrobacze związki depsipeptydów |
| AU2016380868B2 (en) | 2015-12-28 | 2019-11-28 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| US11382949B2 (en) | 2016-11-16 | 2022-07-12 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| CA3147171A1 (en) | 2019-08-14 | 2021-02-18 | Vetoquinol Sa | Compositions comprising tigolaner for controlling parasites |
| CN113943350B (zh) * | 2021-11-02 | 2023-08-15 | 海南大学三亚南繁研究院 | 一种环肽化合物或其药学上可接受的盐及其制备方法和应用、药物及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) * | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| GB9024924D0 (en) * | 1990-11-16 | 1991-01-02 | Beecham Group Plc | Novel compositions |
| NZ247278A (en) * | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
| DK0634408T3 (da) * | 1992-03-17 | 2002-04-22 | Fujisawa Pharmaceutical Co | Depsipeptidderivater, fremstilling og anvendelse deraf |
| DE4317458A1 (de) * | 1992-06-11 | 1993-12-16 | Bayer Ag | Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung |
| CN1073560C (zh) * | 1993-02-19 | 2001-10-24 | 明治制果株式会社 | 环缩酚酸肽pf1022衍生物 |
| DE4317457A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4317432A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
-
1994
- 1994-01-11 DE DE4400464A patent/DE4400464A1/de not_active Withdrawn
- 1994-12-16 TW TW083111751A patent/TW364850B/zh not_active IP Right Cessation
- 1994-12-20 AU AU81592/94A patent/AU685535B2/en not_active Expired
- 1994-12-27 EP EP94120772A patent/EP0662326B1/de not_active Expired - Lifetime
- 1994-12-27 PT PT94120772T patent/PT662326E/pt unknown
- 1994-12-27 DE DE59409977T patent/DE59409977D1/de not_active Expired - Lifetime
- 1994-12-27 AT AT94120772T patent/ATE209501T1/de active
- 1994-12-27 ES ES94120772T patent/ES2168285T3/es not_active Expired - Lifetime
- 1994-12-27 DE DE1994509977 patent/DE122006000001I2/de active Active
- 1994-12-27 DK DK94120772T patent/DK0662326T5/da active
-
1995
- 1995-01-04 US US08/368,515 patent/US5589503A/en not_active Expired - Lifetime
- 1995-01-06 NZ NZ270300A patent/NZ270300A/en not_active IP Right Cessation
- 1995-01-06 CA CA002139725A patent/CA2139725C/en not_active Expired - Lifetime
- 1995-01-09 KR KR1019950000274A patent/KR100359618B1/ko not_active IP Right Cessation
- 1995-01-09 PH PH49754A patent/PH31462A/en unknown
- 1995-01-09 JP JP01633595A patent/JP4033920B2/ja not_active Expired - Lifetime
- 1995-01-09 FI FI950091A patent/FI116885B/fi not_active IP Right Cessation
- 1995-01-09 PL PL95306709A patent/PL180019B1/pl unknown
- 1995-01-09 IL IL11228595A patent/IL112285A/xx not_active IP Right Cessation
- 1995-01-10 UA UA95018024A patent/UA41327C2/ru unknown
- 1995-01-10 NO NO950093A patent/NO307030B1/no not_active IP Right Cessation
- 1995-01-10 CZ CZ199561A patent/CZ290246B6/cs not_active IP Right Cessation
- 1995-01-10 ZA ZA95136A patent/ZA95136B/xx unknown
- 1995-01-10 SK SK31-95A patent/SK283367B6/sk not_active IP Right Cessation
- 1995-01-10 HU HU9500065A patent/HU226207B1/hu active Protection Beyond IP Right Term
- 1995-01-11 CN CNB951011588A patent/CN1165338C/zh not_active Expired - Lifetime
- 1995-01-11 RU RU95100759/13A patent/RU2124364C1/ru active Protection Beyond IP Right Term
-
2006
- 2006-01-26 NL NL300218C patent/NL300218I2/nl unknown
- 2006-01-26 FR FR06C0002C patent/FR06C0002I2/fr active Active
- 2006-01-27 NO NO2006001C patent/NO2006001I2/no unknown
-
2007
- 2007-09-04 JP JP2007228858A patent/JP2007314580A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ND4A | Extension of patent duration | ||
| PC4A | Invention patent assignment |
Effective date: 20070410 |
|
| HK4A | Changes in a published invention | ||
| PC4A | Invention patent assignment |
Effective date: 20091009 |
|
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20130207 |