DE69718177T2 - Substituierte pyrimidinderivate und ihre pharmazeutische anwendung - Google Patents
Substituierte pyrimidinderivate und ihre pharmazeutische anwendungInfo
- Publication number
- DE69718177T2 DE69718177T2 DE69718177T DE69718177T DE69718177T2 DE 69718177 T2 DE69718177 T2 DE 69718177T2 DE 69718177 T DE69718177 T DE 69718177T DE 69718177 T DE69718177 T DE 69718177T DE 69718177 T2 DE69718177 T2 DE 69718177T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- heterocyclic derivatives
- date feb
- sec
- pharmaceutical application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9617060.0A GB9617060D0 (en) | 1996-08-14 | 1996-08-14 | Chemical compounds |
GBGB9703027.4A GB9703027D0 (en) | 1997-02-14 | 1997-02-14 | Chemical compounds |
PCT/GB1997/002029 WO1998006705A1 (en) | 1996-08-14 | 1997-07-25 | Substituted pyrimidine derivatives and their pharmaceutical use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69718177D1 DE69718177D1 (de) | 2003-02-06 |
DE69718177T2 true DE69718177T2 (de) | 2003-10-23 |
Family
ID=26309870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69718177T Expired - Fee Related DE69718177T2 (de) | 1996-08-14 | 1997-07-25 | Substituierte pyrimidinderivate und ihre pharmazeutische anwendung |
Country Status (18)
Country | Link |
---|---|
US (1) | US6093718A (de) |
EP (1) | EP0925286B1 (de) |
JP (1) | JP2000516602A (de) |
KR (1) | KR20000029984A (de) |
CN (1) | CN1228087A (de) |
AT (1) | ATE230399T1 (de) |
AU (1) | AU3701797A (de) |
BG (1) | BG103190A (de) |
BR (1) | BR9711135A (de) |
CA (1) | CA2260872A1 (de) |
CZ (1) | CZ45699A3 (de) |
DE (1) | DE69718177T2 (de) |
IL (1) | IL128428A0 (de) |
NO (1) | NO990663L (de) |
PL (1) | PL331599A1 (de) |
SK (1) | SK18499A3 (de) |
TR (1) | TR199900303T2 (de) |
WO (1) | WO1998006705A1 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
AU1608397A (en) | 1996-02-02 | 1997-08-22 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
GB9602166D0 (en) | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
CN1228087A (zh) * | 1996-08-14 | 1999-09-08 | 曾尼卡有限公司 | 取代的嘧啶衍生物和它们的药物用途 |
UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
ATE242774T1 (de) | 1997-02-13 | 2003-06-15 | Astrazeneca Ab | Heterozyklische verbindungen die als oxido- squalen-zyklase-inhibitoren anwendung finden |
WO1998035956A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
US7115632B1 (en) | 1999-05-12 | 2006-10-03 | G. D. Searle & Co. | Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
US6794511B2 (en) | 1997-03-04 | 2004-09-21 | G. D. Searle | Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
US6696449B2 (en) | 1997-03-04 | 2004-02-24 | Pharmacia Corporation | Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors |
GB9715892D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
AU9280698A (en) * | 1997-09-30 | 1999-04-23 | Daiichi Pharmaceutical Co., Ltd. | Sulfonyl derivatives |
HUP0101810A3 (en) * | 1998-01-27 | 2002-05-28 | Aventis Pharm Prod Inc | Substituted oxoazaheterocyclyl factor xa inhibitors and pharmaceutical compositions containing them |
AU5196399A (en) * | 1998-08-11 | 2000-03-06 | Daiichi Pharmaceutical Co., Ltd. | Novel sulfonyl derivatives |
GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
CA2373500A1 (en) * | 1999-05-12 | 2000-11-23 | G.D. Searle & Co. | Hydroxamic acid derivatives as matrix metalloprotease inhibitors |
TWI288745B (en) | 2000-04-05 | 2007-10-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
WO2003000657A1 (fr) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Derives de diamine |
WO2003037338A2 (en) * | 2001-11-01 | 2003-05-08 | Vertex Pharmaceuticals Incorporated | Modulators of the cholesterol biosynthetic pathway |
RU2005136368A (ru) * | 2003-04-23 | 2006-06-10 | Глэксо Груп Лимитед (GB) | Производные пиперазина и их применение для лечения неврологических и психиатрических заболеваний |
CA2572075A1 (en) * | 2004-06-28 | 2006-01-12 | Janssen Pharmaceutica Nv | Hetero isonipecotic modulators of vanilloid vr1 receptor |
DE602005005080T2 (de) * | 2004-10-15 | 2009-02-26 | Glaxo Group Ltd., Greenford | Pyrrolidinderivate als histaminrezeptor-liganden |
WO2007003964A1 (en) * | 2005-06-30 | 2007-01-11 | Prosidion Limited | G-protein coupled receptor agonists |
AR059898A1 (es) * | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
KR101171507B1 (ko) * | 2007-08-13 | 2012-08-07 | 에프. 호프만-라 로슈 아게 | 신규 피페라진 아마이드 유도체 |
KR101533440B1 (ko) * | 2007-09-14 | 2015-07-03 | 얀센 파마슈티칼스 인코포레이티드 | 1´,3´-이치환된-4-페닐-3,4,5,6-테트라히드로-2h,1´h-[1,4´]비피리디닐-2´-온 |
BRPI0817101A2 (pt) | 2007-09-14 | 2017-05-09 | Addex Pharmaceuticals Sa | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-dissubstituídas |
US8722894B2 (en) * | 2007-09-14 | 2014-05-13 | Janssen Pharmaceuticals, Inc. | 1,3-disubstituted-4-phenyl-1H-pyridin-2-ones |
AU2008323287B2 (en) * | 2007-11-14 | 2011-07-14 | Addex Pharma S.A. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
WO2009079547A1 (en) * | 2007-12-18 | 2009-06-25 | Smithkline Beecham (Cork) Limited | Quinazoline anhydrate forms |
CA2731897C (en) * | 2008-08-06 | 2013-07-02 | Pfizer Limited | Diazepine and diazocane compounds as mc4 agonists |
ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
GB0818241D0 (en) | 2008-10-06 | 2008-11-12 | Cancer Res Technology | Compounds and their use |
US8697689B2 (en) | 2008-10-16 | 2014-04-15 | Janssen Pharmaceuticals, Inc. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
EA020671B1 (ru) | 2009-05-12 | 2014-12-30 | Янссен Фармасьютикалз, Инк. | ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 |
MY161325A (en) | 2009-05-12 | 2017-04-14 | Janssen Pharmaceuticals Inc | 1, 2, 4-triazolo[4,3-a]pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
JP5852666B2 (ja) | 2010-11-08 | 2016-02-03 | ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド | 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用 |
PT2649069E (pt) | 2010-11-08 | 2015-11-20 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina e sua utilização como moduladores alostéricos positivos de recetores mglur2 |
CA2814998C (en) | 2010-11-08 | 2019-10-29 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
KR20220039824A (ko) | 2014-01-21 | 2022-03-29 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
IL279202B2 (en) | 2014-01-21 | 2023-09-01 | Janssen Pharmaceutica Nv | Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT340933B (de) * | 1973-08-20 | 1978-01-10 | Thomae Gmbh Dr K | Verfahren zur herstellung neuer pyrimidinderivate und ihrer saureadditionssalze |
US4167567A (en) * | 1978-05-05 | 1979-09-11 | The Upjohn Company | Antihypertensive 4-aminoquinolines |
US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
SE8203887D0 (sv) * | 1982-06-23 | 1982-06-23 | Kabivitrum Ab | Nya trombininhiberande foreningar |
GB8601160D0 (en) * | 1986-01-17 | 1986-02-19 | Fujisawa Pharmaceutical Co | Heterocyclic compounds |
GB8603120D0 (en) * | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
GB8609630D0 (en) * | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
JPH0696575B2 (ja) * | 1987-09-17 | 1994-11-30 | 三菱化成株式会社 | 4−アミノピリジン誘導体及びその酸付加塩 |
US4871721A (en) * | 1988-01-11 | 1989-10-03 | E. R. Squibb & Sons, Inc. | Phosphorus-containing squalene synthetase inhibitors |
GB8817315D0 (en) * | 1988-07-20 | 1988-08-24 | Pfizer Ltd | Triazole antifungal agents |
GB8819307D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Antiarrhythmic agents |
DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
EP0511347A1 (de) * | 1990-11-15 | 1992-11-04 | Pentapharm A.G. | Meta-substituierte phenylalanin-derivate |
EP0495750A3 (en) * | 1991-01-14 | 1992-09-16 | Ciba-Geigy Ag | Heterocyclic hydroxylamine |
IT1245712B (it) * | 1991-04-09 | 1994-10-14 | Boehringer Mannheim Italia | Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree |
FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
EP0519449A1 (de) * | 1991-06-21 | 1992-12-23 | Boehringer Mannheim Italia S.P.A. | 2-Amino-4-aryl-Thiazolderivate mit asthmahemmender und entzündungshemmender Wirkung auf die Atemwegen |
AU2573592A (en) * | 1991-09-19 | 1993-04-27 | Smithkline Beecham Corporation | Pyridine compounds for treating leukotriene-related diseases |
PH31294A (en) * | 1992-02-13 | 1998-07-06 | Thomae Gmbh Dr K | Benzimidazolyl derivatives, pharmaceutical compositions containing these compounds and process for preparing them. |
HU211995B (en) * | 1992-06-30 | 1996-01-29 | Gyogyszerkutato Intezet | Process to prepare novel benzoyl amino acid derivs. and pharmaceutical compns. contg.them |
US5371091A (en) * | 1992-08-31 | 1994-12-06 | Bristol-Myers Squibb Company | Heteroaromatic amine thrombin inhibitors |
FR2697252B1 (fr) * | 1992-10-28 | 1994-12-09 | Fournier Ind & Sante | Dérivés de 1,2,3,5,6,7,8,8a-octahydro-5,5,8a-triméthyl-(8abeta)-6-isoquinolineamine, leur procédé de préparation et leur utilisation en thérapeutique. |
DE4243858A1 (de) * | 1992-12-23 | 1994-06-30 | Thomae Gmbh Dr K | Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US5332822A (en) * | 1992-12-24 | 1994-07-26 | Bristol-Myers Squibb Company | Heteroaromatic and thioheteroaromatic substituted sulfonamide thrombin inhibitors |
DE4302485A1 (de) * | 1993-01-29 | 1994-08-04 | Merck Patent Gmbh | Piperazinderivate |
JPH07509731A (ja) * | 1993-02-10 | 1995-10-26 | ペンタファルム アクチェンゲゼルシャフト | トロンビン阻害剤としての置換されたフェニルアラニン誘導体のピペラジド |
TW257757B (de) * | 1993-03-03 | 1995-09-21 | Boehringer Mannheim Gmbh | |
DE4306506A1 (de) * | 1993-03-03 | 1994-09-08 | Boehringer Mannheim Gmbh | Neue 4-Alkylaminopyridine - Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
DE4306873A1 (de) * | 1993-03-05 | 1994-09-08 | Boehringer Mannheim Gmbh | Neue 4-Aminopyridine-Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
EP0690847A1 (de) * | 1993-03-29 | 1996-01-10 | Zeneca Limited | Heterozyklische derivate als plätchenaggregationsinhibitoren |
AU3107795A (en) * | 1994-08-09 | 1996-03-07 | Pentapharm Ag | Inhibitors of the benzamidine type |
IL115420A0 (en) * | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
EP0785939A1 (de) * | 1994-10-11 | 1997-07-30 | Takeda Chemical Industries, Ltd. | Substituierte heterobicyclische alkylamine und ihre verwendung als squalenoxidcyclase-inhibitoren |
IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
US5856326A (en) * | 1995-03-29 | 1999-01-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
IL117580A0 (en) * | 1995-03-29 | 1996-07-23 | Merck & Co Inc | Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them |
GB9516709D0 (en) * | 1995-08-15 | 1995-10-18 | Zeneca Ltd | Medicament |
AU1608397A (en) * | 1996-02-02 | 1997-08-22 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
DK0892780T3 (da) * | 1996-02-22 | 2003-03-03 | Bristol Myers Squibb Pharma Co | m-Amidinophenylanaloger som faktor Xa-inhibitorer |
CN1228087A (zh) * | 1996-08-14 | 1999-09-08 | 曾尼卡有限公司 | 取代的嘧啶衍生物和它们的药物用途 |
-
1997
- 1997-07-25 CN CN97197282A patent/CN1228087A/zh active Pending
- 1997-07-25 CZ CZ99456A patent/CZ45699A3/cs unknown
- 1997-07-25 AU AU37017/97A patent/AU3701797A/en not_active Abandoned
- 1997-07-25 DE DE69718177T patent/DE69718177T2/de not_active Expired - Fee Related
- 1997-07-25 JP JP10509469A patent/JP2000516602A/ja not_active Ceased
- 1997-07-25 WO PCT/GB1997/002029 patent/WO1998006705A1/en active IP Right Grant
- 1997-07-25 SK SK184-99A patent/SK18499A3/sk unknown
- 1997-07-25 BR BR9711135A patent/BR9711135A/pt not_active Application Discontinuation
- 1997-07-25 KR KR1019997001247A patent/KR20000029984A/ko not_active Application Discontinuation
- 1997-07-25 US US09/242,309 patent/US6093718A/en not_active Expired - Fee Related
- 1997-07-25 IL IL12842897A patent/IL128428A0/xx unknown
- 1997-07-25 TR TR1999/00303T patent/TR199900303T2/xx unknown
- 1997-07-25 CA CA002260872A patent/CA2260872A1/en not_active Abandoned
- 1997-07-25 EP EP97933774A patent/EP0925286B1/de not_active Expired - Lifetime
- 1997-07-25 PL PL97331599A patent/PL331599A1/xx unknown
- 1997-07-25 AT AT97933774T patent/ATE230399T1/de not_active IP Right Cessation
-
1999
- 1999-02-12 NO NO990663A patent/NO990663L/no not_active Application Discontinuation
- 1999-02-22 BG BG103190A patent/BG103190A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR20000029984A (ko) | 2000-05-25 |
EP0925286B1 (de) | 2003-01-02 |
EP0925286A1 (de) | 1999-06-30 |
TR199900303T2 (xx) | 1999-06-21 |
ATE230399T1 (de) | 2003-01-15 |
JP2000516602A (ja) | 2000-12-12 |
CA2260872A1 (en) | 1998-02-19 |
NO990663D0 (no) | 1999-02-12 |
US6093718A (en) | 2000-07-25 |
PL331599A1 (en) | 1999-08-02 |
NO990663L (no) | 1999-04-12 |
WO1998006705A1 (en) | 1998-02-19 |
AU3701797A (en) | 1998-03-06 |
IL128428A0 (en) | 2000-01-31 |
DE69718177D1 (de) | 2003-02-06 |
CN1228087A (zh) | 1999-09-08 |
BR9711135A (pt) | 1999-08-17 |
SK18499A3 (en) | 1999-07-12 |
CZ45699A3 (cs) | 1999-05-12 |
BG103190A (en) | 1999-11-30 |
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