RU93004678A - Противомикробные производные карбапенема, способы их получения и применение - Google Patents
Противомикробные производные карбапенема, способы их получения и применениеInfo
- Publication number
- RU93004678A RU93004678A RU93004678/04A RU93004678A RU93004678A RU 93004678 A RU93004678 A RU 93004678A RU 93004678/04 A RU93004678/04 A RU 93004678/04A RU 93004678 A RU93004678 A RU 93004678A RU 93004678 A RU93004678 A RU 93004678A
- Authority
- RU
- Russia
- Prior art keywords
- carbapenem
- production
- methods
- application
- hydrogen
- Prior art date
Links
- 230000000845 anti-microbial Effects 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 title 1
- YZBQHRLRFGPBSL-RXMQYKEDSA-N carbapenem Chemical class C1C=CN2C(=O)C[C@H]21 YZBQHRLRFGPBSL-RXMQYKEDSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 229940064005 Antibiotic throat preparations Drugs 0.000 claims 1
- 229940083879 Antibiotics FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE Drugs 0.000 claims 1
- 229940042052 Antibiotics for systemic use Drugs 0.000 claims 1
- 229940042786 Antitubercular Antibiotics Drugs 0.000 claims 1
- 229940093922 Gynecological Antibiotics Drugs 0.000 claims 1
- 229940024982 Topical Antifungal Antibiotics Drugs 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000003115 biocidal Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000009910 diseases by infectious agent Diseases 0.000 claims 1
- 125000004185 ester group Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 229940079866 intestinal antibiotics Drugs 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 230000000813 microbial Effects 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 229940005935 ophthalmologic Antibiotics Drugs 0.000 claims 1
Claims (1)
- Предложены соединения формулы
в которой R1 - водород или метил, R2 - водород, необязательно замещенный алифатический углеводородный радикал или ацилимидоил, R3 представляет собой водород или эфирную группу, а Q представляет собой необязательно кватернизованную азотсодержащую группу, пригодные для использования в качестве антибиотиков, которые резистентны к действию дегидропептидазы и, следовательно, пригодны для лечения многих микробных инфекций.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5216392 | 1992-03-11 | ||
| JP4-52163 | 1992-03-11 | ||
| JP24495392 | 1992-09-14 | ||
| JP4-244953 | 1992-09-14 | ||
| JP4-246578 | 1992-09-16 | ||
| JP24657892 | 1992-09-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93004678A true RU93004678A (ru) | 1996-02-27 |
| RU2097383C1 RU2097383C1 (ru) | 1997-11-27 |
Family
ID=27294566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU9393004678A RU2097383C1 (ru) | 1992-03-11 | 1993-03-11 | Производные карбапенема и способ их получения |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0560613B1 (ru) |
| KR (1) | KR100258225B1 (ru) |
| CN (1) | CN1037180C (ru) |
| AT (1) | ATE173733T1 (ru) |
| AU (1) | AU664422B2 (ru) |
| CA (1) | CA2091486A1 (ru) |
| CZ (1) | CZ290002B6 (ru) |
| DE (1) | DE69322188T2 (ru) |
| DK (1) | DK0560613T3 (ru) |
| ES (1) | ES2125945T3 (ru) |
| FI (1) | FI103046B (ru) |
| HK (1) | HK1011976A1 (ru) |
| HU (1) | HU218676B (ru) |
| IL (1) | IL105020A (ru) |
| MX (1) | MX9301361A (ru) |
| NO (1) | NO303730B1 (ru) |
| NZ (1) | NZ247129A (ru) |
| RU (1) | RU2097383C1 (ru) |
| TW (1) | TW249803B (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101226B (fi) * | 1991-06-04 | 1998-05-15 | Sankyo Co | Menetelmä lääkeaineena käyttökelpoisten 2-£2-(karbonyyli)pyrrolidin-4- yylitio|-6-(1-hydroksietyyli)-1-metyylikarbapen-2-eemi-3-karboksyyliha ppojohdannaisten valmistamiseksi |
| GB9515975D0 (en) | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
| HUP9901376A3 (en) * | 1995-12-21 | 2000-03-28 | Sankyo Company Ltd Chuo Ku | 1-methylcarbapenem derivatives, their use, production thereof and medicaments containing the same |
| CZ342098A3 (cs) * | 1996-04-26 | 1999-02-17 | Sankyo Company, Limited | 1-Methylkarbapenemové deriváty |
| EP0923545A1 (en) | 1996-08-17 | 1999-06-23 | Zeneca Limited | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors |
| AU1415500A (en) * | 1998-12-07 | 2000-06-26 | Sankyo Company Limited | 1-methylcarbapenem derivatives |
| US7041660B2 (en) | 1999-07-06 | 2006-05-09 | Sankyo Company, Limited | Crystalline 1-methylcarbapenem derivatives |
| GB9930318D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| GB9930317D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| JP4480396B2 (ja) * | 2001-09-26 | 2010-06-16 | メルク・シャープ・エンド・ドーム・コーポレイション | カルバペネム化合物の製造方法 |
| JP4792974B2 (ja) * | 2003-12-25 | 2011-10-12 | 小野薬品工業株式会社 | アゼチジン環化合物およびその医薬 |
| CN101367814B (zh) * | 2007-06-28 | 2010-12-15 | 山东轩竹医药科技有限公司 | 被巯基吡咯烷甲酰哌啶取代的培南衍生物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| DE3780344T2 (de) * | 1986-03-27 | 1993-01-28 | Sumitomo Pharma | Beta-lactam-verbindungen und deren herstellung. |
| CA2036163C (en) * | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Novel beta-lactam compounds and their production |
| FI96863C (fi) * | 1990-02-23 | 1996-09-10 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi |
| GB9107363D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| FI101226B (fi) * | 1991-06-04 | 1998-05-15 | Sankyo Co | Menetelmä lääkeaineena käyttökelpoisten 2-£2-(karbonyyli)pyrrolidin-4- yylitio|-6-(1-hydroksietyyli)-1-metyylikarbapen-2-eemi-3-karboksyyliha ppojohdannaisten valmistamiseksi |
| CA2117899A1 (en) * | 1992-04-13 | 1993-10-28 | Masayoshi Murata | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents |
-
1993
- 1993-03-10 FI FI931079A patent/FI103046B/fi active IP Right Grant
- 1993-03-10 HU HU9300677A patent/HU218676B/hu not_active IP Right Cessation
- 1993-03-10 CZ CZ1993393A patent/CZ290002B6/cs not_active IP Right Cessation
- 1993-03-11 AU AU35151/93A patent/AU664422B2/en not_active Ceased
- 1993-03-11 TW TW082101810A patent/TW249803B/zh active
- 1993-03-11 DE DE69322188T patent/DE69322188T2/de not_active Expired - Fee Related
- 1993-03-11 AT AT93301872T patent/ATE173733T1/de not_active IP Right Cessation
- 1993-03-11 KR KR1019930003664A patent/KR100258225B1/ko not_active IP Right Cessation
- 1993-03-11 NZ NZ247129A patent/NZ247129A/en unknown
- 1993-03-11 EP EP93301872A patent/EP0560613B1/en not_active Expired - Lifetime
- 1993-03-11 IL IL105020A patent/IL105020A/xx not_active IP Right Cessation
- 1993-03-11 CN CN93104412A patent/CN1037180C/zh not_active Expired - Fee Related
- 1993-03-11 RU RU9393004678A patent/RU2097383C1/ru not_active IP Right Cessation
- 1993-03-11 MX MX9301361A patent/MX9301361A/es not_active IP Right Cessation
- 1993-03-11 ES ES93301872T patent/ES2125945T3/es not_active Expired - Lifetime
- 1993-03-11 DK DK93301872T patent/DK0560613T3/da active
- 1993-03-11 NO NO930884A patent/NO303730B1/no not_active IP Right Cessation
- 1993-03-11 CA CA002091486A patent/CA2091486A1/en not_active Abandoned
-
1998
- 1998-12-10 HK HK98113079A patent/HK1011976A1/xx not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU93048636A (ru) | 7-/замещенные/-8-/замещенные/-9-/замещенные амино/-6-диметил-6-дезокситетрациклины, промежуточные соединения, способы получения соединений, способ профилактики и лечения и фармацевтическая композиция | |
| RU93055137A (ru) | Гетероцикло-циклические производные аминов, способ получения, промежуточные соединения, фармацевтическая композиция, способ лечения | |
| RU95113967A (ru) | Амино-замещенные пиразолы, композиция, обладающая crf антагонистической активностью, способ лечения, промежуточный продукт | |
| TR199802385T2 (xx) | TNF inhibit�rleri ve FDE-IV inhibit�rleri olarak kinolin karboksamidler. | |
| RU93004678A (ru) | Противомикробные производные карбапенема, способы их получения и применение | |
| ATE104972T1 (de) | Substituierte pyrrole. | |
| FI951468A (fi) | Lipopeptidijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö | |
| HU9403690D0 (en) | Branched-amino-substituted thiazoles, process for their preparation and the pharmaceutical compositions which contan them | |
| ES2125945T3 (es) | Derivados antimicrobianos del carbapenemo, su preparacion y su utilizacion terapeutica. | |
| KR850000451A (ko) | 결정성 나트륨 아목시실린의 제조방법 | |
| DE3861271D1 (de) | Basisch substituierte benzofurancarbonsaeureamide, verfahren zu ihrer herstellung und sie enthaltende therapeutische mittel. | |
| ES8600238A1 (es) | Un procedimiento para preparar derivados de acido 1-aroil-5-oxo-2-pirrolidin-propanoico | |
| ES2049703T3 (es) | Derivados sulfurados de acidos biliares. | |
| FI960588A0 (fi) | Mikrobisideina käytettäviä tiokarbamoyyliyhdisteitä | |
| RU94026904A (ru) | Производные макфортин/парагерквамида, способ их получения, составы, используемые как противопаразитные агенты, способы борьбы с инфекциями, биологически чистая культура | |
| FI911616A0 (fi) | Substituerade 3-tia- eller 3-oxa-alkyl -flavoner, foerfarande foer deras framstaellning, deras anvaendning, pao dessa foereningar baserade laekemedel samt mellanprodukter. | |
| EE9400233A (et) | 1,5,6,7-tetrahüdro-4H-indasool-4-ooni sisaldav ravim, uus 1,5,6,7-tetrahüdro-4H-indasool-4-oon ja meetodid nende saamiseks | |
| IT1265430B1 (it) | Derivati del pirrolo e loro impieghi | |
| PE64099A1 (es) | Antibiotico derivado de cefalosporinas | |
| RU93056616A (ru) | Средство для лечения и профилактики заболеваний организмов, обитающих в водной среде, вызванных грам-положительными бактериями |