RU2746755C2 - Химерный белок - Google Patents

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RU2746755C2
RU2746755C2 RU2017132293A RU2017132293A RU2746755C2 RU 2746755 C2 RU2746755 C2 RU 2746755C2 RU 2017132293 A RU2017132293 A RU 2017132293A RU 2017132293 A RU2017132293 A RU 2017132293A RU 2746755 C2 RU2746755 C2 RU 2746755C2
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gly
cell
leu
caspase
cells
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RU2017132293A
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RU2017132293A (ru
RU2017132293A3 (enExample
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Мартен ПЮЛЕ
Райан ТРАУБРИДЖ
Эдвард ХОДЖКИН
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Отолус Лимитед
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    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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RU2017132293A 2015-02-24 2016-02-23 Химерный белок RU2746755C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1503133.9 2015-02-24
GB201503133A GB201503133D0 (en) 2015-02-24 2015-02-24 Chimeric protein
PCT/GB2016/050451 WO2016135470A1 (en) 2015-02-24 2016-02-23 Chimeric protein

Publications (3)

Publication Number Publication Date
RU2017132293A RU2017132293A (ru) 2019-03-25
RU2017132293A3 RU2017132293A3 (enExample) 2019-06-19
RU2746755C2 true RU2746755C2 (ru) 2021-04-20

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RU2017132293A RU2746755C2 (ru) 2015-02-24 2016-02-23 Химерный белок

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US (3) US10098911B2 (enExample)
EP (2) EP3197453B9 (enExample)
JP (4) JP6836508B2 (enExample)
KR (2) KR102601849B1 (enExample)
CN (2) CN116425882A (enExample)
AU (1) AU2016225190B2 (enExample)
CA (1) CA2973107C (enExample)
CL (1) CL2017002134A1 (enExample)
DK (1) DK3197453T3 (enExample)
ES (1) ES2930623T3 (enExample)
GB (1) GB201503133D0 (enExample)
HU (1) HUE060267T2 (enExample)
IL (1) IL252840B (enExample)
MX (1) MX392658B (enExample)
PL (1) PL3197453T3 (enExample)
PT (1) PT3197453T (enExample)
RU (1) RU2746755C2 (enExample)
SG (1) SG11201705300VA (enExample)
WO (1) WO2016135470A1 (enExample)
ZA (1) ZA201704231B (enExample)

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GB201503133D0 (en) * 2015-02-24 2015-04-08 Ucl Business Plc And Syncona Partners Llp Chimeric protein
CA3007473A1 (en) * 2015-12-14 2017-06-22 Bellicum Pharmaceuticals, Inc. Dual controls for therapeutic cell activation or elimination
WO2018068022A1 (en) * 2016-10-06 2018-04-12 Poseida Therapeutics, Inc. Inducible caspases and methods for use
CA3045667A1 (en) 2016-12-13 2018-06-21 Seattle Children's Hospital (dba Seattle Children's Research Institute) Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo
WO2018129563A1 (en) 2017-01-09 2018-07-12 Oisin Biotechnologies Fusogenic lipid nanoparticles and methods for manufacturing and use for therapeutic protein production and for treatment
GB201709203D0 (en) 2017-06-09 2017-07-26 Autolus Ltd Antigen-binding domain
WO2019025800A1 (en) * 2017-08-02 2019-02-07 Autolus Limited CELLS EXPRESSING A CHIMERIC ANTIGENIC RECEPTOR OR A MANIPULATED TCR AND COMPRISING A SELECTIVELY EXPRESSED SELECTIVE NUCLEOTIDE SEQUENCE
CN109593721B (zh) * 2017-09-30 2022-11-01 亘喜生物科技（上海）有限公司 具有自杀基因开关的靶向人间皮素的工程化免疫细胞
GB201716728D0 (en) 2017-10-12 2017-11-29 Autolus Ltd Cell
GB201717524D0 (en) 2017-10-25 2017-12-06 Autolus Ltd Vectors
EP3703689A1 (en) * 2017-11-01 2020-09-09 Allogene Therapeutics, Inc. Modified caspase-9 polypeptides and methods of use thereof
JP7412006B2 (ja) * 2018-03-14 2024-01-12 メディジーン イミュノテラピーズ ゲーエムベーハー 誘導性ｔ細胞レセプター及びその使用
GB201805918D0 (en) 2018-04-10 2018-05-23 Autolus Ltd Cell
WO2019204666A1 (en) 2018-04-18 2019-10-24 Oisin Biotechnologies, Inc. Fusogenic lipid nanoparticles and methods for the manufacture and use thereof for the target cell-specific production of a therapeutic protein and for the treatment of a disease, condition, or disorder associated with a target cell
CA3091490A1 (en) 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Rapamycin resistant cells
GB201813178D0 (en) 2018-08-13 2018-09-26 Autolus Ltd Cell
EP3934666A1 (en) 2019-03-08 2022-01-12 Autolus Limited Compositions and methods comprising engineered chimeric antigen receptor and modulator of car
GB201903237D0 (en) 2019-03-08 2019-04-24 Autolus Ltd Method
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