JP6836508B2 - キメラタンパク質 - Google Patents

キメラタンパク質 Download PDF

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JP6836508B2
JP6836508B2 JP2017542093A JP2017542093A JP6836508B2 JP 6836508 B2 JP6836508 B2 JP 6836508B2 JP 2017542093 A JP2017542093 A JP 2017542093A JP 2017542093 A JP2017542093 A JP 2017542093A JP 6836508 B2 JP6836508 B2 JP 6836508B2
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cells
domain
caspase
nucleic acid
chimeric protein
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JP2018506975A5 (enExample
JP2018506975A (ja
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マーティン プーレ，
マーティン プーレ，
ライアン トローブリッジ，
ライアン トローブリッジ，
エドワード ホジキン，
エドワード ホジキン，
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UCL Business Ltd
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UCL Business Ltd
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N15/09—Recombinant DNA-technology
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/0602—Vertebrate cells
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    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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JP2017542093A 2015-02-24 2016-02-23 キメラタンパク質 Active JP6836508B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1503133.9 2015-02-24
GB201503133A GB201503133D0 (en) 2015-02-24 2015-02-24 Chimeric protein
PCT/GB2016/050451 WO2016135470A1 (en) 2015-02-24 2016-02-23 Chimeric protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020038667A Division JP2020078359A (ja) 2015-02-24 2020-03-06 キメラタンパク質

Publications (3)

Publication Number Publication Date
JP2018506975A JP2018506975A (ja) 2018-03-15
JP2018506975A5 JP2018506975A5 (enExample) 2019-02-14
JP6836508B2 true JP6836508B2 (ja) 2021-03-03

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017542093A Active JP6836508B2 (ja) 2015-02-24 2016-02-23 キメラタンパク質
JP2020038667A Withdrawn JP2020078359A (ja) 2015-02-24 2020-03-06 キメラタンパク質
JP2022092922A Pending JP2022111273A (ja) 2015-02-24 2022-06-08 キメラタンパク質
JP2024111258A Pending JP2024133176A (ja) 2015-02-24 2024-07-10 キメラタンパク質

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020038667A Withdrawn JP2020078359A (ja) 2015-02-24 2020-03-06 キメラタンパク質
JP2022092922A Pending JP2022111273A (ja) 2015-02-24 2022-06-08 キメラタンパク質
JP2024111258A Pending JP2024133176A (ja) 2015-02-24 2024-07-10 キメラタンパク質

Country Status (20)

Country Link
US (3) US10098911B2 (enExample)
EP (2) EP3197453B9 (enExample)
JP (4) JP6836508B2 (enExample)
KR (2) KR102601849B1 (enExample)
CN (2) CN116425882A (enExample)
AU (1) AU2016225190B2 (enExample)
CA (1) CA2973107C (enExample)
CL (1) CL2017002134A1 (enExample)
DK (1) DK3197453T3 (enExample)
ES (1) ES2930623T3 (enExample)
GB (1) GB201503133D0 (enExample)
HU (1) HUE060267T2 (enExample)
IL (1) IL252840B (enExample)
MX (1) MX392658B (enExample)
PL (1) PL3197453T3 (enExample)
PT (1) PT3197453T (enExample)
RU (1) RU2746755C2 (enExample)
SG (1) SG11201705300VA (enExample)
WO (1) WO2016135470A1 (enExample)
ZA (1) ZA201704231B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201503133D0 (en) * 2015-02-24 2015-04-08 Ucl Business Plc And Syncona Partners Llp Chimeric protein
CA3007473A1 (en) * 2015-12-14 2017-06-22 Bellicum Pharmaceuticals, Inc. Dual controls for therapeutic cell activation or elimination
WO2018068022A1 (en) * 2016-10-06 2018-04-12 Poseida Therapeutics, Inc. Inducible caspases and methods for use
CA3045667A1 (en) 2016-12-13 2018-06-21 Seattle Children's Hospital (dba Seattle Children's Research Institute) Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo
WO2018129563A1 (en) 2017-01-09 2018-07-12 Oisin Biotechnologies Fusogenic lipid nanoparticles and methods for manufacturing and use for therapeutic protein production and for treatment
GB201709203D0 (en) 2017-06-09 2017-07-26 Autolus Ltd Antigen-binding domain
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