RU2743718C2 - Гетероарильные соединения в качестве ингибиторов irak и их применения - Google Patents

Гетероарильные соединения в качестве ингибиторов irak и их применения Download PDF

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RU2743718C2
RU2743718C2 RU2017120274A RU2017120274A RU2743718C2 RU 2743718 C2 RU2743718 C2 RU 2743718C2 RU 2017120274 A RU2017120274 A RU 2017120274A RU 2017120274 A RU2017120274 A RU 2017120274A RU 2743718 C2 RU2743718 C2 RU 2743718C2
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mmol
methyl
pyrazol
column
hplc
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RU2017120274A
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Кэтрин ЖОРАН-ЛЕБРЕН
Рейналдо ДЖОУНС
Анни Чо ВОН
Нган НГУЙЕН
Тереза Л. Джонсон
Лизбет Силест ДЕСЕЛЬМ
Каусик ПАНДА
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Мерк Патент Гмбх
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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RU2017120274A 2014-11-20 2015-11-19 Гетероарильные соединения в качестве ингибиторов irak и их применения RU2743718C2 (ru)

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Application Number Priority Date Filing Date Title
US201462082231P 2014-11-20 2014-11-20
US62/082,231 2014-11-20
PCT/US2015/061463 WO2016081679A1 (en) 2014-11-20 2015-11-19 Heteroaryl compounds as irak inhibitors and uses thereof

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RU2017120274A RU2017120274A (ru) 2018-12-20
RU2017120274A3 RU2017120274A3 (cg-RX-API-DMAC7.html) 2019-03-18
RU2743718C2 true RU2743718C2 (ru) 2021-02-24

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CN113750094A (zh) 2015-04-22 2021-12-07 里格尔药品股份有限公司 吡唑化合物以及制备和使用该化合物的方法
WO2017144633A1 (en) * 2016-02-25 2017-08-31 Asceneuron S. A. Glycosidase inhibitors
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
EP4212523A1 (en) 2016-10-26 2023-07-19 Rigel Pharmaceuticals, Inc. Pyrazole amide compounds as irak inhibitors
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