RU2722075C2 - Картридж для очистки нуклеиновой кислоты - Google Patents

Картридж для очистки нуклеиновой кислоты Download PDF

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RU2722075C2
RU2722075C2 RU2017110274A RU2017110274A RU2722075C2 RU 2722075 C2 RU2722075 C2 RU 2722075C2 RU 2017110274 A RU2017110274 A RU 2017110274A RU 2017110274 A RU2017110274 A RU 2017110274A RU 2722075 C2 RU2722075 C2 RU 2722075C2
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Russia
Prior art keywords
port
filter
chamber
flow path
allowing
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RU2017110274A
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English (en)
Russian (ru)
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RU2017110274A (ru
RU2017110274A3 (enExample
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ПОРРАС Франсеск БЕНИТЕС
ГОМЕС Хосеп ПАРЕХА
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Стат-Диагностика Энд Инновэйшн Сл
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/146—Employing pressure sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/14—Means for pressure control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
RU2017110274A 2014-09-03 2015-09-02 Картридж для очистки нуклеиновой кислоты RU2722075C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14183411.9 2014-09-03
EP14183411.9A EP2992958A1 (en) 2014-09-03 2014-09-03 Nucleic acid purification cartridge
PCT/EP2015/070045 WO2016034620A1 (en) 2014-09-03 2015-09-02 Nucleic acid purification cartridge

Publications (3)

Publication Number Publication Date
RU2017110274A RU2017110274A (ru) 2018-10-03
RU2017110274A3 RU2017110274A3 (enExample) 2019-02-22
RU2722075C2 true RU2722075C2 (ru) 2020-05-26

Family

ID=51518547

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017110274A RU2722075C2 (ru) 2014-09-03 2015-09-02 Картридж для очистки нуклеиновой кислоты

Country Status (12)

Country Link
US (1) US10793849B2 (enExample)
EP (2) EP2992958A1 (enExample)
JP (1) JP6800144B2 (enExample)
KR (1) KR102458490B1 (enExample)
CN (1) CN106999928B (enExample)
AU (1) AU2015310942B2 (enExample)
BR (1) BR112017004191B1 (enExample)
CA (1) CA2959954C (enExample)
ES (1) ES2873362T3 (enExample)
RU (1) RU2722075C2 (enExample)
WO (1) WO2016034620A1 (enExample)
ZA (1) ZA201702211B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
EP4279610A3 (en) 2013-03-15 2024-01-03 ModernaTX, Inc. Ribonucleic acid purification
US10077439B2 (en) 2013-03-15 2018-09-18 Modernatx, Inc. Removal of DNA fragments in mRNA production process
EP2971033B8 (en) 2013-03-15 2019-07-10 ModernaTX, Inc. Manufacturing methods for production of rna transcripts
WO2014144767A1 (en) 2013-03-15 2014-09-18 Moderna Therapeutics, Inc. Ion exchange purification of mrna
EP3052511A4 (en) 2013-10-02 2017-05-31 Moderna Therapeutics, Inc. Polynucleotide molecules and uses thereof
US10286086B2 (en) 2014-06-19 2019-05-14 Modernatx, Inc. Alternative nucleic acid molecules and uses thereof
AU2015289656A1 (en) 2014-07-16 2017-02-16 Modernatx, Inc. Circular polynucleotides
EP4101930A1 (en) 2015-09-17 2022-12-14 ModernaTX, Inc. Polynucleotides containing a stabilizing tail region
WO2017049286A1 (en) 2015-09-17 2017-03-23 Moderna Therapeutics, Inc. Polynucleotides containing a morpholino linker
US12385034B2 (en) 2016-06-24 2025-08-12 Modernatx, Inc. Methods and apparatus for filtration
GB201703383D0 (en) 2017-03-02 2017-04-19 Gargle Tech Ltd Testing for particulates
KR102065649B1 (ko) * 2017-12-28 2020-01-13 에스디 바이오센서 주식회사 핵산 추출용 카트리지의 피스톤
US11680877B2 (en) 2018-09-05 2023-06-20 Hero Scientific Ltd. Testing for particulates
GB201819417D0 (en) * 2018-11-29 2019-01-16 Quantumdx Group Ltd Vacuum-assisted drying of filters in microfluidic systems
WO2020257102A1 (en) * 2019-06-19 2020-12-24 Merck Sharp & Dohme Corp. Containment system for mixing dry powders with solvents during drug production or processing
BR112022003781A2 (pt) * 2019-08-30 2022-05-24 Boehringer Ingelheim Vetmedica Gmbh Instrumento de filtro, kit e método para pré-tratar uma amostra
WO2021181339A1 (en) 2020-03-11 2021-09-16 Hero Scientific Ltd. Testing devices
CN111545256B (zh) * 2020-03-31 2022-05-13 深圳市刚竹医疗科技有限公司 离心微流控芯片
EP4165385B1 (en) 2021-01-06 2024-04-17 Hero Scientific Ltd Filtration sampling devices
CN112899132B (zh) * 2021-01-13 2021-10-15 上海金鑫生物科技有限公司 一种用于核酸提取与纯化的硅胶过滤吸头
CN119875797B (zh) * 2025-03-28 2025-07-08 湖南远泰生物技术有限公司 质粒dna滤纸洗脱组件、自动微流控系统及洗脱方法

Citations (6)

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Publication number Priority date Publication date Assignee Title
EP1300680A2 (en) * 1994-11-08 2003-04-09 Phoenix Medical Limited Body fluid testing
US20120107799A1 (en) * 2010-10-29 2012-05-03 Longhorn Vaccines & Diagnostics LLC. Disposable, rapid extraction apparatus and methods
US20120178179A1 (en) * 2011-01-10 2012-07-12 Ji Tae Kim Diagnostic cartridge and control method for diagnostic cartridge
US20130086998A1 (en) * 2011-10-05 2013-04-11 Samsung Electronics Co., Ltd. Fluid controlling apparatus and method of controlling fluid by using the same
US20130288234A1 (en) * 2012-04-18 2013-10-31 Pathogenetix, Inc. Device for preparing a sample
US8747669B1 (en) * 2005-12-29 2014-06-10 Spf Innovations, Llc Method and apparatus for the filtration of biological samples

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US4617102A (en) 1985-03-21 1986-10-14 Lifecodes Corp. Process and apparatus for purifying and concentrating DNA from crude mixtures containing DNA
FR2657543B1 (fr) * 1990-01-26 1992-12-18 Biocom Sa Dispositif modulaire pour le recueil, l'incubation, la filtration d'echantillons multiples.
US5380437A (en) * 1993-02-02 1995-01-10 Biomedical Research And Development Laboratories, Inc. Multifunctional filtration apparatus
JP2001501527A (ja) * 1996-09-18 2001-02-06 プロメガ コーポレイション 改良されたろ過システム及び方法
JP2002345465A (ja) * 2001-05-24 2002-12-03 Fuji Photo Film Co Ltd 核酸精製ユニット及び核酸精製方法
EP2234916A4 (en) * 2008-01-22 2016-08-10 Integenx Inc UNIVERSAL SPECIMEN PREPARATION SYSTEM AND ITS USE IN AN INTEGRATED ANALYSIS SYSTEM
JP5782384B2 (ja) * 2009-02-03 2015-09-24 ネットバイオ・インコーポレーテッドＮｅｔＢｉｏ， Ｉｎｃ． 未処理試料から核酸を単離するための自己完結型装置および精製方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1300680A2 (en) * 1994-11-08 2003-04-09 Phoenix Medical Limited Body fluid testing
US8747669B1 (en) * 2005-12-29 2014-06-10 Spf Innovations, Llc Method and apparatus for the filtration of biological samples
US20120107799A1 (en) * 2010-10-29 2012-05-03 Longhorn Vaccines & Diagnostics LLC. Disposable, rapid extraction apparatus and methods
US20120178179A1 (en) * 2011-01-10 2012-07-12 Ji Tae Kim Diagnostic cartridge and control method for diagnostic cartridge
US20130086998A1 (en) * 2011-10-05 2013-04-11 Samsung Electronics Co., Ltd. Fluid controlling apparatus and method of controlling fluid by using the same
US20130288234A1 (en) * 2012-04-18 2013-10-31 Pathogenetix, Inc. Device for preparing a sample

Also Published As

Publication number Publication date
EP2992958A1 (en) 2016-03-09
JP2017532016A (ja) 2017-11-02
CA2959954C (en) 2022-07-19
EP3188838A1 (en) 2017-07-12
CN106999928B (zh) 2021-05-18
AU2015310942B2 (en) 2021-02-04
RU2017110274A (ru) 2018-10-03
ZA201702211B (en) 2018-08-29
KR20170045339A (ko) 2017-04-26
BR112017004191A2 (pt) 2017-12-12
US20170283792A1 (en) 2017-10-05
BR112017004191B1 (pt) 2022-07-05
KR102458490B1 (ko) 2022-10-26
EP3188838B1 (en) 2021-04-14
ES2873362T3 (es) 2021-11-03
US10793849B2 (en) 2020-10-06
WO2016034620A1 (en) 2016-03-10
AU2015310942A1 (en) 2017-04-20
JP6800144B2 (ja) 2020-12-16
RU2017110274A3 (enExample) 2019-02-22
CA2959954A1 (en) 2016-03-10
CN106999928A (zh) 2017-08-01

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