RU2706787C2 - Модель сухого кератоконъюнктивита на животных и способы применения таких животных - Google Patents
Модель сухого кератоконъюнктивита на животных и способы применения таких животных Download PDFInfo
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- RU2706787C2 RU2706787C2 RU2017118978A RU2017118978A RU2706787C2 RU 2706787 C2 RU2706787 C2 RU 2706787C2 RU 2017118978 A RU2017118978 A RU 2017118978A RU 2017118978 A RU2017118978 A RU 2017118978A RU 2706787 C2 RU2706787 C2 RU 2706787C2
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A—HUMAN NECESSITIES
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- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
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| US201462086263P | 2014-12-02 | 2014-12-02 | |
| US62/086,263 | 2014-12-02 | ||
| PCT/US2015/063084 WO2016089807A1 (en) | 2014-12-02 | 2015-12-01 | Animal model for dry eye and methods of use of such animals |
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| RU2017118978A RU2017118978A (ru) | 2019-01-09 |
| RU2017118978A3 RU2017118978A3 (enExample) | 2019-06-04 |
| RU2706787C2 true RU2706787C2 (ru) | 2019-11-21 |
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| KR20190068575A (ko) * | 2016-10-14 | 2019-06-18 | 이콤 메디칼 게엠베하 | 안구 표면 항상성의 확립, 회복 및 보존 방법 |
| WO2019202017A1 (en) | 2018-04-18 | 2019-10-24 | i.com medical GmbH | High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease |
| US12268706B2 (en) | 2019-01-31 | 2025-04-08 | i.com medical GmbH | Hyaluronic acid for relief of idiopathic ocular pain |
| KR102429281B1 (ko) * | 2020-05-25 | 2022-08-05 | (주)노바셀테크놀로지 | 신규 안구건조증 치료용 약학적 조성물 |
| CN113519461A (zh) * | 2021-07-06 | 2021-10-22 | 江西中洪博元生物技术有限公司 | 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用 |
| WO2023215261A1 (en) * | 2022-05-02 | 2023-11-09 | Ocular Services On Demand, Llc | Mammalian eye models |
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| WO2012013884A1 (fr) * | 2010-07-29 | 2012-02-02 | Laboratoires Fournier Sa | Composes pour le traitement/la prevention des maladies inflammatoires oculaires |
Non-Patent Citations (3)
| Title |
|---|
| BEYAZYILDIZ Е. et al. Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome * |
| LI R. et al. An NGF Mimetic, MIM-D3, Demonstrates Therapeutic Efficacy in a Rat Model of Scopoloamine-Induced Dry Eye//ARVO Annual Meeting Abstract, April 2009, Volume 50, Issue 13, 3661, . * |
| LI R. et al. An NGF Mimetic, MIM-D3, Demonstrates Therapeutic Efficacy in a Rat Model of Scopoloamine-Induced Dry Eye//ARVO Annual Meeting Abstract, April 2009, Volume 50, Issue 13, 3661, реферат. BEYAZYILDIZ Е. et al. Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome Model//Stem Cells Int. 2014; 2014: 250230.Published online 2014 Jul 17. doi: 10.1155/2014/250230. * |
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| Publication number | Publication date |
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| ES2759729T3 (es) | 2020-05-12 |
| JP6692808B2 (ja) | 2020-05-13 |
| EP3226853A1 (en) | 2017-10-11 |
| RU2017118978A (ru) | 2019-01-09 |
| CN107106553A (zh) | 2017-08-29 |
| MX2017007295A (es) | 2018-03-12 |
| ZA201703052B (en) | 2019-03-27 |
| IL252077A0 (en) | 2017-07-31 |
| CA2967432A1 (en) | 2016-06-09 |
| RU2017118978A3 (enExample) | 2019-06-04 |
| SG11201703572SA (en) | 2017-05-30 |
| WO2016089807A1 (en) | 2016-06-09 |
| US20170360013A1 (en) | 2017-12-21 |
| EP3226853B1 (en) | 2019-09-04 |
| JP2018500546A (ja) | 2018-01-11 |
| KR20170100483A (ko) | 2017-09-04 |
| AU2015355169A1 (en) | 2017-05-25 |
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