MX2017007295A - Modelo animal de ojo seco y metodos de uso de dichos animales. - Google Patents

Modelo animal de ojo seco y metodos de uso de dichos animales.

Info

Publication number
MX2017007295A
MX2017007295A MX2017007295A MX2017007295A MX2017007295A MX 2017007295 A MX2017007295 A MX 2017007295A MX 2017007295 A MX2017007295 A MX 2017007295A MX 2017007295 A MX2017007295 A MX 2017007295A MX 2017007295 A MX2017007295 A MX 2017007295A
Authority
MX
Mexico
Prior art keywords
methods
dry eye
animal model
animals
treatments
Prior art date
Application number
MX2017007295A
Other languages
English (en)
Spanish (es)
Inventor
Cao Jingtai
Hu Ying
Yuan Ming
Romano Carmelo
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2017007295A publication Critical patent/MX2017007295A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/20Animals treated with compounds which are neither proteins nor nucleic acids
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Animal Husbandry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Urology & Nephrology (AREA)
  • Mathematical Analysis (AREA)
  • Mathematical Optimization (AREA)
  • Educational Technology (AREA)
  • Educational Administration (AREA)
  • Business, Economics & Management (AREA)
  • Pure & Applied Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
MX2017007295A 2014-12-02 2015-12-01 Modelo animal de ojo seco y metodos de uso de dichos animales. MX2017007295A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462086263P 2014-12-02 2014-12-02
PCT/US2015/063084 WO2016089807A1 (en) 2014-12-02 2015-12-01 Animal model for dry eye and methods of use of such animals

Publications (1)

Publication Number Publication Date
MX2017007295A true MX2017007295A (es) 2018-03-12

Family

ID=55024246

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017007295A MX2017007295A (es) 2014-12-02 2015-12-01 Modelo animal de ojo seco y metodos de uso de dichos animales.

Country Status (14)

Country Link
US (1) US20170360013A1 (enExample)
EP (1) EP3226853B1 (enExample)
JP (1) JP6692808B2 (enExample)
KR (1) KR20170100483A (enExample)
CN (1) CN107106553A (enExample)
AU (1) AU2015355169A1 (enExample)
CA (1) CA2967432A1 (enExample)
ES (1) ES2759729T3 (enExample)
IL (1) IL252077A0 (enExample)
MX (1) MX2017007295A (enExample)
RU (1) RU2706787C2 (enExample)
SG (1) SG11201703572SA (enExample)
WO (1) WO2016089807A1 (enExample)
ZA (1) ZA201703052B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190068575A (ko) * 2016-10-14 2019-06-18 이콤 메디칼 게엠베하 안구 표면 항상성의 확립, 회복 및 보존 방법
WO2019202017A1 (en) 2018-04-18 2019-10-24 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
KR102429281B1 (ko) * 2020-05-25 2022-08-05 (주)노바셀테크놀로지 신규 안구건조증 치료용 약학적 조성물
CN113519461A (zh) * 2021-07-06 2021-10-22 江西中洪博元生物技术有限公司 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用
WO2023215261A1 (en) * 2022-05-02 2023-11-09 Ocular Services On Demand, Llc Mammalian eye models

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003532629A (ja) * 1999-09-08 2003-11-05 ワトソン ファーマシューティカルズ, インコーポレイテッド 第4アンモニウム塩の経皮薬剤放出への使用
JP5878172B2 (ja) * 2010-07-29 2016-03-08 ラボラトワール フルニエ エスアーエス 炎症性眼疾患の治療/予防用化合物

Also Published As

Publication number Publication date
ES2759729T3 (es) 2020-05-12
JP6692808B2 (ja) 2020-05-13
EP3226853A1 (en) 2017-10-11
RU2017118978A (ru) 2019-01-09
CN107106553A (zh) 2017-08-29
ZA201703052B (en) 2019-03-27
IL252077A0 (en) 2017-07-31
CA2967432A1 (en) 2016-06-09
RU2017118978A3 (enExample) 2019-06-04
SG11201703572SA (en) 2017-05-30
WO2016089807A1 (en) 2016-06-09
US20170360013A1 (en) 2017-12-21
EP3226853B1 (en) 2019-09-04
JP2018500546A (ja) 2018-01-11
KR20170100483A (ko) 2017-09-04
RU2706787C2 (ru) 2019-11-21
AU2015355169A1 (en) 2017-05-25

Similar Documents

Publication Publication Date Title
IL272339A (en) Cellular models of and therapies for ocular diseases
EP3534772A4 (en) ORBITAL FABRIC SPREADER
IL252159A0 (en) Methods and formulations for the treatment of diseases of the blood vessels of the eye
DK3142637T3 (da) Keratin treatment formulations and methods
IL249061B (en) Combination, composition, and method of administering the combination or composition to animals
MX2017007295A (es) Modelo animal de ojo seco y metodos de uso de dichos animales.
DK3151875T3 (da) Humane lever-scaffolds
EP3518783A4 (en) DEVICE AND METHOD FOR TISSUE REDUCTION
IL259721A (en) Methods for determining the sex of poultry embryos in their egg and means for this
EP3585393A4 (en) FORMULAS FOR EYE TREATMENTS
MX2017005975A (es) Anticuerpos anti factor de crecimiento derivado de plaquetas b (pdgf-b) y metodos de uso.
MX2017000374A (es) Metodos y composiciones que regulan el crecimiento del pelo.
MX392383B (es) Metodos para tratar afecciones oculares.
TWD169884S (zh) 動物互動裝置
HUE063641T2 (hu) Készítmények és eljárások immunválaszok modulálására és/vagy stimulálására emberben és/vagy állatban
GB201705386D0 (en) Device for use in the humane slaughter of animals
GB201705390D0 (en) Device for use in the humane slaughter of animals
HUE048864T2 (hu) Lizobaktin szarvasmarhafélék tõgygyulladásának kezelésében történõ alkalmazásra
HK1239525A1 (en) Animal model for dry eye and methods of use of such animals
DK3177229T3 (da) Kunstig insemineringssonde til kvæg såsom svin
PL3302463T3 (pl) Zastosowanie 3 deoksyantocyjanidyn w leczeniu chorób oczu
GB201506044D0 (en) Methods for determining the effect of an agent on tissue stem cells
ZA201906465B (en) Compositions and methods for treating dry eye diseases
TH1601002237A (th) องค์ประกอบเสริมฤทธิ์ฆ่าศัตรูพืชเเละสัตว์เเละวิธีที่เกี่ยวข้อง
ES1211138Y (es) Dispositivo para entrenamiento endoscópico con modelo animal ex vivo