KR20170100483A - 건성안을 위한 동물 모델 및 이러한 동물의 이용 방법 - Google Patents
건성안을 위한 동물 모델 및 이러한 동물의 이용 방법 Download PDFInfo
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- KR20170100483A KR20170100483A KR1020177012469A KR20177012469A KR20170100483A KR 20170100483 A KR20170100483 A KR 20170100483A KR 1020177012469 A KR1020177012469 A KR 1020177012469A KR 20177012469 A KR20177012469 A KR 20177012469A KR 20170100483 A KR20170100483 A KR 20170100483A
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- scopolamine
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- benzalkonium chloride
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- A—HUMAN NECESSITIES
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- A61K31/13—Amines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
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- A—HUMAN NECESSITIES
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
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- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
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- A—HUMAN NECESSITIES
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- A01K2207/00—Modified animals
- A01K2207/20—Animals treated with compounds which are neither proteins nor nucleic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
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| PCT/US2015/063084 WO2016089807A1 (en) | 2014-12-02 | 2015-12-01 | Animal model for dry eye and methods of use of such animals |
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| ES2909998T3 (es) * | 2016-10-14 | 2022-05-11 | I Com Medical Gmbh | Método para establecer, restablecer y preservar la homeostasis de la superficie ocular |
| US12303527B2 (en) | 2018-04-18 | 2025-05-20 | i.com medical GmbH | High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease |
| US12268706B2 (en) | 2019-01-31 | 2025-04-08 | i.com medical GmbH | Hyaluronic acid for relief of idiopathic ocular pain |
| KR102429281B1 (ko) * | 2020-05-25 | 2022-08-05 | (주)노바셀테크놀로지 | 신규 안구건조증 치료용 약학적 조성물 |
| CN113519461A (zh) * | 2021-07-06 | 2021-10-22 | 江西中洪博元生物技术有限公司 | 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用 |
| WO2023215261A1 (en) * | 2022-05-02 | 2023-11-09 | Ocular Services On Demand, Llc | Mammalian eye models |
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| EP2598131A1 (fr) * | 2010-07-29 | 2013-06-05 | Laboratoires Fournier S.A. | Composes pour le traitement/la prevention des maladies inflammatoires oculaires |
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| ES2759729T3 (es) | 2020-05-12 |
| RU2706787C2 (ru) | 2019-11-21 |
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| AU2015355169A1 (en) | 2017-05-25 |
| WO2016089807A1 (en) | 2016-06-09 |
| ZA201703052B (en) | 2019-03-27 |
| JP2018500546A (ja) | 2018-01-11 |
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