RU2680402C2 - Лечение нарушений свертываемости крови путем введения рекомбинантного фв - Google Patents

Лечение нарушений свертываемости крови путем введения рекомбинантного фв Download PDF

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RU2680402C2
RU2680402C2 RU2017102679A RU2017102679A RU2680402C2 RU 2680402 C2 RU2680402 C2 RU 2680402C2 RU 2017102679 A RU2017102679 A RU 2017102679A RU 2017102679 A RU2017102679 A RU 2017102679A RU 2680402 C2 RU2680402 C2 RU 2680402C2
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rfv
fviii
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RU2017102679A3 (cg-RX-API-DMAC7.html
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Фридрих ШАЙФЛИНГЕР
Петер Турецек
Брюс ЭВЕНШТАЙН
Винг Йен ВОНГ
Тобиас М. СУИТЕР
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Бакстер Интернэшнл Инк.
Бакстер Хелткэр Са
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
RU2017102679A 2011-06-10 2012-06-11 Лечение нарушений свертываемости крови путем введения рекомбинантного фв RU2680402C2 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161495884P 2011-06-10 2011-06-10
US61/495,884 2011-06-10
US201161511901P 2011-07-26 2011-07-26
US61/511,901 2011-07-26
US201161523790P 2011-08-15 2011-08-15
US61/523,790 2011-08-15

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RU2019103386A Division RU2787855C2 (ru) 2011-06-10 2019-02-07 Лечение нарушений свертываемости крови путем введения рекомбинантного фактора виллебранда

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RU2014100107A RU2628537C2 (ru) 2011-06-10 2012-06-11 Лечение нарушений свертываемости крови путем введения рекомбинантного фв

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DK2796145T3 (da) 2013-04-22 2018-01-29 Csl Ltd Et kovalent kompleks af von Willebrand-faktor og faktor VIII linket af en disulfidbro
NL2013007B1 (en) 2014-06-16 2016-07-05 Ablynx Nv Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
FR3034669B1 (fr) * 2015-04-07 2020-02-14 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Nouvelle utilisation du facteur von willebrand
PL3442656T3 (pl) 2016-04-15 2024-04-29 Takeda Pharmaceutical Company Limited Sposób i aparat do zapewniania farmakokinetycznego schematu dawkowania leku
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JP7307047B2 (ja) * 2017-07-07 2023-07-11 武田薬品工業株式会社 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療
US20190091298A1 (en) * 2017-07-07 2019-03-28 Baxalta Incorporated Treatment of patients with severe von willebrand disease undergoing elective surgery by administration of recombinant vwf
CA3089211A1 (en) 2018-02-06 2019-08-15 Ablynx Nv Methods of treating initial episode of ttp with immunoglobulin single variable domains
UA129762C2 (uk) * 2018-03-21 2025-07-30 Такеда Фармасьютікал Компані Лімітед Розділення vwf і пропептиду vwf хроматографічним методом
SG11202108325YA (en) * 2019-02-01 2021-08-30 Takeda Pharmaceuticals Co Methods of prophylactic treatment using recombinant vwf (rvwf)
CN114929260A (zh) * 2019-09-11 2022-08-19 武田药品工业株式会社 与冯维勒布兰德因子和补体c1q的复合物相关的治疗方法
WO2021158777A1 (en) 2020-02-04 2021-08-12 Baxalta Incorporated Treatment of menorrhagia in patients with severe von willebrand disease by administration of recombinant vwf
AU2021387981A1 (en) * 2020-11-24 2023-07-06 Band Therapeutics, Llc Compositions and methods for treatment of bleeding disorders
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KR20190041032A (ko) 2019-04-19
RU2014100107A (ru) 2015-07-20
PT2717905T (pt) 2018-07-02
KR20200091476A (ko) 2020-07-30
AU2020200026A1 (en) 2020-01-30
US20160184403A1 (en) 2016-06-30
HRP20180962T1 (hr) 2018-10-19
LT2717905T (lt) 2018-10-10
MX2020000083A (es) 2020-08-06
EP2717905B1 (en) 2018-05-23
PT3412305T (pt) 2021-01-29
RU2628537C2 (ru) 2017-08-18
CA2838845A1 (en) 2012-12-13
AU2016202299A1 (en) 2016-05-05
AR086904A1 (es) 2014-01-29
ES2860450T3 (es) 2021-10-05
RU2017102679A (ru) 2018-12-19
EP2717905A1 (en) 2014-04-16
RU2017102679A3 (cg-RX-API-DMAC7.html) 2018-12-19
CN107412743A (zh) 2017-12-01
SG10202002591QA (en) 2020-05-28
JP2017019788A (ja) 2017-01-26
DK3412305T3 (da) 2021-03-01
KR101969515B1 (ko) 2019-04-16
PL3858375T3 (pl) 2024-05-20
JP6347468B2 (ja) 2018-06-27
CN103732244A (zh) 2014-04-16
AU2016202299B2 (en) 2017-07-20
TR201808823T4 (tr) 2018-07-23
JP2019048892A (ja) 2019-03-28
EP3858375A1 (en) 2021-08-04
PL3412305T3 (pl) 2021-05-31
SI2717905T1 (sl) 2018-09-28
ES2976169T3 (es) 2024-07-24
KR20140039285A (ko) 2014-04-01
AU2012267458A1 (en) 2014-01-09
EP3412305A1 (en) 2018-12-12
HK1257436A1 (zh) 2019-10-18
AU2022201518B2 (en) 2025-07-03
WO2012171031A1 (en) 2012-12-13
AU2017206235B2 (en) 2019-10-17
US9272021B2 (en) 2016-03-01
AU2022201518A1 (en) 2022-03-24
MX2013014543A (es) 2014-06-11
ES2682249T3 (es) 2018-09-19
HUE039317T2 (hu) 2018-12-28
RU2019103386A3 (cg-RX-API-DMAC7.html) 2022-01-24
KR102319868B1 (ko) 2021-11-01
BR112013031795A2 (pt) 2016-12-20
EP3412305B1 (en) 2021-01-06
SG10201604684WA (en) 2016-07-28
NZ618790A (en) 2015-07-31
US20120316116A1 (en) 2012-12-13
CN107412743B (zh) 2021-07-02
FI3858375T3 (fi) 2024-04-17
AU2017206235A1 (en) 2017-08-03
DK2717905T3 (en) 2018-07-02
PT3858375T (pt) 2024-04-18
JP6527114B2 (ja) 2019-06-05
JP2014516088A (ja) 2014-07-07
DK3858375T3 (da) 2024-04-15
PL2717905T3 (pl) 2018-10-31
CN108210889A (zh) 2018-06-29
CA2838845C (en) 2019-08-06
RU2019103386A (ru) 2020-08-07
EP3858375B1 (en) 2024-03-20
MX350582B (es) 2017-09-11

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