RU2670749C9 - Системы доставки лекарственного средства и способы лечения дисфункции опорожнения мочевого пузыря и других расстройств нижних мочевыводящих путей с использованием троспия - Google Patents

Системы доставки лекарственного средства и способы лечения дисфункции опорожнения мочевого пузыря и других расстройств нижних мочевыводящих путей с использованием троспия Download PDF

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Publication number
RU2670749C9
RU2670749C9 RU2015112196A RU2015112196A RU2670749C9 RU 2670749 C9 RU2670749 C9 RU 2670749C9 RU 2015112196 A RU2015112196 A RU 2015112196A RU 2015112196 A RU2015112196 A RU 2015112196A RU 2670749 C9 RU2670749 C9 RU 2670749C9
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trospium
bladder
day
drug
treatment period
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RU2015112196A
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English (en)
Russian (ru)
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RU2015112196A (ru
RU2670749C2 (ru
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Деннис ГИЗИНГ
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ТАРИС Биомедикал ЛЛК
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
RU2015112196A 2012-09-18 2013-09-18 Системы доставки лекарственного средства и способы лечения дисфункции опорожнения мочевого пузыря и других расстройств нижних мочевыводящих путей с использованием троспия RU2670749C9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702576P 2012-09-18 2012-09-18
US61/702,576 2012-09-18
PCT/US2013/060479 WO2014047221A1 (en) 2012-09-18 2013-09-18 Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium

Publications (3)

Publication Number Publication Date
RU2015112196A RU2015112196A (ru) 2016-11-10
RU2670749C2 RU2670749C2 (ru) 2018-10-25
RU2670749C9 true RU2670749C9 (ru) 2018-12-13

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RU2015112196A RU2670749C9 (ru) 2012-09-18 2013-09-18 Системы доставки лекарственного средства и способы лечения дисфункции опорожнения мочевого пузыря и других расстройств нижних мочевыводящих путей с использованием троспия

Country Status (13)

Country Link
US (2) US10500200B2 (enExample)
EP (1) EP2897616A1 (enExample)
JP (2) JP6600256B2 (enExample)
KR (1) KR102141433B1 (enExample)
CN (2) CN104684556A (enExample)
AU (1) AU2013318146B2 (enExample)
BR (1) BR112015005351A2 (enExample)
CA (1) CA2883855C (enExample)
IL (1) IL237498B (enExample)
MX (2) MX379066B (enExample)
RU (1) RU2670749C9 (enExample)
SG (1) SG11201502104YA (enExample)
WO (1) WO2014047221A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
BR112015004110A2 (pt) 2012-08-31 2017-07-04 Taris Biomedical Llc sistemas e métodos de distribuição de drogas para tratamento de próstata
SI2890384T1 (sl) 2012-08-31 2022-02-28 Taris Biomedical Llc Sistemi za dostavo zdravila in postopki za zdravljenje raka sečnega mehurja, ki obsegajo oksaliplatin
SG11201502104YA (en) * 2012-09-18 2015-05-28 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder voiding dysfunction and other lower urinary tract disorders by using trospium
US20150250717A1 (en) 2014-03-06 2015-09-10 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine
WO2016028774A1 (en) * 2014-08-19 2016-02-25 The Regents Of The University Of California Implants for localized drug delivery and methods of use thereof
GB201506526D0 (en) 2015-04-17 2015-06-03 Uropharma Ltd And Synesis Llc Medicinal composition
CN106706832A (zh) * 2015-08-06 2017-05-24 舒泰神(北京)生物制药股份有限公司 一种测定曲司氯铵含量的方法
SMT202100310T1 (it) 2017-02-01 2021-07-12 Taris Biomedical Llc Dispositivi per la deposizione di farmaci in vivo
US10857173B2 (en) 2017-07-25 2020-12-08 Taris Biomedical Llc Methods of treating tumor metastasis
JOP20200124A1 (ar) 2017-11-08 2020-05-20 Taris Biomedical Llc طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體-藥物共軛物的組合治療癌症之方法
JP7460608B2 (ja) 2018-05-07 2024-04-02 ジェンマブ エー/エス 抗pd-1抗体と抗組織因子抗体-薬物コンジュゲートとの組み合わせを用いるがんの治療方法
KR20210039403A (ko) 2018-08-01 2021-04-09 타리스 바이오메디컬 엘엘씨 트로스피움을 사용한 과민성 방광의 치료 방법
TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子(vegf)抗體與抗組織因子(tf)抗體-藥物共軛體之組合以治療癌症之方法
EP3962449A1 (en) * 2019-04-30 2022-03-09 Trigone Pharma Ltd Formulations and methods for drug instillation into the bladder and treatment of bladder ailments
CA3171976A1 (en) 2020-03-20 2021-09-23 Carlos Schuler Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
KR102596697B1 (ko) 2021-05-20 2023-11-01 김정우 바위솔 추출물을 유효성분으로 포함하는 화장품 조성물 및 그 제조 방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998430A (en) * 1996-11-27 1999-12-07 Dr. R. Pfleger Chemische Fabrik Gmbh Use of trospium chloride and 2-component system for the same
WO2006101954A2 (en) * 2005-03-17 2006-09-28 Indevus Pharmaceuticals, Inc. Interstitial cystitis treatment
EA009781B1 (ru) * 2002-11-27 2008-04-28 Бёрингер Ингельхайм Интернациональ Гмбх Фармацевтическая композиция и ее применение для лечения нарушений функции мочевого пузыря
US20120203203A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled dissolution and diffusion of low solubility drug

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060058777A1 (en) * 2002-12-11 2006-03-16 Pia Norup Nielsen Urinary catheter device with a pharmaceutically active composition
CA2513188A1 (en) 2003-01-16 2004-08-05 University Of Rochester Quaternary antimuscarinic compounds for the treatment of bladder diseases
ES2322148T3 (es) 2004-08-11 2009-06-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias.
US7390816B2 (en) 2005-06-21 2008-06-24 Bridge Pharma, Inc. Methods for treating urinary incontinence in patients suffering from memory disorders
JP5265359B2 (ja) 2005-08-11 2013-08-14 マサチューセッツ インスティテュート オブ テクノロジー 膀胱内薬物送達デバイスおよび方法
EP1967202A1 (en) 2007-03-05 2008-09-10 AEterna Zentaris GmbH Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity
US9586035B2 (en) 2007-12-11 2017-03-07 Massachusetts Institute Of Technology Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
EA201170297A1 (ru) 2008-08-09 2011-08-30 Массачусетс Инститьют Оф Текнолоджи Имплантируемое устройство для доставки лекарственных средств и способ лечения мужской мочеполовой системы и окружающих тканей
AU2010265863C1 (en) 2009-06-26 2012-11-01 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
AU2010339821B2 (en) 2009-12-17 2015-02-19 Taris Biomedical Llc Implantable device with intravesical tolerability and methods of treatment
US20110218488A1 (en) 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
JP5945544B2 (ja) * 2010-10-06 2016-07-05 タリス バイオメディカル エルエルシー 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法
WO2012048104A1 (en) 2010-10-06 2012-04-12 Taris Biomedical, Inc. Implantable drug delivery device with bladden retention feature
CA2823783C (en) 2011-01-10 2023-03-21 Taris Biomedical, Inc. Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding
SG11201502104YA (en) * 2012-09-18 2015-05-28 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder voiding dysfunction and other lower urinary tract disorders by using trospium
HUE072250T2 (hu) 2013-03-15 2025-11-28 Taris Biomedical Llc Gyógyszeradagoló eszközök gyógyszeráteresztõ résszel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998430A (en) * 1996-11-27 1999-12-07 Dr. R. Pfleger Chemische Fabrik Gmbh Use of trospium chloride and 2-component system for the same
EA009781B1 (ru) * 2002-11-27 2008-04-28 Бёрингер Ингельхайм Интернациональ Гмбх Фармацевтическая композиция и ее применение для лечения нарушений функции мочевого пузыря
WO2006101954A2 (en) * 2005-03-17 2006-09-28 Indevus Pharmaceuticals, Inc. Interstitial cystitis treatment
US20120203203A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled dissolution and diffusion of low solubility drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VON WALTER M et al. "230 trospium chloride released from intravesically applied PLGA-based carriers decreased bladder contractility in an isolated whole pig bladder model"// European urology supplement, 01.03.2009, vol. 8, No 4, p. 178. *

Also Published As

Publication number Publication date
RU2015112196A (ru) 2016-11-10
CA2883855C (en) 2020-09-15
WO2014047221A9 (en) 2015-05-21
MX379066B (es) 2025-03-04
JP2015529688A (ja) 2015-10-08
US20200108057A1 (en) 2020-04-09
KR20150058271A (ko) 2015-05-28
WO2014047221A1 (en) 2014-03-27
AU2013318146A1 (en) 2015-03-19
IL237498B (en) 2018-01-31
JP2018080208A (ja) 2018-05-24
EP2897616A1 (en) 2015-07-29
CA2883855A1 (en) 2014-03-27
JP6600256B2 (ja) 2019-10-30
MX2020002465A (es) 2020-07-13
RU2670749C2 (ru) 2018-10-25
CN111450093A (zh) 2020-07-28
SG11201502104YA (en) 2015-05-28
AU2013318146B2 (en) 2018-05-10
US10500200B2 (en) 2019-12-10
CN104684556A (zh) 2015-06-03
KR102141433B1 (ko) 2020-08-05
IL237498A0 (en) 2015-04-30
MX2015003110A (es) 2015-06-05
US11850244B2 (en) 2023-12-26
BR112015005351A2 (pt) 2017-07-04
US20150182516A1 (en) 2015-07-02

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