JP6600256B2 - トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法 - Google Patents

トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法 Download PDF

Info

Publication number
JP6600256B2
JP6600256B2 JP2015532177A JP2015532177A JP6600256B2 JP 6600256 B2 JP6600256 B2 JP 6600256B2 JP 2015532177 A JP2015532177 A JP 2015532177A JP 2015532177 A JP2015532177 A JP 2015532177A JP 6600256 B2 JP6600256 B2 JP 6600256B2
Authority
JP
Japan
Prior art keywords
trospium
bladder
day
drug
treatment period
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015532177A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015529688A (ja
JP2015529688A5 (enExample
Inventor
ギーシング,デニス
Original Assignee
タリス バイオメディカル エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by タリス バイオメディカル エルエルシー filed Critical タリス バイオメディカル エルエルシー
Publication of JP2015529688A publication Critical patent/JP2015529688A/ja
Publication of JP2015529688A5 publication Critical patent/JP2015529688A5/ja
Application granted granted Critical
Publication of JP6600256B2 publication Critical patent/JP6600256B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
JP2015532177A 2012-09-18 2013-09-18 トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法 Active JP6600256B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702576P 2012-09-18 2012-09-18
US61/702,576 2012-09-18
PCT/US2013/060479 WO2014047221A1 (en) 2012-09-18 2013-09-18 Drug delivery systems and methods for treatment of bladder voiding dysfunction|and other lower urinary tract disorders by using trospium

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018017300A Division JP2018080208A (ja) 2012-09-18 2018-02-02 トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法

Publications (3)

Publication Number Publication Date
JP2015529688A JP2015529688A (ja) 2015-10-08
JP2015529688A5 JP2015529688A5 (enExample) 2019-06-13
JP6600256B2 true JP6600256B2 (ja) 2019-10-30

Family

ID=49301639

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015532177A Active JP6600256B2 (ja) 2012-09-18 2013-09-18 トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法
JP2018017300A Pending JP2018080208A (ja) 2012-09-18 2018-02-02 トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018017300A Pending JP2018080208A (ja) 2012-09-18 2018-02-02 トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法

Country Status (13)

Country Link
US (2) US10500200B2 (enExample)
EP (1) EP2897616A1 (enExample)
JP (2) JP6600256B2 (enExample)
KR (1) KR102141433B1 (enExample)
CN (2) CN111450093A (enExample)
AU (1) AU2013318146B2 (enExample)
BR (1) BR112015005351A2 (enExample)
CA (1) CA2883855C (enExample)
IL (1) IL237498B (enExample)
MX (2) MX379066B (enExample)
RU (1) RU2670749C9 (enExample)
SG (1) SG11201502104YA (enExample)
WO (1) WO2014047221A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
KR102383496B1 (ko) 2012-08-31 2022-04-08 타리스 바이오메디컬 엘엘씨 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법
RU2657591C2 (ru) 2012-08-31 2018-06-14 ТАРИС Биомедикал ЛЛК Способ лечения рака мочевого пузыря оксалиплатином, соответствующее устройство его доставки, способ и устройство его введения
MX379066B (es) * 2012-09-18 2025-03-04 Taris Biomedical Llc Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior.
CN106573133B (zh) * 2014-08-19 2020-03-03 加利福尼亚大学董事会 用于局部药物递送的植入物及其使用方法
GB201506526D0 (en) 2015-04-17 2015-06-03 Uropharma Ltd And Synesis Llc Medicinal composition
CN106706832A (zh) * 2015-08-06 2017-05-24 舒泰神(北京)生物制药股份有限公司 一种测定曲司氯铵含量的方法
LT3432970T (lt) 2017-02-01 2021-05-10 Taris Biomedical Llc In vivo vaistų vartojimo įtaisai
WO2019023388A1 (en) 2017-07-25 2019-01-31 Taris Biomedical Llc METHODS OF TREATING TUMOR METASTASIS
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體-藥物共軛物的組合治療癌症之方法
UA130009C2 (uk) 2018-05-07 2025-10-15 Генмаб А/С Спосіб лікування раку за допомогою комбінації антитіла до pd-1 і кон'югата антитіла до тканинного фактора і лікарського засобу
CA3107461A1 (en) * 2018-08-01 2020-02-06 Taris Biomedical Llc Methods of treating overactive bladder using trospium
TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子(vegf)抗體與抗組織因子(tf)抗體-藥物共軛體之組合以治療癌症之方法
WO2020222139A1 (en) * 2019-04-30 2020-11-05 Trigone Pharma Ltd. Formulations and methods for drug instillation into the bladder and treatment of bladder ailments
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
KR102596697B1 (ko) 2021-05-20 2023-11-01 김정우 바위솔 추출물을 유효성분으로 포함하는 화장품 조성물 및 그 제조 방법

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125696T3 (es) * 1996-11-27 1999-03-01 Pfleger R Chem Fab Utilizacion del cloruro de tropsio para la produccion de una preparacion farmaceutica para el tratamiento de disfunciones vesicales.
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
WO2004052440A1 (en) * 2002-12-11 2004-06-24 Coloplast A/S A urinary catheter device with a pharmaceutically active composition
AU2004206846B2 (en) 2003-01-16 2009-05-28 University Of Rochester Quaternary antimuscarinic compounds for the treatment of bladder diseases
ES2322148T3 (es) 2004-08-11 2009-06-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias.
US20060217405A1 (en) * 2005-03-17 2006-09-28 Indevus Pharmaceuticals, Inc. Interstitial cystitis treatment
US7390816B2 (en) 2005-06-21 2008-06-24 Bridge Pharma, Inc. Methods for treating urinary incontinence in patients suffering from memory disorders
US20100003297A1 (en) 2005-08-11 2010-01-07 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods of Treating Male Genitourinary and Surrounding Tissues
DK1933810T3 (da) 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
EP1967202A1 (en) 2007-03-05 2008-09-10 AEterna Zentaris GmbH Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity
DK2231254T3 (da) 2007-12-11 2014-07-21 Massachusetts Inst Technology Implanterbar lægemiddelafgivelsesindretning
US8343516B2 (en) 2009-06-26 2013-01-01 Taris Biomedical, Inc. Solid drug tablets for implantable drug delivery devices
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
US8679094B2 (en) 2009-12-17 2014-03-25 Taris Biomedical, Inc. Implantable device with intravesical tolerability and methods of treatment
US20110218488A1 (en) 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
US9457176B2 (en) 2010-10-06 2016-10-04 Taris Biomedical Llc Implantable drug delivery device with bladder retention feature
US8690840B2 (en) 2010-10-06 2014-04-08 Taris Biomedical, Inc. Time-selective bioresorbable or collapsible drug delivery systems and methods
US9114111B2 (en) 2011-01-10 2015-08-25 Allergan, Inc. Methods for sustained treatment of bladder pain and irritative voiding
WO2012106714A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
MX379066B (es) * 2012-09-18 2025-03-04 Taris Biomedical Llc Sistemas de administracion de farmaco y metodos para el tratamiento de la disfuncion miccional de la vejiga y otros trastornos del tracto urinario inferior.
SG11201507294WA (en) 2013-03-15 2015-10-29 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods

Also Published As

Publication number Publication date
CA2883855A1 (en) 2014-03-27
KR102141433B1 (ko) 2020-08-05
US11850244B2 (en) 2023-12-26
MX379066B (es) 2025-03-04
JP2015529688A (ja) 2015-10-08
CA2883855C (en) 2020-09-15
WO2014047221A9 (en) 2015-05-21
AU2013318146B2 (en) 2018-05-10
MX2020002465A (es) 2020-07-13
AU2013318146A1 (en) 2015-03-19
SG11201502104YA (en) 2015-05-28
WO2014047221A1 (en) 2014-03-27
RU2670749C9 (ru) 2018-12-13
CN111450093A (zh) 2020-07-28
US10500200B2 (en) 2019-12-10
KR20150058271A (ko) 2015-05-28
US20200108057A1 (en) 2020-04-09
EP2897616A1 (en) 2015-07-29
RU2670749C2 (ru) 2018-10-25
MX2015003110A (es) 2015-06-05
IL237498B (en) 2018-01-31
CN104684556A (zh) 2015-06-03
RU2015112196A (ru) 2016-11-10
US20150182516A1 (en) 2015-07-02
JP2018080208A (ja) 2018-05-24
IL237498A0 (en) 2015-04-30
BR112015005351A2 (pt) 2017-07-04

Similar Documents

Publication Publication Date Title
JP6600256B2 (ja) トロスピウムの使用による膀胱排尿機能障害及び他の下部尿路疾患の治療のための薬物送達システム及び方法
KR102157548B1 (ko) 방광암의 치료를 위한 옥살리플라틴을 포함하는 약물 전달 시스템과 방법
KR102383496B1 (ko) 젬시타빈을 포함하는 전립선 질환의 치료를 위한 약물 전달 시스템과 방법
HK40026424A (en) Drug delivery systems and methods for treatment of bladder voiding dysfunction and other lower urinary tract disorders by using trospium
HK40042011A (en) Drug delivery systems and methods for treatment of prostate

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160722

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170406

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170704

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20171003

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180202

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20180411

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20180511

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20190425

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20191004

R150 Certificate of patent or registration of utility model

Ref document number: 6600256

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250