CN111450093A - 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 - Google Patents

通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 Download PDF

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Publication number
CN111450093A
CN111450093A CN202010161062.6A CN202010161062A CN111450093A CN 111450093 A CN111450093 A CN 111450093A CN 202010161062 A CN202010161062 A CN 202010161062A CN 111450093 A CN111450093 A CN 111450093A
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CN
China
Prior art keywords
trospium
bladder
drug
day
drug delivery
Prior art date
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Pending
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CN202010161062.6A
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English (en)
Chinese (zh)
Inventor
丹尼斯·吉辛
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Taris Biomedical LLC
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Taris Biomedical LLC
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Filing date
Publication date
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Publication of CN111450093A publication Critical patent/CN111450093A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
CN202010161062.6A 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法 Pending CN111450093A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702576P 2012-09-18 2012-09-18
US61/702,576 2012-09-18
CN201380046758.2A CN104684556A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Related Parent Applications (1)

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CN201380046758.2A Division CN104684556A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

Publications (1)

Publication Number Publication Date
CN111450093A true CN111450093A (zh) 2020-07-28

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CN202010161062.6A Pending CN111450093A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法
CN201380046758.2A Pending CN104684556A (zh) 2012-09-18 2013-09-18 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法

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Country Status (13)

Country Link
US (2) US10500200B2 (enExample)
EP (1) EP2897616A1 (enExample)
JP (2) JP6600256B2 (enExample)
KR (1) KR102141433B1 (enExample)
CN (2) CN111450093A (enExample)
AU (1) AU2013318146B2 (enExample)
BR (1) BR112015005351A2 (enExample)
CA (1) CA2883855C (enExample)
IL (1) IL237498B (enExample)
MX (2) MX379066B (enExample)
RU (1) RU2670749C9 (enExample)
SG (1) SG11201502104YA (enExample)
WO (1) WO2014047221A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
BR112015004110A2 (pt) 2012-08-31 2017-07-04 Taris Biomedical Llc sistemas e métodos de distribuição de drogas para tratamento de próstata
SG11201501424SA (en) 2012-08-31 2015-03-30 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer comprising oxaliplatin
CN111450093A (zh) * 2012-09-18 2020-07-28 塔里斯生物医药公司 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法
EP3597176A1 (en) 2014-08-19 2020-01-22 The Regents Of The University Of California Implants for localized drug delivery and methods of use thereof
GB201506526D0 (en) 2015-04-17 2015-06-03 Uropharma Ltd And Synesis Llc Medicinal composition
CN106706832A (zh) * 2015-08-06 2017-05-24 舒泰神(北京)生物制药股份有限公司 一种测定曲司氯铵含量的方法
SI3432970T1 (sl) * 2017-02-01 2021-11-30 Taris Biomedical Llc Naprave za dovajanje zdravila IN VIVO
JP7391009B2 (ja) 2017-07-25 2023-12-04 タリス バイオメディカル エルエルシー 腫瘍転移を処置する方法
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體-藥物共軛物的組合治療癌症之方法
CN112739716B (zh) 2018-05-07 2025-05-27 展马博联合股份有限公司 使用抗pd-1抗体与抗组织因子抗体-药物偶联物的组合治疗癌症的方法
MX2021001264A (es) * 2018-08-01 2021-07-02 Taris Biomedical Llc Métodos para tratar la vejiga hiperactiva con el uso de trospio.
TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子(vegf)抗體與抗組織因子(tf)抗體-藥物共軛體之組合以治療癌症之方法
CN113939277B (zh) * 2019-04-30 2024-04-09 特瑞纲制药有限公司 用于药物输注到膀胱中和治疗膀胱疾病的制剂和方法
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
KR102596697B1 (ko) 2021-05-20 2023-11-01 김정우 바위솔 추출물을 유효성분으로 포함하는 화장품 조성물 및 그 제조 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060217405A1 (en) * 2005-03-17 2006-09-28 Indevus Pharmaceuticals, Inc. Interstitial cystitis treatment
CN101896221A (zh) * 2007-12-11 2010-11-24 麻省理工学院 用于治疗膀胱和其它体囊或体腔的可植入式药物递送设备和方法
US20120203203A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled dissolution and diffusion of low solubility drug

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59600683D1 (de) * 1996-11-27 1998-11-19 Pfleger R Chem Fab Verwendung von Trospiumchlorid zur Herstellung eines Arzneimittels zur Behandlung von Blasenkrankheiten
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
WO2004052440A1 (en) * 2002-12-11 2004-06-24 Coloplast A/S A urinary catheter device with a pharmaceutically active composition
US8481518B2 (en) 2003-01-16 2013-07-09 University Of Rochester Quaternary antimuscarinic compounds for the treatment of bladder diseases
DE602004020337D1 (de) 2004-08-11 2009-05-14 Boehringer Ingelheim Pharma Anticholinergika enthaltende Arzneimittel zur Behandlung von Krankheiten der ableitenden Harnwege
US7390816B2 (en) 2005-06-21 2008-06-24 Bridge Pharma, Inc. Methods for treating urinary incontinence in patients suffering from memory disorders
JP5265359B2 (ja) 2005-08-11 2013-08-14 マサチューセッツ インスティテュート オブ テクノロジー 膀胱内薬物送達デバイスおよび方法
EP1967202A1 (en) 2007-03-05 2008-09-10 AEterna Zentaris GmbH Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity
CA2733468C (en) 2008-08-09 2017-12-05 Massachusetts Institute Of Technology Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues
CA2765734C (en) 2009-06-26 2016-12-13 Taris Biomedical, Inc. Implantable drug delivery devices and methods of making the same
US8721621B2 (en) 2009-09-10 2014-05-13 Taris Biomedical, Inc. Systems and methods for deploying devices to genitourinary sites
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
LT2512581T (lt) 2009-12-17 2021-03-25 Taris Biomedical Llc Intravezikalinio suderinamumo implantuojamas medicininis įtaisas
US20110218488A1 (en) 2010-03-05 2011-09-08 Taris Biomedical, Inc. Systems and Methods for Implanting Devices in the Bladder and Other Genitourinary Sites
US9457176B2 (en) 2010-10-06 2016-10-04 Taris Biomedical Llc Implantable drug delivery device with bladder retention feature
JP5945544B2 (ja) 2010-10-06 2016-07-05 タリス バイオメディカル エルエルシー 時間選択的に生体吸収可能または崩壊可能な薬剤送達システムおよび方法
JP2014503554A (ja) 2011-01-10 2014-02-13 タリス バイオメディカル,インコーポレイテッド 膀胱痛及び刺激性排尿の持続的治療の使用のためのリドカインレジメン
CN111450093A (zh) * 2012-09-18 2020-07-28 塔里斯生物医药公司 通过使用曲司铵来治疗膀胱排尿功能障碍和其它下泌尿道病症的药物递送系统和方法
KR102398262B1 (ko) 2013-03-15 2022-05-13 타리스 바이오메디컬 엘엘씨 약물-투과성 구성요소를 가지는 약물 전달 장치 및 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060217405A1 (en) * 2005-03-17 2006-09-28 Indevus Pharmaceuticals, Inc. Interstitial cystitis treatment
CN101896221A (zh) * 2007-12-11 2010-11-24 麻省理工学院 用于治疗膀胱和其它体囊或体腔的可植入式药物递送设备和方法
US20120203203A1 (en) * 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled dissolution and diffusion of low solubility drug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VON WALTER M等: "Trospium chloride released from intravesically applied PLGA-based carriers decreases bladder contractility in an isolated whole pig bladder model", 《EUROPEAN UROLOGY SUPPLEMENTS》 *

Also Published As

Publication number Publication date
AU2013318146A1 (en) 2015-03-19
JP2018080208A (ja) 2018-05-24
BR112015005351A2 (pt) 2017-07-04
SG11201502104YA (en) 2015-05-28
RU2015112196A (ru) 2016-11-10
CA2883855C (en) 2020-09-15
JP2015529688A (ja) 2015-10-08
MX379066B (es) 2025-03-04
US20200108057A1 (en) 2020-04-09
WO2014047221A9 (en) 2015-05-21
EP2897616A1 (en) 2015-07-29
US10500200B2 (en) 2019-12-10
MX2015003110A (es) 2015-06-05
IL237498B (en) 2018-01-31
KR20150058271A (ko) 2015-05-28
RU2670749C9 (ru) 2018-12-13
US11850244B2 (en) 2023-12-26
WO2014047221A1 (en) 2014-03-27
AU2013318146B2 (en) 2018-05-10
CA2883855A1 (en) 2014-03-27
CN104684556A (zh) 2015-06-03
KR102141433B1 (ko) 2020-08-05
US20150182516A1 (en) 2015-07-02
JP6600256B2 (ja) 2019-10-30
RU2670749C2 (ru) 2018-10-25
IL237498A0 (en) 2015-04-30
MX2020002465A (es) 2020-07-13

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