RU2666601C2 - Стабилизирующая композиция для биологических материалов - Google Patents

Стабилизирующая композиция для биологических материалов Download PDF

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RU2666601C2
RU2666601C2 RU2014136089A RU2014136089A RU2666601C2 RU 2666601 C2 RU2666601 C2 RU 2666601C2 RU 2014136089 A RU2014136089 A RU 2014136089A RU 2014136089 A RU2014136089 A RU 2014136089A RU 2666601 C2 RU2666601 C2 RU 2666601C2
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composition
protein
dry
acid
drying
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RU2014136089A
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RU2014136089A (ru
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Моти ХАРЕЛ
Кён ТАН
Триша РАЙС
Кимберли ДЖЕННИНГС
Брайан КАРПЕНТЕР
Роджер ДРЮС
Элизабет РЭДИТСИС
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Эдванст Бионутришн Корп.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/30—Puffing or expanding
    • A23P30/32—Puffing or expanding by pressure release, e.g. explosion puffing; by vacuum treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Animal Husbandry (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Fodder In General (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2014136089A 2012-03-23 2013-03-22 Стабилизирующая композиция для биологических материалов RU2666601C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261614994P 2012-03-23 2012-03-23
US61/614,994 2012-03-23
US201261642094P 2012-05-03 2012-05-03
US61/642,094 2012-05-03
US201261646337P 2012-05-13 2012-05-13
US61/646,337 2012-05-13
PCT/US2013/033505 WO2013142792A1 (en) 2012-03-23 2013-03-22 Stabilizing composition for biological materials

Publications (2)

Publication Number Publication Date
RU2014136089A RU2014136089A (ru) 2016-05-20
RU2666601C2 true RU2666601C2 (ru) 2018-09-11

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EP (1) EP2827905B1 (https=)
JP (1) JP6229188B2 (https=)
KR (1) KR102062645B1 (https=)
CN (2) CN104244985A (https=)
AR (1) AR093204A1 (https=)
AU (1) AU2013234931B2 (https=)
BR (1) BR112014023234B1 (https=)
CA (1) CA2866889C (https=)
CL (1) CL2014002506A1 (https=)
ES (1) ES3016483T3 (https=)
IN (1) IN2014DN08599A (https=)
MX (1) MX356072B (https=)
MY (1) MY178686A (https=)
NZ (1) NZ628912A (https=)
PH (1) PH12014502092B1 (https=)
RU (1) RU2666601C2 (https=)
SG (1) SG11201405478VA (https=)
WO (1) WO2013142792A1 (https=)

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RU2736064C1 (ru) * 2020-04-03 2020-11-11 Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации Защитная среда для стабилизации клеток возбудителя туляремии в процессе приготовления и хранения сухих препаратов
RU2806114C2 (ru) * 2022-04-21 2023-10-26 Общество С Ограниченной Ответственностью "Кинетик-Фарм" Средство для интравагинальной доставки активного компонента, способ получения и применения средства
WO2023204734A1 (ru) * 2022-04-21 2023-10-26 Общество С Ограниченной Ответственностью "Кинетик-Фарм" Средство для интравагинальной доставки активного компонента, способ получения и применения средства

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US20140255583A1 (en) * 2013-03-06 2014-09-11 Sunny Delight Beverages Company Protein suspension as a beverage opacifier system
MX376352B (es) 2013-10-25 2025-03-07 Nch Corp Sistema de suministro y composicion probiotica para animales y plantas.
US10610552B2 (en) 2016-04-05 2020-04-07 Nch Corporation Nutrient rich germinant composition and spore incubation method
US10766799B2 (en) 2014-05-23 2020-09-08 Nch Corporation Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method
KR102567744B1 (ko) * 2015-02-11 2023-08-18 에바 뉴트리션 인크 생존 가능한 대장균을 삽입하기 위한 향상된 건조 기질, 이의 제조 방법 및 용도
JP6889699B2 (ja) 2015-07-29 2021-06-18 アドバンスド バイオニュートリション コープ． 特定栄養用途のための安定乾燥プロバイオティクス組成物
US12558395B2 (en) 2015-07-29 2026-02-24 Advanced Bionutrition Corp. Stable dry probiotic compositions for special dietary uses
AU2016365214B2 (en) 2015-12-04 2021-02-25 Advanced Bionutrition Corp. Stable dry compositions having no or little sugars
FR3045384B1 (fr) * 2015-12-18 2020-02-07 Institut National De La Recherche Agronomique Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
MX377224B (es) * 2015-12-18 2025-03-07 Soc Des Produits Nestle S A Star Hidratacion para animales.
CN105504050A (zh) * 2016-03-03 2016-04-20 河南欧普生物科技有限公司 一种抗安卡拉病毒鸡卵黄抗体的制备方法
US10897922B2 (en) 2016-04-05 2021-01-26 Nch Corporation Composition and method for germinative compounds in probiotic food and beverage products for human consumption
US12097226B2 (en) 2016-04-05 2024-09-24 Nch Corporation System and method for using a single-serve nutrient spore composition for small scale farm applications
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EP3476226B1 (en) 2016-06-24 2024-05-22 Yessinergy Holding s/a Immunomodulating and growth-promoting composition controlling the population of undesirable bacteria in the intestinal microbiota
KR101766430B1 (ko) * 2016-10-28 2017-08-08 주식회사 삼양사 올리고당을 함유하는 알룰로오스 시럽 및 그 제조방법
CN106819418A (zh) * 2017-03-27 2017-06-13 张军军 一种超高脂饲料及其制备方法
US10323226B2 (en) * 2017-03-30 2019-06-18 Nch Corporation Feed material for biomass generator
GB201708932D0 (en) * 2017-06-05 2017-07-19 Probi Ab Microbial compositions
US12377124B2 (en) 2018-07-04 2025-08-05 Chr. Hansen A/S Topical compositions comprising viable probiotic bacteria
US20210275613A1 (en) * 2018-07-04 2021-09-09 Chr. Hansen A/S Aqueous topical compositions comprising viable probiotic bacteria
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications
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WO2020130770A1 (es) * 2018-12-19 2020-06-25 Ajtzakbio S.A.P.I. De C.V. Composición probiótica de alto valor sin necesidad de cadena de frio, desarrollada para reducir el impacto ambiental, aumentar la producción y mejorar la supervivencia de larvas de camarón
WO2021055352A1 (en) * 2019-09-16 2021-03-25 Vedanta Biosciences, Inc. Methods and compositions for preserving bacteria
WO2021081018A1 (en) * 2019-10-22 2021-04-29 Massachusetts Institute Of Technology Biomaterial-based compositions to deliver plant growth promoting microbes
CN110923145B (zh) * 2019-12-16 2021-07-20 天康制药(苏州)有限公司 支原体的冻干保护剂与冻干支原体及其制备方法
US11576937B2 (en) 2020-02-06 2023-02-14 Nch Corporation Method of reducing gut inflammation reduction in humans by consuming a heated probiotic composition
US20230080017A1 (en) * 2020-02-19 2023-03-16 Zantebio Limited Coated microcapsules and methods for the production thereof
RU2746022C1 (ru) * 2020-04-03 2021-04-06 Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации Способ стабилизации бактериальных клеток чумного микроба перед сублимационным высушиванием
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WO2022171617A1 (en) * 2021-02-10 2022-08-18 Dsm Ip Assets B.V. Powderous composition (i)
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CN117256857B (zh) * 2023-07-24 2025-12-02 浙江大学 一种用于制备鱼油微胶囊的复合壁材及其制备方法与应用
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CN117247305A (zh) * 2023-09-16 2023-12-19 鲁东大学 一种促进植物根系生长的水凝胶及制备方法

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