RU2659936C2 - Активация прокаспазы-3 с помощью комбинированной терапии - Google Patents

Активация прокаспазы-3 с помощью комбинированной терапии Download PDF

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RU2659936C2
RU2659936C2 RU2014139954A RU2014139954A RU2659936C2 RU 2659936 C2 RU2659936 C2 RU 2659936C2 RU 2014139954 A RU2014139954 A RU 2014139954A RU 2014139954 A RU2014139954 A RU 2014139954A RU 2659936 C2 RU2659936 C2 RU 2659936C2
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active agent
cancer
pac
cells
concentration
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RU2014139954A
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RU2014139954A (ru
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Пол Дж. Хергенротер
Рейчел Си. Ботэм
Тимоти М. ФЭН
Марк Дж. Гилберт
Майкл К. Хендли
Теодор М. ТАРАСОВ
Говард Эс. РОТ
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Зэ Борд оф Трастиз оф зэ Юниверсити оф Иллинойс
Ванкуиш Онколоджи, Инк.
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  • Pulmonology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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RU2014139954A 2012-03-06 2013-03-06 Активация прокаспазы-3 с помощью комбинированной терапии RU2659936C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261607098P 2012-03-06 2012-03-06
US61/607,098 2012-03-06
PCT/US2013/029405 WO2013134407A2 (en) 2012-03-06 2013-03-06 Procaspase 3 activation by combination therapy

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Publication Number Publication Date
RU2014139954A RU2014139954A (ru) 2016-04-27
RU2659936C2 true RU2659936C2 (ru) 2018-07-04

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US (4) US9399035B2 (OSRAM)
EP (2) EP2822558B1 (OSRAM)
JP (1) JP6172865B2 (OSRAM)
KR (1) KR102074530B1 (OSRAM)
CN (1) CN104507479B (OSRAM)
AU (1) AU2016213862B2 (OSRAM)
BR (1) BR112014022103B1 (OSRAM)
CA (1) CA2866021C (OSRAM)
DK (1) DK2822558T3 (OSRAM)
ES (1) ES2774930T3 (OSRAM)
IN (1) IN2014MN01945A (OSRAM)
MX (2) MX365392B (OSRAM)
RU (1) RU2659936C2 (OSRAM)
WO (2) WO2013134407A2 (OSRAM)

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WO2008134474A2 (en) 2007-04-27 2008-11-06 The Board Of Trustees Of The University Of Illinois Compositions and methods including cell death inducers and procaspase activation
KR102074530B1 (ko) 2012-03-06 2020-02-06 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 조합 요법에 의한 프로카스파제 ３ 활성화
CA2922575C (en) * 2013-11-01 2022-10-11 Newsouth Innovations Pty Limited Pharmaceutical combinations for the treatment of cancer
AU2015341700A1 (en) * 2014-11-07 2017-06-08 Lipoxen Technologies Limited Method for treatment of primary hormone resistant endometrial and breast cancers
WO2016090371A2 (en) 2014-12-05 2016-06-09 An2H Discovery Limited Parkin ligase activation methods and compositions
WO2016197129A1 (en) 2015-06-05 2016-12-08 The Board Of Trustees Of The University Of Illinois Pac-1 combination therapy
KR101712638B1 (ko) * 2015-08-19 2017-03-07 한국과학기술연구원 Pac-1을 이용한 단백질 발현 조절 시스템과 방법 및 pac-1을 유효성분 포함하는 독시사이클린 길항제
US10308617B2 (en) 2016-06-03 2019-06-04 An2H Discovery Limited Triazole benzamide derivatives and the compositions and methods of treatment regarding the same
IL274663B2 (en) * 2017-11-17 2024-01-01 Univ Illinois Cancer therapy by degrading dual mek signaling
US10889553B2 (en) 2017-12-01 2021-01-12 Nysnobio Ireland Dac Asymmetric triazole benzamide derivatives and the compositions and methods of treatment regarding the same
CA3114385A1 (en) * 2018-10-05 2020-04-09 The Board Of Trustees Of The University Of Illinois Combination therapy for the treatment of uveal melanoma
JP7648155B2 (ja) * 2019-05-30 2025-03-18 ザ ボード オブ トラスティーズ オブ ザ ユニバーシテイ オブ イリノイ プロカスパーゼ‐３の活性化及びがんの治療のための免疫療法

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