RU2659171C2 - Способ лечения лимфомы, применяя тиенотриазолодиазепиновые соединения - Google Patents
Способ лечения лимфомы, применяя тиенотриазолодиазепиновые соединения Download PDFInfo
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- RU2659171C2 RU2659171C2 RU2015101106A RU2015101106A RU2659171C2 RU 2659171 C2 RU2659171 C2 RU 2659171C2 RU 2015101106 A RU2015101106 A RU 2015101106A RU 2015101106 A RU2015101106 A RU 2015101106A RU 2659171 C2 RU2659171 C2 RU 2659171C2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261663885P | 2012-06-25 | 2012-06-25 | |
| US61/663,885 | 2012-06-25 | ||
| US201261670918P | 2012-07-12 | 2012-07-12 | |
| US61/670,918 | 2012-07-12 | ||
| PCT/EP2013/063313 WO2014001356A1 (en) | 2012-06-25 | 2013-06-25 | Method of treating lymphoma using thienotriazolodiazepine compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015101106A RU2015101106A (ru) | 2016-08-10 |
| RU2659171C2 true RU2659171C2 (ru) | 2018-06-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015101106A RU2659171C2 (ru) | 2012-06-25 | 2013-06-25 | Способ лечения лимфомы, применяя тиенотриазолодиазепиновые соединения |
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| Country | Link |
|---|---|
| US (1) | US20140018353A1 (enExample) |
| EP (1) | EP2863923B1 (enExample) |
| JP (1) | JP6265979B2 (enExample) |
| KR (1) | KR20150045423A (enExample) |
| CN (1) | CN105050605A (enExample) |
| AU (1) | AU2013283378B2 (enExample) |
| BR (1) | BR112014032105A2 (enExample) |
| CA (1) | CA2877434A1 (enExample) |
| IN (1) | IN2014DN11269A (enExample) |
| MX (1) | MX2014015986A (enExample) |
| RU (1) | RU2659171C2 (enExample) |
| WO (1) | WO2014001356A1 (enExample) |
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| EP2802608A4 (en) | 2012-01-12 | 2015-08-05 | Univ Yale | COMPOUNDS AND METHODS FOR ENHANCED DEGRADATION OF TARGET PROTEINS AND OTHER POLYPEPTIDES BY E3 UBIQUITIN LIGASE |
| KR102216288B1 (ko) | 2013-03-15 | 2021-02-18 | 인사이트 홀딩스 코포레이션 | Bet 단백질 저해제로서의 삼환식 복소환 |
| ES2635560T3 (es) | 2013-07-08 | 2017-10-04 | Incyte Holdings Corporation | Heterociclos tricíclicos como inhibidores de la proteína NET |
| US9795612B2 (en) * | 2013-08-01 | 2017-10-24 | Merck Sharp & Dohme Corp. | Pharmaceutical formulation containing thienotriazolodiazepine compounds |
| CN105899212A (zh) * | 2013-08-06 | 2016-08-24 | 翁科埃斯克斯有限公司 | 利用β溴结构域抑制剂治疗弥漫性大B细胞淋巴瘤(DLBCL)的方法 |
| WO2015018520A1 (en) * | 2013-08-06 | 2015-02-12 | Oncoethix Sa | A bet-brd inhibitor represents a novel agent for alk positive anaplastic large cell lymphoma |
| WO2015018522A1 (en) * | 2013-08-06 | 2015-02-12 | Oncoethix Sa | Bet-bromodomain inhibitor shows synergism with several anti-cancer agents in pre-clinical models of diffuse large b-cell lymphoma (dlbcl) |
| US9399640B2 (en) | 2013-11-26 | 2016-07-26 | Incyte Corporation | Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors |
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- 2013-06-25 BR BR112014032105A patent/BR112014032105A2/pt not_active Application Discontinuation
- 2013-06-25 IN IN11269DEN2014 patent/IN2014DN11269A/en unknown
- 2013-06-25 KR KR20157000782A patent/KR20150045423A/ko not_active Withdrawn
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Also Published As
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|---|---|
| US20140018353A1 (en) | 2014-01-16 |
| EP2863923B1 (en) | 2019-05-08 |
| MX2014015986A (es) | 2016-02-11 |
| CN105050605A (zh) | 2015-11-11 |
| BR112014032105A2 (pt) | 2017-08-01 |
| KR20150045423A (ko) | 2015-04-28 |
| WO2014001356A1 (en) | 2014-01-03 |
| AU2013283378B2 (en) | 2017-07-13 |
| CA2877434A1 (en) | 2014-01-03 |
| JP6265979B2 (ja) | 2018-01-24 |
| EP2863923A1 (en) | 2015-04-29 |
| AU2013283378A1 (en) | 2015-01-29 |
| JP2015531747A (ja) | 2015-11-05 |
| IN2014DN11269A (enExample) | 2015-10-09 |
| RU2015101106A (ru) | 2016-08-10 |
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