RU2658485C2 - Химерные антигенные рецепторы м971 - Google Patents

Химерные антигенные рецепторы м971 Download PDF

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RU2658485C2
RU2658485C2 RU2015117237A RU2015117237A RU2658485C2 RU 2658485 C2 RU2658485 C2 RU 2658485C2 RU 2015117237 A RU2015117237 A RU 2015117237A RU 2015117237 A RU2015117237 A RU 2015117237A RU 2658485 C2 RU2658485 C2 RU 2658485C2
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car
seq
cell
cancer
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RU2015117237A
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RU2015117237A (ru
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Римас Дж. ОРЕНТАС
Ира Х. ПАСТАН
Димитер С. ДИМИТРОВ
Кристал Л. МАККОЛЛ
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Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/42—Cancer antigens
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RU2015117237A 2012-10-24 2013-09-18 Химерные антигенные рецепторы м971 RU2658485C2 (ru)

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US201261717960P 2012-10-24 2012-10-24
US61/717,960 2012-10-24
PCT/US2013/060332 WO2014065961A1 (en) 2012-10-24 2013-09-18 M971 chimeric antigen receptors

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RU2658485C2 true RU2658485C2 (ru) 2018-06-21

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US (5) US10072078B2 (OSRAM)
EP (1) EP2912061B1 (OSRAM)
JP (2) JP6338252B2 (OSRAM)
CN (2) CN104822705B (OSRAM)
AU (2) AU2013335180B2 (OSRAM)
BR (1) BR112015009003B1 (OSRAM)
CA (1) CA2889055C (OSRAM)
ES (1) ES2718903T3 (OSRAM)
RU (2) RU2658485C2 (OSRAM)
WO (1) WO2014065961A1 (OSRAM)

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