RU2650859C2 - Способ ферментативного получения l-метионина из о-фосфо-l-гомосерина и метантиола - Google Patents

Способ ферментативного получения l-метионина из о-фосфо-l-гомосерина и метантиола Download PDF

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RU2650859C2
RU2650859C2 RU2015119400A RU2015119400A RU2650859C2 RU 2650859 C2 RU2650859 C2 RU 2650859C2 RU 2015119400 A RU2015119400 A RU 2015119400A RU 2015119400 A RU2015119400 A RU 2015119400A RU 2650859 C2 RU2650859 C2 RU 2650859C2
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methionine
amino acid
homoserine
seq
methanethiol
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RU2015119400A
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English (en)
Russian (ru)
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RU2015119400A (ru
Inventor
Мюриэль МЕРКАММ
Доминик ЛУИ
Карин ЖАЙАРДОН
Доминик ТОМА
Филипп Марльер
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Адиссео Франс С.А.С.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01048—Cystathionine gamma-synthase (2.5.1.48)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
RU2015119400A 2012-10-26 2013-10-25 Способ ферментативного получения l-метионина из о-фосфо-l-гомосерина и метантиола RU2650859C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12190150.8 2012-10-26
EP12190150 2012-10-26
PCT/EP2013/072380 WO2014064244A2 (en) 2012-10-26 2013-10-25 Means and methods for the enzymatic production of l-methionine from o-phospho-l-homoserine and methanethiol

Publications (2)

Publication Number Publication Date
RU2015119400A RU2015119400A (ru) 2016-12-20
RU2650859C2 true RU2650859C2 (ru) 2018-04-17

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RU2015119400A RU2650859C2 (ru) 2012-10-26 2013-10-25 Способ ферментативного получения l-метионина из о-фосфо-l-гомосерина и метантиола

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Country Link
US (1) US9803225B2 (enExample)
EP (1) EP2912185A2 (enExample)
JP (1) JP6438402B2 (enExample)
KR (1) KR102126318B1 (enExample)
CN (1) CN104755625B (enExample)
BR (1) BR112015007212B1 (enExample)
IN (1) IN2015DN02439A (enExample)
MY (1) MY176164A (enExample)
RU (1) RU2650859C2 (enExample)
WO (1) WO2014064244A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10382927B2 (en) * 2015-08-20 2019-08-13 Samsung Electronics Co., Ltd. Method of text input for wearable devices
EP3330380A1 (en) * 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional
US11162122B2 (en) 2017-07-11 2021-11-02 Adisseo France S.A.S. Methionine-producing yeast
KR102025867B1 (ko) * 2017-07-13 2019-09-27 씨제이제일제당 주식회사 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법
EP3875590A4 (en) * 2018-10-30 2023-02-15 Green Earth Institute Co., Ltd. PROCESS FOR THE PRODUCTION OF AN ORGANIC COMPOUND AND CORYNEFORM BACTERIUM
US20220315965A1 (en) * 2019-06-25 2022-10-06 Zymergen Inc. Engineered biosynthetic pathways for production of cystathionine by fermentation
KR102744891B1 (ko) 2022-03-24 2024-12-19 씨제이제일제당 주식회사 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법
JP2026508194A (ja) * 2023-03-01 2026-03-10 フーナン リアー バイオテック カンパニー リミテッド Ｌ－メチオニンをｌ－ホモセリンから直接調製するプロセス
CN117165549B (zh) * 2023-08-30 2026-08-11 天津科技大学 一种胱硫醚-γ-合酶突变体及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017112A1 (en) * 1992-02-20 1993-09-02 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
RU2447146C2 (ru) * 2005-07-18 2012-04-10 Эвоник Дегусса Гмбх Рекомбинантные микроорганизмы, продуцирующие метионин

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1846547A2 (en) * 2005-02-07 2007-10-24 Metabolic Explorer Microorganisms comprising enzymes expressed with low gamma-elimination activity
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017112A1 (en) * 1992-02-20 1993-09-02 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
RU2447146C2 (ru) * 2005-07-18 2012-04-10 Эвоник Дегусса Гмбх Рекомбинантные микроорганизмы, продуцирующие метионин

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
3, 03.10.2012. PAKULA A.A. ET AL. Genetic analysis of protein stability and function.// Annu. Rev. Genet. 1989. 23:289-310, см. с. 305-306. *
PAKULA A.A. ET AL. Genetic analysis of protein stability and function.// Annu. Rev. Genet. 1989. 23:289-310, см. с. 305-306. *
база данных GenBank:AAF74981.1, 10.06.2000. база данных UniProtKB/Swiss-Prot: P55217. *
база данных GenBank:AAF74981.1, 10.06.2000. база данных UniProtKB/Swiss-Prot: P55217.3, 03.10.2012. *

Also Published As

Publication number Publication date
KR20150076159A (ko) 2015-07-06
WO2014064244A3 (en) 2014-08-14
US9803225B2 (en) 2017-10-31
BR112015007212A2 (pt) 2018-01-30
JP2015533280A (ja) 2015-11-24
JP6438402B2 (ja) 2018-12-12
US20150275247A1 (en) 2015-10-01
IN2015DN02439A (enExample) 2015-09-04
KR102126318B1 (ko) 2020-06-25
MY176164A (en) 2020-07-24
CN104755625B (zh) 2020-02-07
CN104755625A (zh) 2015-07-01
WO2014064244A2 (en) 2014-05-01
RU2015119400A (ru) 2016-12-20
BR112015007212B1 (pt) 2022-07-05
EP2912185A2 (en) 2015-09-02

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