JP6438402B2 - O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 - Google Patents

O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 Download PDF

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JP6438402B2
JP6438402B2 JP2015538462A JP2015538462A JP6438402B2 JP 6438402 B2 JP6438402 B2 JP 6438402B2 JP 2015538462 A JP2015538462 A JP 2015538462A JP 2015538462 A JP2015538462 A JP 2015538462A JP 6438402 B2 JP6438402 B2 JP 6438402B2
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methionine
amino acid
homoserine
seq
phospho
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JP2015533280A (ja
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メルカム ミュリエル
メルカム ミュリエル
ルイ ドミニク
ルイ ドミニク
ジェラルドン カリン
ジェラルドン カリン
トマ ドミニク
トマ ドミニク
マルリエール フィリップ
マルリエール フィリップ
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Adisseo France SAS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01048—Cystathionine gamma-synthase (2.5.1.48)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
JP2015538462A 2012-10-26 2013-10-25 O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法 Active JP6438402B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12190150.8 2012-10-26
EP12190150 2012-10-26
PCT/EP2013/072380 WO2014064244A2 (en) 2012-10-26 2013-10-25 Means and methods for the enzymatic production of l-methionine from o-phospho-l-homoserine and methanethiol

Publications (2)

Publication Number Publication Date
JP2015533280A JP2015533280A (ja) 2015-11-24
JP6438402B2 true JP6438402B2 (ja) 2018-12-12

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JP2015538462A Active JP6438402B2 (ja) 2012-10-26 2013-10-25 O−ホスホ−l−ホモセリンおよびメタンチオールからl−メチオニンを酵素的に産生する手段および方法

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Country Link
US (1) US9803225B2 (enExample)
EP (1) EP2912185A2 (enExample)
JP (1) JP6438402B2 (enExample)
KR (1) KR102126318B1 (enExample)
CN (1) CN104755625B (enExample)
BR (1) BR112015007212B1 (enExample)
IN (1) IN2015DN02439A (enExample)
MY (1) MY176164A (enExample)
RU (1) RU2650859C2 (enExample)
WO (1) WO2014064244A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10382927B2 (en) * 2015-08-20 2019-08-13 Samsung Electronics Co., Ltd. Method of text input for wearable devices
EP3330380A1 (en) * 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional
US11162122B2 (en) 2017-07-11 2021-11-02 Adisseo France S.A.S. Methionine-producing yeast
KR102025867B1 (ko) * 2017-07-13 2019-09-27 씨제이제일제당 주식회사 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법
EP3875590A4 (en) * 2018-10-30 2023-02-15 Green Earth Institute Co., Ltd. PROCESS FOR THE PRODUCTION OF AN ORGANIC COMPOUND AND CORYNEFORM BACTERIUM
US20220315965A1 (en) * 2019-06-25 2022-10-06 Zymergen Inc. Engineered biosynthetic pathways for production of cystathionine by fermentation
KR102744891B1 (ko) 2022-03-24 2024-12-19 씨제이제일제당 주식회사 인산을 발효액 또는 발효 폐액으로부터 회수 및 재사용하는 방법
JP2026508194A (ja) * 2023-03-01 2026-03-10 フーナン リアー バイオテック カンパニー リミテッド L-メチオニンをl-ホモセリンから直接調製するプロセス
CN117165549B (zh) * 2023-08-30 2026-08-11 天津科技大学 一种胱硫醚-γ-合酶突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0630406A1 (en) * 1992-02-20 1994-12-28 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
EP1846547A2 (en) * 2005-02-07 2007-10-24 Metabolic Explorer Microorganisms comprising enzymes expressed with low gamma-elimination activity
KR20080036608A (ko) * 2005-07-18 2008-04-28 바스프 에스이 메티오닌 생산 재조합 미생물
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation

Also Published As

Publication number Publication date
KR20150076159A (ko) 2015-07-06
WO2014064244A3 (en) 2014-08-14
US9803225B2 (en) 2017-10-31
BR112015007212A2 (pt) 2018-01-30
JP2015533280A (ja) 2015-11-24
US20150275247A1 (en) 2015-10-01
RU2650859C2 (ru) 2018-04-17
IN2015DN02439A (enExample) 2015-09-04
KR102126318B1 (ko) 2020-06-25
MY176164A (en) 2020-07-24
CN104755625B (zh) 2020-02-07
CN104755625A (zh) 2015-07-01
WO2014064244A2 (en) 2014-05-01
RU2015119400A (ru) 2016-12-20
BR112015007212B1 (pt) 2022-07-05
EP2912185A2 (en) 2015-09-02

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