RU2642287C2 - Химерная частица hpv - Google Patents

Химерная частица hpv Download PDF

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RU2642287C2
RU2642287C2 RU2014126587A RU2014126587A RU2642287C2 RU 2642287 C2 RU2642287 C2 RU 2642287C2 RU 2014126587 A RU2014126587 A RU 2014126587A RU 2014126587 A RU2014126587 A RU 2014126587A RU 2642287 C2 RU2642287 C2 RU 2642287C2
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hpv
chimeric
polypeptide
seq
plant
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RU2014126587A
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RU2014126587A (ru
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Эдвард Питер РЫБИЦКИ
Инга Изабель ХИТЦЕРОТ
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Юниверсити Оф Кейп Таун
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/62DNA sequences coding for fusion proteins
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • C12N7/045Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
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    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/20023Virus like particles [VLP]
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    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

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  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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RU2014126587A 2011-12-01 2012-12-03 Химерная частица hpv RU2642287C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA2011/08841 2011-12-01
ZA201108841 2011-12-01
PCT/IB2012/056912 WO2013080187A1 (en) 2011-12-01 2012-12-03 Hpv chimaeric particle

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RU2014126587A RU2014126587A (ru) 2016-01-27
RU2642287C2 true RU2642287C2 (ru) 2018-01-24

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US (1) US9771397B2 (https=)
EP (1) EP2785842A4 (https=)
JP (1) JP6228922B2 (https=)
KR (1) KR102013801B1 (https=)
CN (1) CN103890177B (https=)
AU (1) AU2012345443B2 (https=)
BR (1) BR112014012491A2 (https=)
CA (1) CA2850293C (https=)
HK (1) HK1198703A1 (https=)
IL (1) IL232584B (https=)
IN (1) IN2014DN03054A (https=)
MX (1) MX355352B (https=)
MY (1) MY184076A (https=)
PH (1) PH12014500466A1 (https=)
RU (1) RU2642287C2 (https=)
SG (1) SG11201401579UA (https=)
WO (1) WO2013080187A1 (https=)
ZA (1) ZA201403557B (https=)

Cited By (2)

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RU2806424C2 (ru) * 2019-07-19 2023-10-31 Синоселлтех Лтд. Поливалентная иммуногенная композиция против папилломавируса человека
US12440549B2 (en) 2019-07-19 2025-10-14 Sinocelltech Ltd. Polyvalent immunogenicity composition for human papillomavirus

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EP3427755B1 (en) 2009-04-13 2020-10-21 INSERM - Institut National de la Santé et de la Recherche Médicale Hpv particles and uses thereof
WO2013119877A1 (en) 2012-02-07 2013-08-15 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
MX385842B (es) 2013-09-18 2025-03-18 Aura Biosciences Inc Conjugados de partículas de tipo virus y uso de las mismas.
CN104531741B (zh) * 2014-08-22 2016-08-24 天津康希诺生物技术有限公司 增强hpv抗原表位肽免疫原性的方法及类病毒颗粒、颗粒制备方法与应用
CN105801704B (zh) 2014-12-31 2020-06-02 艾托金生物医药(苏州)有限公司 一种具有抗宫颈癌细胞活性的重组疫苗构建方法及应用
AU2016308286B2 (en) 2015-08-18 2022-04-07 Rakuten Medical, Inc. Phthalocyanine dye conjugates and their storage
CN119564879A (zh) 2015-08-18 2025-03-07 乐天医药生技股份有限公司 用于光免疫疗法的组合物、联用及相关方法
WO2017075440A1 (en) 2015-10-30 2017-05-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Targeted cancer therapy
WO2018187515A1 (en) * 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
IL269986B2 (en) 2017-04-12 2024-06-01 Aura Biosciences Inc Targeted combination therapy
KR102797824B1 (ko) 2017-06-23 2025-04-17 버이뮨 아이엔씨. 키메라 바이러스-유사 입자 및 면역 반응의 항원-특이적 재지향자로서의 이의 용도
SG11202106931PA (en) 2018-12-27 2021-07-29 Verimmune Llc Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors
WO2021161179A1 (en) * 2020-02-10 2021-08-19 University Of Cape Town Plant produced bovine papillomavirus virus-like particles and pseudovirions
IL302190A (en) 2020-10-19 2023-06-01 Verimmune Inc Virus-induced preparations and methods for redirecting immune responses in the use of said preparations for cancer treatment
KR102821363B1 (ko) 2023-02-06 2025-06-13 영산대학교산학협력단 드론에 장착된 라이다 센서를 기초로 하는 수심 측량 시스템

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RU2206608C2 (ru) * 1994-05-16 2003-06-20 Мерк Энд Ко., Инк. Папилломавирусные вакцины
CA2486450A1 (en) * 2002-05-17 2003-11-27 University Of Cape Town Chimaeric human papillomavirus 16 l1 virus-like particles and method for preparing the particles
WO2010118424A2 (en) * 2009-04-10 2010-10-14 The Johns Hopkins University Papillomavirus-like particles (vlp) as broad spectrum human papillomavirus (hpv) vaccines
WO2010149752A2 (en) * 2009-06-25 2010-12-29 Glaxosmithline Biologicals S.A. Novel compositions

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WO2003068163A2 (en) 2002-02-14 2003-08-21 Novavax, Inc. Optimization of gene sequences of chimeric virus-like particles for expression in insect cells
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RU2206608C2 (ru) * 1994-05-16 2003-06-20 Мерк Энд Ко., Инк. Папилломавирусные вакцины
US20020016372A1 (en) * 2000-07-31 2002-02-07 Allison Anthony Clifford Method for preventing and treating alzheimer's disease and brain damage associated with cardiov ascular disease and head injury
CA2486450A1 (en) * 2002-05-17 2003-11-27 University Of Cape Town Chimaeric human papillomavirus 16 l1 virus-like particles and method for preparing the particles
WO2010118424A2 (en) * 2009-04-10 2010-10-14 The Johns Hopkins University Papillomavirus-like particles (vlp) as broad spectrum human papillomavirus (hpv) vaccines
WO2010149752A2 (en) * 2009-06-25 2010-12-29 Glaxosmithline Biologicals S.A. Novel compositions

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KIRNBAUER R. et al. Efficient Self-Assembly of Human Papillomavirus Type 16 LI and L1-L2 into Virus-Like Particles. JOURNAL OF VIROLOGY. 1993. V.67. No.12. P. 6929-6936. *
SCHELLENBACHER C. et al. Chimeric L1-L2 Virus-Like Particles as Potential Broad-Spectrum Human Papillomavirus Vaccines. JOURNAL OF VIROLOGY. 2009. V.83. No.19. P. 10085-10095;. *
VARSANI A. et al. Chimeric Human Papillomavirus Type 16 (HPV-16) L1 Particles Presenting the Common Neutralizing Epitope for the L2 Minor Capsid Protein of HPV-6 and HPV-16. JOURNAL OF VIROLOGY. 2003. V.77. No.15. P. 8386-8393;. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2806424C2 (ru) * 2019-07-19 2023-10-31 Синоселлтех Лтд. Поливалентная иммуногенная композиция против папилломавируса человека
US12440549B2 (en) 2019-07-19 2025-10-14 Sinocelltech Ltd. Polyvalent immunogenicity composition for human papillomavirus

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IL232584B (en) 2018-10-31
IN2014DN03054A (https=) 2015-05-15
CA2850293A1 (en) 2013-06-06
AU2012345443B2 (en) 2017-10-26
BR112014012491A2 (pt) 2017-06-06
ZA201403557B (en) 2020-10-28
EP2785842A1 (en) 2014-10-08
RU2014126587A (ru) 2016-01-27
US9771397B2 (en) 2017-09-26
CN103890177A (zh) 2014-06-25
CA2850293C (en) 2019-10-08
CN103890177B (zh) 2016-03-09
MY184076A (en) 2021-03-17
KR20140098061A (ko) 2014-08-07
JP6228922B2 (ja) 2017-11-08
MX2014006520A (es) 2014-11-21
US20140377367A1 (en) 2014-12-25
AU2012345443A1 (en) 2014-04-17
WO2013080187A1 (en) 2013-06-06
SG11201401579UA (en) 2014-07-30
EP2785842A4 (en) 2015-11-25
HK1198703A1 (en) 2015-05-29
JP2015500229A (ja) 2015-01-05
NZ622595A (en) 2016-04-29
PH12014500466A1 (en) 2022-05-11
MX355352B (es) 2018-04-17
KR102013801B1 (ko) 2019-08-23
IL232584A0 (en) 2014-06-30

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