RU2635317C2 - Лечение с применением перепрограммированных зрелых и дифференцированных клеток - Google Patents
Лечение с применением перепрограммированных зрелых и дифференцированных клеток Download PDFInfo
- Publication number
- RU2635317C2 RU2635317C2 RU2012120713A RU2012120713A RU2635317C2 RU 2635317 C2 RU2635317 C2 RU 2635317C2 RU 2012120713 A RU2012120713 A RU 2012120713A RU 2012120713 A RU2012120713 A RU 2012120713A RU 2635317 C2 RU2635317 C2 RU 2635317C2
- Authority
- RU
- Russia
- Prior art keywords
- cells
- cell
- patient
- reprogrammed
- blood
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/GB2009/051396 WO2011048350A1 (en) | 2009-10-19 | 2009-10-19 | Treatment using reprogrammed mature adult cells |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2012120713A RU2012120713A (ru) | 2013-11-27 |
RU2635317C2 true RU2635317C2 (ru) | 2017-11-10 |
Family
ID=42199514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2012120713A RU2635317C2 (ru) | 2009-10-19 | 2009-10-19 | Лечение с применением перепрограммированных зрелых и дифференцированных клеток |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2490702A1 (es) |
JP (1) | JP6073135B2 (es) |
KR (1) | KR101766203B1 (es) |
CN (1) | CN102647989A (es) |
AU (1) | AU2009354350B2 (es) |
CA (1) | CA2781522A1 (es) |
CH (1) | CH704227B1 (es) |
CU (1) | CU24006B1 (es) |
IL (1) | IL218902A (es) |
MA (1) | MA33740B1 (es) |
MX (1) | MX2012004522A (es) |
RU (1) | RU2635317C2 (es) |
TN (1) | TN2012000157A1 (es) |
UA (1) | UA109265C2 (es) |
WO (1) | WO2011048350A1 (es) |
ZA (1) | ZA201202664B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20170296595A1 (en) * | 2014-09-18 | 2017-10-19 | North Carolina State University | Mammalian Lung Spheroids and Lung Spheroid Cells and Uses Thereof |
JP6113133B2 (ja) | 2014-11-06 | 2017-04-12 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
AU2016337525B2 (en) | 2015-10-16 | 2022-01-20 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for inhibition of lineage specific antigens |
CN107114355A (zh) * | 2016-08-01 | 2017-09-01 | 北京世纪劲得生物技术有限公司 | 一种脂肪细胞保护液及其制备方法 |
KR20190141657A (ko) * | 2017-02-28 | 2019-12-24 | 보르 바이오파마, 인크. | 계통 특이적 단백질의 억제를 위한 조성물 및 방법 |
CN109731012A (zh) * | 2017-10-30 | 2019-05-10 | 邹兆中 | 提高生物免疫治疗有效物质活性的方法 |
CN109706119B (zh) * | 2018-04-13 | 2020-11-27 | 诺未科技(北京)有限公司 | 扩增造血干细胞的培养体系、方法及其用途 |
KR20220036908A (ko) | 2018-08-28 | 2022-03-23 | 보르 바이오파마 인크. | 유전자 조작된 조혈 줄기 세포 및 그의 용도 |
KR20200025210A (ko) * | 2018-08-29 | 2020-03-10 | 주식회사 스템모어 | 모유두 세포의 배양용 조성물 및 이를 이용한 모유두 세포의 배양 방법 |
WO2021240204A1 (en) * | 2020-05-23 | 2021-12-02 | Pakravan Nafiseh | Sperm head for resolution of inflammation, tissue repair & regeneration, and restoration of tissue function: new approach of cell therapy |
CN114231481B (zh) * | 2021-12-21 | 2023-07-18 | 中国人民解放军总医院 | 一种重编程真皮成纤维细胞为内皮祖细胞的化学诱导方法 |
WO2023217125A1 (zh) * | 2022-05-10 | 2023-11-16 | 上海赛立维生物科技有限公司 | 前列腺前体样细胞、细胞制剂及其制备方法和应用 |
WO2024050517A1 (en) * | 2022-09-02 | 2024-03-07 | The University Of North Carolina At Chapel Hill | Methods of making and using anticancer reprogrammed b cells |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA42726C2 (uk) * | 1993-05-24 | 2001-11-15 | Імм'Юнекс Корпорейшн | Виділений поліпептид, здатний зв'язувати flt3, виділений полінуклеотид, який кодує поліпептид, здатний зв'язувати flt3 (варіанти),виділений полінуклеотид, здатний гібридизуватися з ним (варіанти), вектор експресії (варіанти), лінія клітин- хазяїв (варіанти), спосіб одержання поліпептиду, здатного зв'язувати flt3 (варіанти), фармацевтична композиція, спосіб проведення аутологічної трансплантації хворому, який отримує цитовідновлювальну терапію, середовище для розмноження гемопоетичних клітин, спосіб трансфекції екзогенного гена в недиференційовану "ранню" гемопоетичну клітину, спосіб переносу екзогенного гена ссавцю, спосіб стимуляції проліферації т-клітин у ссавця, спосіб стимуляції проліферації клітин еритроїдного направлення диференціювання в селезінці ссавця, спосіб лікування хворого, який має симптоми мієлодиспластичного синдрому, спосіб лікування хворого, який має симптоми анемії, спосіб лікування хворого, який має симптоми синдрому набутого імунодефіциту, спосіб відокремлення клітин, які мають рецептор flt3 на їх поверхні, від суміші клітин в суспензії, антитіло, імунореактивне з поліпептидом, здатним зв'язувати flt3 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
US7112440B2 (en) * | 1995-02-02 | 2006-09-26 | Ghazi Jaswinder Dhoot | Method of increasing the relative number of CD45 low cells in a cell population |
US9068164B1 (en) * | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
WO1996035224A1 (en) * | 1995-05-02 | 1996-11-07 | Philips Electronics N.V. | Colour cathode ray tube |
US20050037490A1 (en) * | 1999-10-29 | 2005-02-17 | Lawrence Rosenberg | Medium for preparing dedifferentiated cells |
TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
WO2006014642A1 (en) * | 2004-07-22 | 2006-02-09 | Five Prime Therapeutics, Inc. | Method of producing autologous embryonic stem cells |
WO2010115052A2 (en) * | 2009-04-03 | 2010-10-07 | The Mclean Hospital Corporation | Induced pluripotent stem cells |
-
2009
- 2009-10-19 AU AU2009354350A patent/AU2009354350B2/en not_active Ceased
- 2009-10-19 UA UAA201205968A patent/UA109265C2/uk unknown
- 2009-10-19 CA CA2781522A patent/CA2781522A1/en not_active Abandoned
- 2009-10-19 RU RU2012120713A patent/RU2635317C2/ru not_active IP Right Cessation
- 2009-10-19 EP EP09736651A patent/EP2490702A1/en not_active Withdrawn
- 2009-10-19 WO PCT/GB2009/051396 patent/WO2011048350A1/en active Application Filing
- 2009-10-19 KR KR1020127012911A patent/KR101766203B1/ko active IP Right Grant
- 2009-10-19 CN CN2009801630439A patent/CN102647989A/zh active Pending
- 2009-10-19 CH CH00524/12A patent/CH704227B1/fr not_active IP Right Cessation
- 2009-10-19 JP JP2012534757A patent/JP6073135B2/ja not_active Expired - Fee Related
- 2009-10-19 MX MX2012004522A patent/MX2012004522A/es unknown
-
2012
- 2012-03-28 IL IL218902A patent/IL218902A/en not_active IP Right Cessation
- 2012-04-04 TN TNP2012000157A patent/TN2012000157A1/en unknown
- 2012-04-12 ZA ZA2012/02664A patent/ZA201202664B/en unknown
- 2012-04-19 CU CU2012000063A patent/CU24006B1/es active IP Right Grant
- 2012-05-11 MA MA34857A patent/MA33740B1/fr unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA42726C2 (uk) * | 1993-05-24 | 2001-11-15 | Імм'Юнекс Корпорейшн | Виділений поліпептид, здатний зв'язувати flt3, виділений полінуклеотид, який кодує поліпептид, здатний зв'язувати flt3 (варіанти),виділений полінуклеотид, здатний гібридизуватися з ним (варіанти), вектор експресії (варіанти), лінія клітин- хазяїв (варіанти), спосіб одержання поліпептиду, здатного зв'язувати flt3 (варіанти), фармацевтична композиція, спосіб проведення аутологічної трансплантації хворому, який отримує цитовідновлювальну терапію, середовище для розмноження гемопоетичних клітин, спосіб трансфекції екзогенного гена в недиференційовану "ранню" гемопоетичну клітину, спосіб переносу екзогенного гена ссавцю, спосіб стимуляції проліферації т-клітин у ссавця, спосіб стимуляції проліферації клітин еритроїдного направлення диференціювання в селезінці ссавця, спосіб лікування хворого, який має симптоми мієлодиспластичного синдрому, спосіб лікування хворого, який має симптоми анемії, спосіб лікування хворого, який має симптоми синдрому набутого імунодефіциту, спосіб відокремлення клітин, які мають рецептор flt3 на їх поверхні, від суміші клітин в суспензії, антитіло, імунореактивне з поліпептидом, здатним зв'язувати flt3 |
Non-Patent Citations (4)
Title |
---|
ILHAM SALEH ABULJADAYEL, ET AL., Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia, Research Article The Scientific World JOURNAL, 2006, 6, PP. 1278-;1297. * |
LUIGI ANASTASIA, ET AL., Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle, Cell Death and Differentiation, 2006, 13, PP. 2042-2051. * |
LUIGI ANASTASIA, ET AL., Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle, Cell Death and Differentiation, 2006, 13, PP. 2042-2051. ILHAM SALEH ABULJADAYEL, ET AL., Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia, Research Article The Scientific World JOURNAL, 2006, 6, PP. 1278-;1297. * |
SAITO M., ET AL., Vitamin B(12) promotes Cx40 and HCN4 gene expression at an early stage of cardiomyocyte differentiation. Exp Anim. 2009, 58, PP. 57-60. * |
Also Published As
Publication number | Publication date |
---|---|
IL218902A (en) | 2017-06-29 |
IL218902A0 (en) | 2012-06-28 |
JP2013508343A (ja) | 2013-03-07 |
CA2781522A1 (en) | 2011-04-28 |
AU2009354350A1 (en) | 2012-04-19 |
CU20120063A7 (es) | 2012-10-15 |
WO2011048350A1 (en) | 2011-04-28 |
MX2012004522A (es) | 2012-05-08 |
RU2012120713A (ru) | 2013-11-27 |
KR101766203B1 (ko) | 2017-08-08 |
CN102647989A (zh) | 2012-08-22 |
CH704227B1 (fr) | 2015-05-15 |
CU24006B1 (es) | 2014-06-27 |
AU2009354350B2 (en) | 2015-09-03 |
ZA201202664B (en) | 2013-02-27 |
MA33740B1 (fr) | 2012-11-01 |
KR20120099686A (ko) | 2012-09-11 |
EP2490702A1 (en) | 2012-08-29 |
TN2012000157A1 (en) | 2013-12-12 |
JP6073135B2 (ja) | 2017-02-01 |
UA109265C2 (uk) | 2015-08-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2635317C2 (ru) | Лечение с применением перепрограммированных зрелых и дифференцированных клеток | |
Can et al. | Umbilical cord mesenchymal stromal cell transplantations: a systemic analysis of clinical trials | |
US20140234268A1 (en) | Treatment using reprogrammed mature adult cells | |
EP2390311B1 (en) | Modulation of stem and progenitor cell differentiation, assays, and uses thereof | |
CN107429232B (zh) | 免疫调节性提高的细胞及其使用和生产方法 | |
EP2324109B1 (en) | Expansion of haemopoietic precursors | |
US20080085555A1 (en) | Method For In Vitro Amplification Of Adult Stem Cells | |
JP5431146B2 (ja) | 免疫学的寛容および調節性前駆細胞 | |
CN108478599A (zh) | 间充质基质细胞及其相关用途 | |
JP2003535144A (ja) | 多能性造血幹細胞の流動を刺激するヒト成長ホルモン | |
KR101843952B1 (ko) | 지방조직-유래 기질혈관분획의 분리 방법 | |
US20170106021A1 (en) | Compositions enriched for hox11+ stem cells and methods of preparing the same | |
US20080206196A1 (en) | Differentiation of cord blood into neural like cells, and method to treat neurological condition patients | |
TW201114895A (en) | Treatment using reprogrammed mature adult cells | |
JP2017008049A (ja) | 再プログラム化成熟成体細胞を用いる治療 | |
GB2474492A (en) | Treatment of medical conditions using reprogrammed cells | |
WO2019158712A1 (en) | Allogeneic composition | |
JP7277582B2 (ja) | タンパク質キナーゼc活性化剤で処理された幹細胞またはその培養物を含む自己免疫疾患の予防または治療用薬学的組成物 | |
AU2012200787C1 (en) | Modulation of stem and progenitor cell differentiation, assays, and uses thereof | |
CN114901806A (zh) | 细胞群以及其取得方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20181020 |