RU2633505C2 - Фармацевтическая композиция для лечения и/или профилактики рака - Google Patents

Фармацевтическая композиция для лечения и/или профилактики рака Download PDF

Info

Publication number
RU2633505C2
RU2633505C2 RU2014138038A RU2014138038A RU2633505C2 RU 2633505 C2 RU2633505 C2 RU 2633505C2 RU 2014138038 A RU2014138038 A RU 2014138038A RU 2014138038 A RU2014138038 A RU 2014138038A RU 2633505 C2 RU2633505 C2 RU 2633505C2
Authority
RU
Russia
Prior art keywords
antibody
caprin
cancer
seq
antibodies
Prior art date
Application number
RU2014138038A
Other languages
English (en)
Russian (ru)
Other versions
RU2014138038A (ru
Inventor
Синити КОБАЯСИ
Фумиеси ОКАНО
Таканори САИТО
Original Assignee
Торэй Индастриз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Торэй Индастриз, Инк. filed Critical Торэй Индастриз, Инк.
Publication of RU2014138038A publication Critical patent/RU2014138038A/ru
Application granted granted Critical
Publication of RU2633505C2 publication Critical patent/RU2633505C2/ru

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2014138038A 2012-02-21 2013-02-21 Фармацевтическая композиция для лечения и/или профилактики рака RU2633505C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012035491 2012-02-21
JP2012-035491 2012-02-21
PCT/JP2013/054345 WO2013125640A1 (ja) 2012-02-21 2013-02-21 癌の治療及び／又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
RU2014138038A RU2014138038A (ru) 2016-04-10
RU2633505C2 true RU2633505C2 (ru) 2017-10-12

Family

ID=49005817

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014138038A RU2633505C2 (ru) 2012-02-21 2013-02-21 Фармацевтическая композиция для лечения и/или профилактики рака

Country Status (17)

Country Link
US (1) US9266958B2 (Direct)
EP (1) EP2824114B1 (Direct)
JP (1) JP6187258B2 (Direct)
KR (1) KR102009236B1 (Direct)
CN (1) CN104114583B (Direct)
AU (1) AU2013223147B2 (Direct)
BR (1) BR112014021103A2 (Direct)
CA (1) CA2865020C (Direct)
DK (1) DK2824114T3 (Direct)
ES (1) ES2739380T3 (Direct)
HU (1) HUE045461T2 (Direct)
IN (1) IN2014KN01716A (Direct)
MX (1) MX360211B (Direct)
PL (1) PL2824114T3 (Direct)
PT (1) PT2824114T (Direct)
RU (1) RU2633505C2 (Direct)
WO (1) WO2013125640A1 (Direct)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0911926A2 (pt) 2008-08-05 2020-08-18 Toray Industries, Inc composições farmacêuticas, anticorpos e usos de um anticorpo ou um fragmento do mesmo.
ES2471379T3 (es) 2008-08-05 2014-06-26 Toray Industries, Inc. Método para detectar el cáncer
ES2540858T3 (es) * 2010-02-04 2015-07-14 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención de cáncer
DK2740489T3 (en) * 2011-08-04 2017-01-16 Toray Industries Pharmaceutical composition for the treatment and / or prevention of pancreatic cancer
PT2741085T (pt) * 2011-08-04 2017-06-30 Toray Industries Método para a deteção de cancro prancreático
RU2631804C2 (ru) 2012-02-21 2017-09-26 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения или профилактики рака
US9416193B2 (en) * 2012-03-30 2016-08-16 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of liver cancer
AU2013241043B2 (en) 2012-03-30 2017-11-09 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of gall bladder cancer
CN104471403B (zh) 2012-07-19 2017-03-01 东丽株式会社 癌的检测方法
MX358772B (es) 2012-07-19 2018-09-04 Toray Industries Metodo para detectar cancer.
KR102255616B1 (ko) 2013-08-09 2021-05-25 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
CN109843327B (zh) 2016-07-07 2022-05-13 小利兰·斯坦福大学托管委员会 抗体佐剂缀合物
CA3041979A1 (en) 2016-10-28 2018-05-03 Toray Industries, Inc. Pharmaceutical composition for cancer treatment and/or prevention
KR20200136935A (ko) 2018-03-30 2020-12-08 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
CA3130794A1 (en) 2019-03-15 2020-09-24 Bolt Biotherapeutics, Inc. Immunoconjugates targeting her2
CN114585390A (zh) 2019-06-13 2022-06-03 博尔特生物治疗药物有限公司 氨基苯并氮呯化合物、免疫缀合物及其用途
CN114746404A (zh) 2019-09-30 2022-07-12 博尔特生物治疗药物有限公司 酰胺连接的氨基苯并氮杂䓬免疫缀合物及其用途
MX2022004875A (es) 2019-10-25 2022-06-17 Bolt Biotherapeutics Inc Inmunoconjugados de tienoazepina, inmunoconjugados y usos de estos.
US20230159635A1 (en) * 2020-03-12 2023-05-25 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
WO2021182570A1 (ja) 2020-03-12 2021-09-16 東レ株式会社 癌の治療及び／又は予防のための医薬品
JP7793985B2 (ja) 2020-03-12 2026-01-06 東レ株式会社 癌の治療及び／又は予防のための医薬品
CA3175137A1 (en) 2020-03-12 2021-09-16 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
WO2021182571A1 (ja) 2020-03-12 2021-09-16 東レ株式会社 癌の治療及び／又は予防のための医薬品
WO2021226440A1 (en) 2020-05-08 2021-11-11 Bolt Biotherapeutics, Inc. Elastase-substrate, peptide linker immunoconjugates, and uses thereof
CA3186059A1 (en) 2020-08-13 2022-02-17 Romas Kudirka Pyrazoloazepine immunoconjugates, and uses thereof
WO2022270524A1 (ja) 2021-06-23 2022-12-29 東レ株式会社 癌の治療及び／又は予防のための医薬品
WO2022270523A1 (ja) 2021-06-23 2022-12-29 東レ株式会社 癌の治療及び／又は予防のための医薬品
KR20240041917A (ko) 2021-07-27 2024-04-01 도레이 카부시키가이샤 암의 치료 및/또는 예방을 위한 의약품
US20250325663A1 (en) 2021-07-27 2025-10-23 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
US20250066502A1 (en) 2021-07-27 2025-02-27 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
JPWO2023033129A1 (Direct) 2021-09-03 2023-03-09
US20250000995A1 (en) 2021-10-29 2025-01-02 Bolt Biotherapeutics, Inc. Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof
WO2024005123A1 (ja) 2022-06-30 2024-01-04 東レ株式会社 癌の治療及び／又は予防用医薬組成物
CN119744176A (zh) 2022-08-24 2025-04-01 东丽株式会社 用于癌的治疗和/或预防的药品
WO2024043252A1 (ja) 2022-08-24 2024-02-29 東レ株式会社 癌の治療及び／又は予防のための医薬品
JPWO2024043257A1 (Direct) 2022-08-24 2024-02-29
CN119768184A (zh) 2022-08-30 2025-04-04 东丽株式会社 用于癌的治疗和/或预防的药品
WO2024048541A1 (ja) 2022-08-30 2024-03-07 東レ株式会社 癌の治療及び／又は予防のための医薬品
EP4640235A1 (en) 2022-12-23 2025-10-29 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
EP4665404A1 (en) 2023-02-14 2025-12-24 Bolt Biotherapeutics, Inc. Aza-benzazepine immunoconjugates, and uses thereof
WO2024186626A1 (en) 2023-03-03 2024-09-12 Bolt Biotherapeutics, Inc. Aza-bicyclic sting agonist immunoconjugates, and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010016526A1 (ja) * 2008-08-05 2010-02-11 東レ株式会社 癌の治療及び予防用医薬組成物
WO2010016527A1 (ja) * 2008-08-05 2010-02-11 東レ株式会社 癌の検出方法
RU2418587C1 (ru) * 2010-01-21 2011-05-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО "НижГМА Росздрава") Способ лечения злокачественных опухолей головного мозга

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
ATE340590T1 (de) 1994-07-13 2006-10-15 Chugai Pharmaceutical Co Ltd Gegen menschliches interleukin-8 gerichteter, rekonstituierter menschlicher antikörper
US5698396A (en) 1995-06-07 1997-12-16 Ludwig Institute For Cancer Research Method for identifying auto-immunoreactive substances from a subject
FR2761994B1 (fr) 1997-04-11 1999-06-18 Centre Nat Rech Scient Preparation de recepteurs membranaires a partir de baculovirus extracellulaires
EP2363484A3 (en) 1998-04-03 2012-04-25 Chugai Seiyaku Kabushiki Kaisha Humanized antibody against human tissue factor (TF) and process of production of the humanized antibody
US20030118599A1 (en) 1999-04-02 2003-06-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
PL200772B1 (pl) 1998-07-14 2009-02-27 Corixa Corp Izolowany polipeptyd, fuzja białkowa oraz ich zastosowanie, izolowany epitop komórki T, wektor ekspresyjny, komórka gospodarza, sposób stymulowania i/lub namnażania komórek T, izolowana populacja komórek T, kompozycja i jej zastosowanie oraz izolowane komórki T
RU2234942C2 (ru) 1998-07-14 2004-08-27 Корикса Корпорейшн Выделенный опухолевый полипептид предстательной железы и кодирующий его полинуклеотид
US6969518B2 (en) 1998-12-28 2005-11-29 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6335170B1 (en) 1999-02-22 2002-01-01 Torben F. Orntoft Gene expression in bladder tumors
US6444425B1 (en) 1999-04-02 2002-09-03 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
HK1045332A1 (zh) 1999-04-02 2002-11-22 Corixa Corporation 用於治療和診斷肺癌的化合物及其使用方法
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
JP2003528587A (ja) 1999-10-29 2003-09-30 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ２７個のヒト分泌タンパク質
US20020006404A1 (en) 1999-11-08 2002-01-17 Idec Pharmaceuticals Corporation Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
HUP0500345A2 (hu) 2000-03-29 2005-07-28 Corixa Corporation Készítmények és alkalmazások tüdőrák kezelésére és diagnosztizálására
AU2002239422B2 (en) 2000-11-30 2006-12-07 E. R. Squibb & Sons, L.L.C. Transgenic transchromosomal rodents for making human antibodies
US7919467B2 (en) 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US20040029114A1 (en) 2001-01-24 2004-02-12 Eos Technology, Inc. Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
RU2306952C2 (ru) 2001-01-31 2007-09-27 Байоджен Айдек Инк. Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами
AU2002311787A1 (en) 2001-03-28 2002-10-15 Zycos Inc. Translational profiling
WO2002083070A2 (en) 2001-04-10 2002-10-24 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
AU2002311909A1 (en) 2001-05-11 2002-11-25 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
EP1970448A1 (en) 2001-05-11 2008-09-17 Kirin Pharma Kabushiki Kaisha Human artificial chromosome containting human antibody lambda light chain and non-human animal containting the human artificial chromosome capable of genetic transmission
US20030190640A1 (en) 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
JP2005535290A (ja) 2002-02-22 2005-11-24 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための組成物と方法
US20050003390A1 (en) 2002-05-17 2005-01-06 Axenovich Sergey A. Targets for controlling cellular growth and for diagnostic methods
WO2004007668A2 (en) 2002-07-12 2004-01-22 The Regents Of The University Of California Improved transporters and their uses
US20040126379A1 (en) 2002-08-21 2004-07-01 Boehringer Ingelheim International Gmbh Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents
US20070048301A1 (en) 2002-11-26 2007-03-01 Bodary-Winter Sarah C Compositions and methods for the treatment of immune related diseases
WO2004097051A2 (en) 2003-04-29 2004-11-11 Wyeth Methods for diagnosing aml and mds differential gene expression
JP2007516693A (ja) 2003-06-09 2007-06-28 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン 癌の治療および診断のための組成物および方法
WO2005007830A2 (en) 2003-07-14 2005-01-27 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
US20050032113A1 (en) 2003-07-17 2005-02-10 Mitsubishi Pharma Corporation Membrane protein library for proteome analysis and method for preparing same
EP2361929A1 (en) 2004-01-26 2011-08-31 Debiovision Inc. Neoplasm-specific polypeptides and their use
PT1735348E (pt) 2004-03-19 2012-07-24 Imclone Llc Anticorpo anti-receptor do factor de crescimento humano
PE20060287A1 (es) 2004-03-30 2006-05-16 Glaxo Group Ltd INMUNOGLOBULINAS DE UNION SELECTIVA A hOSM
WO2005100998A2 (en) 2004-04-16 2005-10-27 Europroteome Ag Membrane markers for use in cancer diagnosis and therapy
WO2006002378A2 (en) 2004-06-23 2006-01-05 Avalon Pharmaceuticals Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods
NZ556095A (en) 2005-01-21 2010-01-29 Genentech Inc Fixed dosing of her antibodies
EP1849002A4 (en) 2005-02-18 2008-08-20 Childrens Medical Center Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin
JP5069214B2 (ja) 2005-03-11 2012-11-07 ヴァーミリオン インコーポレイテッド 卵巣癌及び子宮内膜癌のバイオマーカー：ヘプシジン
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
US8014957B2 (en) 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
EP1991701A4 (en) 2006-02-14 2010-03-17 Dana Farber Cancer Inst Inc COMPOSITIONS, KITS AND METHODS OF IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF CANCER
WO2008073162A2 (en) 2006-08-17 2008-06-19 Cell Signaling Technology, Inc. Lysine acetylation sites
US20080107668A1 (en) 2006-08-30 2008-05-08 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
WO2008031041A2 (en) 2006-09-07 2008-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
WO2008059252A2 (en) 2006-11-15 2008-05-22 Oxford Biomedica (Uk) Limited Methods and composition fro t cell receptors which recognize 5t4 antigen
JP5663834B2 (ja) 2008-03-14 2015-02-04 東ソー株式会社 遺伝子組換え抗体の製造方法
KR101751065B1 (ko) 2008-03-18 2017-06-26 제넨테크, 인크. 항-ｈｅｒ２ 항체-약물 접합체와 화학요법제의 병용물, 및 사용 방법
PT2837383T (pt) 2008-08-05 2017-03-17 Toray Industries Agente de indução de imunidade
EP2467401B1 (en) 2009-08-19 2017-01-18 Merck Patent GmbH Antibodies for the detection of integrin complexes in ffpe material
JP5746183B2 (ja) 2009-09-22 2015-07-08 プロビオゲン アーゲー 特定のグリカン構造を含有する分子を生成する方法
ES2583777T3 (es) 2010-02-04 2016-09-22 Toray Industries, Inc. Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer
EP2532366B1 (en) 2010-02-04 2016-09-07 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
DK2532365T3 (en) 2010-02-04 2016-08-15 Toray Industries PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR PREVENTION OF CANCER
US8709418B2 (en) 2010-02-04 2014-04-29 Toray Industries, Inc. Pharmaceutical composition for treating CAPRIN-1 expressing cancer
ES2540858T3 (es) 2010-02-04 2015-07-14 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención de cáncer
RU2624029C2 (ru) * 2010-02-04 2017-06-30 Торэй Индастриз, Инк. Лекарственный препарат для лечения и/или профилактики рака
KR101271964B1 (ko) 2010-07-08 2013-06-07 강원대학교산학협력단 담낭암 치료용 약제학적 조성물 및 이를 이용한 담낭암의 성장, 전이 억제 및 치료 방법
PL2598531T3 (pl) 2010-07-26 2021-08-30 Progastrine Et Cancers S.À R.L. Sposoby i kompozycje do terapii nowotworu wątroby
JP5565183B2 (ja) 2010-08-06 2014-08-06 宇部興産株式会社 フィルムの製造方法
DK2740489T3 (en) 2011-08-04 2017-01-16 Toray Industries Pharmaceutical composition for the treatment and / or prevention of pancreatic cancer
PT2741085T (pt) 2011-08-04 2017-06-30 Toray Industries Método para a deteção de cancro prancreático
PT2740796T (pt) * 2011-08-04 2017-07-26 Toray Industries Composição farmacêutica para o tratamento e/ou profilaxia de cancro
US9416193B2 (en) 2012-03-30 2016-08-16 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of liver cancer
AU2013241043B2 (en) 2012-03-30 2017-11-09 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of gall bladder cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010016526A1 (ja) * 2008-08-05 2010-02-11 東レ株式会社 癌の治療及び予防用医薬組成物
WO2010016527A1 (ja) * 2008-08-05 2010-02-11 東レ株式会社 癌の検出方法
RU2418587C1 (ru) * 2010-01-21 2011-05-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО "НижГМА Росздрава") Способ лечения злокачественных опухолей головного мозга

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SOLOMON S. et al., Distinct Structural Features of Caprin-1 Mediate Its Interaction with G3BP-1 and Its Induction of Phosphorylation of Eukaryotic Translation Initiation Factor 2α, Entry to Cytoplasmic Stress Granules, and Selective Interaction with a Subset of mRNAs, MOLECULAR AND CELLULAR BIOLOGY, 2007, Vol. 27, No. 6, p. 2324-2342. *

Also Published As

Publication number Publication date
WO2013125640A1 (ja) 2013-08-29
DK2824114T3 (da) 2019-07-29
BR112014021103A8 (pt) 2018-01-23
MX360211B (es) 2018-10-24
US9266958B2 (en) 2016-02-23
AU2013223147B2 (en) 2017-10-05
CN104114583B (zh) 2019-11-19
JP6187258B2 (ja) 2017-08-30
BR112014021103A2 (pt) 2019-10-15
PL2824114T3 (pl) 2019-11-29
AU2013223147A1 (en) 2014-09-11
EP2824114A4 (en) 2015-10-07
EP2824114B1 (en) 2019-05-22
KR102009236B1 (ko) 2019-08-09
IN2014KN01716A (Direct) 2015-10-23
EP2824114A1 (en) 2015-01-14
CN104114583A (zh) 2014-10-22
CA2865020C (en) 2021-01-26
HUE045461T2 (hu) 2019-12-30
PT2824114T (pt) 2019-08-05
MX2014009749A (es) 2014-11-14
JPWO2013125640A1 (ja) 2015-07-30
CA2865020A1 (en) 2013-08-29
RU2014138038A (ru) 2016-04-10
US20150017172A1 (en) 2015-01-15
KR20140130671A (ko) 2014-11-11
ES2739380T3 (es) 2020-01-30

Similar Documents

Publication Publication Date Title
RU2633505C2 (ru) Фармацевтическая композиция для лечения и/или профилактики рака
RU2631804C2 (ru) Фармацевтическая композиция для лечения или профилактики рака
RU2632645C2 (ru) Фармацевтическая композиция для лечения и/или профилактики рака
RU2639522C2 (ru) Фармацевтическая композиция для лечения и/или профилактики рака
RU2611197C2 (ru) Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
RU2595400C2 (ru) Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
RU2610428C2 (ru) Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли
RU2624049C2 (ru) Фармацевтическая композиция для лечения и профилактики злокачественной опухоли
RU2678138C2 (ru) Фармацевтическая композиция для лечения и/или профилактики рака
RU2641260C2 (ru) Фармацевтическая композиция для лечения и профилактики злокачественной опухоли
BR112014021101B1 (pt) Anticorpo, composição farmacêutica e uso de um anticorpo ou seu fragmento, ou de uma composição