RU2612789C2 - Способ детектирования и характеризации токсиногенного штамма clostridium difficile - Google Patents

Способ детектирования и характеризации токсиногенного штамма clostridium difficile Download PDF

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RU2612789C2
RU2612789C2 RU2011144853A RU2011144853A RU2612789C2 RU 2612789 C2 RU2612789 C2 RU 2612789C2 RU 2011144853 A RU2011144853 A RU 2011144853A RU 2011144853 A RU2011144853 A RU 2011144853A RU 2612789 C2 RU2612789 C2 RU 2612789C2
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ДЕН БОГААРД Патрик Т. К. ВАН
Астрид Е. ВИССЕР
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Конинклейке Филипс Электроникс Н.В.
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium

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  • Chemical & Material Sciences (AREA)
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  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
RU2011144853A 2009-04-04 2010-03-31 Способ детектирования и характеризации токсиногенного штамма clostridium difficile RU2612789C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09157547.2 2009-04-07
EP09157547 2009-04-07
PCT/IB2010/051396 WO2010116290A1 (en) 2009-04-07 2010-03-31 Method for the detection and characterization of a toxinogenic clostridium difficile strain

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RU2011144853A RU2011144853A (ru) 2013-05-20
RU2612789C2 true RU2612789C2 (ru) 2017-03-13

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US (2) US20120028819A1 (enExample)
EP (1) EP2419527B1 (enExample)
JP (1) JP5859424B2 (enExample)
KR (1) KR101798211B1 (enExample)
CN (1) CN102378817B (enExample)
BR (1) BRPI1006757A2 (enExample)
RU (1) RU2612789C2 (enExample)
WO (1) WO2010116290A1 (enExample)

Cited By (1)

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RU2841390C1 (ru) * 2024-11-27 2025-06-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный аграрный университет" (ФГБОУ ВО СПбГАУ) Способ оценки генов токсинов Clostridium perfringens и Clostridioides difficile в консервированных объемистых кормах для крупного рогатого скота

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EP2419527B1 (en) 2009-04-07 2013-06-26 Koninklijke Philips Electronics N.V. Method for the detection and characterization of a toxinogenic clostridium difficile strain
WO2012087135A1 (en) 2010-12-22 2012-06-28 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Genetic markers specific for clostridium difficile ribotypes 027 (nap01/b1; rt 027) and 078 (nap7/8; rt 078) and their use
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MX345557B (es) 2011-07-06 2017-02-02 Quest Diagnostics Invest Inc Amplificacion y deteccion directa de patogenos virales y bacteriales.
GB201207998D0 (en) * 2012-05-08 2012-06-20 Univ Cardiff A screening method for the detection of clostridium difficle
US9133527B2 (en) * 2012-05-11 2015-09-15 Techlab, Inc. Cell wall protein CwpV (CD0514) as a diagnostic marker for Clostridium difficile ribotype 027
KR101955329B1 (ko) 2012-06-08 2019-03-07 삼성전자주식회사 클로스트리디움 디피실리 균주 검출용 조성물과 키트 및 이를 이용한 검출 방법
CN102952886A (zh) * 2012-11-28 2013-03-06 中华人民共和国张家港出入境检验检疫局 艰难梭菌肠毒素a、b双重荧光定量pcr检测方法及检测用试剂盒
US20140274770A1 (en) 2013-03-13 2014-09-18 Quidel Corporation Pcr assays and reagents for molecular detection of infectious agents
TWI504751B (zh) * 2013-09-25 2015-10-21 Univ Nat Cheng Kung 檢測困難梭狀桿菌核醣分型027之序列、技術平台及其方法
FI126289B (en) * 2014-12-19 2016-09-15 Mobidiag Ltd Method for detecting the presence of a hypervirulent strain of Clostridium difficile
US20190211377A1 (en) * 2016-12-22 2019-07-11 Roche Molecular Systems, Inc. Cobra probes to detect a marker for epidemic ribotypes of clostridium difficile
EP3724354A1 (en) * 2017-12-15 2020-10-21 Gen-Probe Incorporated Compositions and methods for detecting toxigenic clostridium difficile
EP3822370A1 (en) 2019-11-15 2021-05-19 Curiosity Diagnostics Sp. z o.o. Method of determining the presence of a hyper-virulent clostridioides difficile strain of the b1/nap1/027 group in a sample
CN111705150B (zh) * 2020-08-19 2020-12-25 中南大学湘雅医院 用于检测艰难梭菌核糖体027型毒力调节基因tcdC的方法、引物和试剂盒

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2841390C1 (ru) * 2024-11-27 2025-06-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный аграрный университет" (ФГБОУ ВО СПбГАУ) Способ оценки генов токсинов Clostridium perfringens и Clostridioides difficile в консервированных объемистых кормах для крупного рогатого скота

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CN102378817A (zh) 2012-03-14
EP2419527A1 (en) 2012-02-22
US10876174B2 (en) 2020-12-29
KR20120005019A (ko) 2012-01-13
RU2011144853A (ru) 2013-05-20
EP2419527B1 (en) 2013-06-26
US20180237827A1 (en) 2018-08-23
JP5859424B2 (ja) 2016-02-10
JP2012528567A (ja) 2012-11-15
KR101798211B1 (ko) 2017-11-15
US20120028819A1 (en) 2012-02-02
CN102378817B (zh) 2015-09-30
BRPI1006757A2 (pt) 2020-03-10
WO2010116290A1 (en) 2010-10-14

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