RU2602296C2 - Лекарственная форма и применение диэтилстильбестрола для лечения рака предстательной железы или молочной железы - Google Patents

Лекарственная форма и применение диэтилстильбестрола для лечения рака предстательной железы или молочной железы Download PDF

Info

Publication number
RU2602296C2
RU2602296C2 RU2013144383/15A RU2013144383A RU2602296C2 RU 2602296 C2 RU2602296 C2 RU 2602296C2 RU 2013144383/15 A RU2013144383/15 A RU 2013144383/15A RU 2013144383 A RU2013144383 A RU 2013144383A RU 2602296 C2 RU2602296 C2 RU 2602296C2
Authority
RU
Russia
Prior art keywords
diethylstilbestrol
matrix
pharmaceutical composition
film
des
Prior art date
Application number
RU2013144383/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2013144383A (ru
Inventor
Диана Шу-Лиан ЧОУ
Роланд А. АКО
Дзе Пхил РИОО
Чун Квонг ЧУ
Чжэн ВАН
Original Assignee
НАЛ Фармасьютикал Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by НАЛ Фармасьютикал Груп Лимитед filed Critical НАЛ Фармасьютикал Груп Лимитед
Publication of RU2013144383A publication Critical patent/RU2013144383A/ru
Application granted granted Critical
Publication of RU2602296C2 publication Critical patent/RU2602296C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2013144383/15A 2011-03-03 2012-03-02 Лекарственная форма и применение диэтилстильбестрола для лечения рака предстательной железы или молочной железы RU2602296C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/040,143 2011-03-03
US13/040,143 US8900634B2 (en) 2008-11-03 2011-03-03 Diethylstilbestrol dosage form and methods of treatment using thereof
PCT/GB2012/050475 WO2012117257A1 (en) 2011-03-03 2012-03-02 Diethylstilbestrol dosage form and use for the treatment of prostate or breast cancer

Publications (2)

Publication Number Publication Date
RU2013144383A RU2013144383A (ru) 2015-04-10
RU2602296C2 true RU2602296C2 (ru) 2016-11-20

Family

ID=45841525

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2013144383/15A RU2602296C2 (ru) 2011-03-03 2012-03-02 Лекарственная форма и применение диэтилстильбестрола для лечения рака предстательной железы или молочной железы

Country Status (13)

Country Link
US (1) US8900634B2 (enExample)
EP (1) EP2680813B1 (enExample)
JP (2) JP6059153B2 (enExample)
KR (1) KR101865776B1 (enExample)
CN (1) CN103561720A (enExample)
AU (2) AU2012223023B2 (enExample)
BR (1) BR112013022438A2 (enExample)
CA (1) CA2827892C (enExample)
ES (1) ES2733282T3 (enExample)
RU (1) RU2602296C2 (enExample)
SG (1) SG192845A1 (enExample)
TW (1) TWI548426B (enExample)
WO (1) WO2012117257A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof
MX2015004759A (es) * 2012-10-15 2015-10-12 Chamaeleo Pharma Bvba Fosfestrol para uso en el tratamiento curativo o paliativo de cancer en mamiferos hembras.
EP2906206A1 (en) 2012-10-15 2015-08-19 CHAMAELEO Pharma Bvba Sulfestrol for treating cancer
CA2888161A1 (en) 2012-10-15 2014-04-24 Chamaeleo Pharma Bvba Fosfestrol for use in curative or palliative treatment of prostate cancer
SG11201610358XA (en) 2014-06-24 2017-01-27 Catherine Lee Fast acting orally disintegrating film
CN105997857A (zh) * 2016-06-29 2016-10-12 冯志清 一种用于治疗猪乳房炎的注射液
WO2018091473A1 (en) 2016-11-15 2018-05-24 Klaria Pharma Holding Ab Pharmaceutical formulation
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
KR101940401B1 (ko) * 2017-06-12 2019-01-21 경상대학교산학협력단 맛이 차폐된 구강붕해필름 및 이의 제조방법
WO2019028457A2 (en) * 2017-08-04 2019-02-07 University Of Houston System FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE
GB201808462D0 (en) 2018-05-23 2018-07-11 Klaria Pharma Holding Ab Pharmaceutical formulation
WO2020030991A1 (en) * 2018-08-09 2020-02-13 Nal Pharmaceutical Group Limited Dosage form for insertion into the mouth
CN113133983B (zh) * 2020-01-20 2023-12-12 鲁南制药集团股份有限公司 一种治疗前列腺癌的药物组合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089726A1 (en) * 2004-03-12 2005-09-29 Smithkline Beecham Plc Pharmaceutical formulations
WO2009029543A1 (en) * 2007-08-24 2009-03-05 Aegis Therapeutics, Llc Controlled release formulations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
KR100554924B1 (ko) 1998-05-18 2006-03-03 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴 정제
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20020015730A1 (en) * 2000-03-09 2002-02-07 Torsten Hoffmann Pharmaceutical formulations and method for making
US20030147936A1 (en) 2002-02-07 2003-08-07 Velayudhan Sahadevan Prostatic hormonal implants treatment of prostate cancer
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
WO2008045461A2 (en) * 2006-10-11 2008-04-17 Oregon Health & Science University Transdermal diethylstilbestrol for treating prostate cancer
AU2008237246B2 (en) * 2007-04-05 2014-06-05 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089726A1 (en) * 2004-03-12 2005-09-29 Smithkline Beecham Plc Pharmaceutical formulations
WO2009029543A1 (en) * 2007-08-24 2009-03-05 Aegis Therapeutics, Llc Controlled release formulations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth

Also Published As

Publication number Publication date
EP2680813A1 (en) 2014-01-08
JP6059153B2 (ja) 2017-01-11
BR112013022438A2 (pt) 2016-12-06
EP2680813B1 (en) 2019-05-08
CN103561720A (zh) 2014-02-05
SG192845A1 (en) 2013-09-30
TW201249484A (en) 2012-12-16
US20110189288A1 (en) 2011-08-04
AU2017203009A1 (en) 2017-05-25
RU2013144383A (ru) 2015-04-10
WO2012117257A8 (en) 2013-09-19
KR20140021587A (ko) 2014-02-20
ES2733282T3 (es) 2019-11-28
WO2012117257A1 (en) 2012-09-07
KR101865776B1 (ko) 2018-06-08
US8900634B2 (en) 2014-12-02
JP2017061465A (ja) 2017-03-30
TWI548426B (zh) 2016-09-11
JP2014506914A (ja) 2014-03-20
AU2012223023B2 (en) 2017-03-16
CA2827892C (en) 2019-12-03
AU2017203009B2 (en) 2018-07-19
AU2012223023A1 (en) 2013-09-19
CA2827892A1 (en) 2012-09-07

Similar Documents

Publication Publication Date Title
RU2602296C2 (ru) Лекарственная форма и применение диэтилстильбестрола для лечения рака предстательной железы или молочной железы
US20240122846A1 (en) Pharmaceutical composition comprising an androgen receptor inhibitor
JP5213446B2 (ja) ジクロフェナクを含む医薬組成物
JP2003055203A (ja) ユビキノン含有製剤
HUE035013T2 (en) Delayed release, oral dosage compositions that contain amorphous cddo-me
CN102159196B (zh) 治疗上消化道用的药用制剂
IL205352A (en) Pharmaceutical preparations containing carbysmate aqueous preparations
EP2903690B1 (en) Enalapril compositions
DK2838510T3 (en) Atomoxetine solution
EA006015B1 (ru) Содержащая циклезонид фармацевтическая композиция, предназначенная для нанесения на слизистую оболочку
EA005201B1 (ru) Содержащая циклезонид водная фармацевтическая композиция
JPH1171269A (ja) 経口液体医薬製剤
JP2000128805A (ja) 多価不飽和脂肪酸および高分子ゲルからなる経粘膜吸収促進剤及びそれを含有する薬剤
CN105169409A (zh) 普萘洛尔或其可药用盐与离子交换树脂的复合物及其混悬液
HK1192153A (en) Diethylstilbestrol dosage form and use for the treatment of prostate or breast cancer
US20250152525A1 (en) Compositions and methods for the treatment of testosterone deficiency in males
CN118252797A (zh) 一种布地奈德黏性口服溶液、制备方法及其应用
CN118304279A (zh) 一种骨化三醇自微乳口溶膜及其制备方法
CN1265595A (zh) 含维生素d和钙的药物组合物,其制备方法和治疗应用
BG111495A (bg) Прахообразенфармацевтиченсъставсъдържащметамизол

Legal Events

Date Code Title Description
HZ9A Changing address for correspondence with an applicant