JP6059153B2 - ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用 - Google Patents

ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用 Download PDF

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Publication number
JP6059153B2
JP6059153B2 JP2013555938A JP2013555938A JP6059153B2 JP 6059153 B2 JP6059153 B2 JP 6059153B2 JP 2013555938 A JP2013555938 A JP 2013555938A JP 2013555938 A JP2013555938 A JP 2013555938A JP 6059153 B2 JP6059153 B2 JP 6059153B2
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Prior art keywords
sucrose
film
fatty acid
matrix
diethylstilbestrol
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JP2013555938A
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Japanese (ja)
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JP2014506914A5 (enExample
JP2014506914A (ja
Inventor
フィル リョー ジェ
フィル リョー ジェ
チュン クウォン チュ
チュン クウォン チュ
ワン チェン
ワン チェン
シュ−リアン チョウ ダイアナ
シュ−リアン チョウ ダイアナ
エー．アコ ローランド
エー．アコ ローランド
Original Assignee
エヌエーエル ファーマシューティカル グループ リミティド
エヌエーエル ファーマシューティカル グループ リミティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013555938A 2011-03-03 2012-03-02 ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用 Expired - Fee Related JP6059153B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/040,143 2011-03-03
US13/040,143 US8900634B2 (en) 2008-11-03 2011-03-03 Diethylstilbestrol dosage form and methods of treatment using thereof
PCT/GB2012/050475 WO2012117257A1 (en) 2011-03-03 2012-03-02 Diethylstilbestrol dosage form and use for the treatment of prostate or breast cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016199070A Division JP2017061465A (ja) 2011-03-03 2016-10-07 ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用

Publications (3)

Publication Number Publication Date
JP2014506914A JP2014506914A (ja) 2014-03-20
JP2014506914A5 JP2014506914A5 (enExample) 2015-03-19
JP6059153B2 true JP6059153B2 (ja) 2017-01-11

Family

ID=45841525

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013555938A Expired - Fee Related JP6059153B2 (ja) 2011-03-03 2012-03-02 ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用
JP2016199070A Withdrawn JP2017061465A (ja) 2011-03-03 2016-10-07 ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016199070A Withdrawn JP2017061465A (ja) 2011-03-03 2016-10-07 ジエチルスチルベストロール製剤、及び、前立腺又は乳癌の治療におけるその使用

Country Status (13)

Country Link
US (1) US8900634B2 (enExample)
EP (1) EP2680813B1 (enExample)
JP (2) JP6059153B2 (enExample)
KR (1) KR101865776B1 (enExample)
CN (1) CN103561720A (enExample)
AU (2) AU2012223023B2 (enExample)
BR (1) BR112013022438A2 (enExample)
CA (1) CA2827892C (enExample)
ES (1) ES2733282T3 (enExample)
RU (1) RU2602296C2 (enExample)
SG (1) SG192845A1 (enExample)
TW (1) TWI548426B (enExample)
WO (1) WO2012117257A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof
MX2015004759A (es) * 2012-10-15 2015-10-12 Chamaeleo Pharma Bvba Fosfestrol para uso en el tratamiento curativo o paliativo de cancer en mamiferos hembras.
EP2906206A1 (en) 2012-10-15 2015-08-19 CHAMAELEO Pharma Bvba Sulfestrol for treating cancer
CA2888161A1 (en) 2012-10-15 2014-04-24 Chamaeleo Pharma Bvba Fosfestrol for use in curative or palliative treatment of prostate cancer
SG11201610358XA (en) 2014-06-24 2017-01-27 Catherine Lee Fast acting orally disintegrating film
CN105997857A (zh) * 2016-06-29 2016-10-12 冯志清 一种用于治疗猪乳房炎的注射液
WO2018091473A1 (en) 2016-11-15 2018-05-24 Klaria Pharma Holding Ab Pharmaceutical formulation
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
KR101940401B1 (ko) * 2017-06-12 2019-01-21 경상대학교산학협력단 맛이 차폐된 구강붕해필름 및 이의 제조방법
WO2019028457A2 (en) * 2017-08-04 2019-02-07 University Of Houston System FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE
GB201808462D0 (en) 2018-05-23 2018-07-11 Klaria Pharma Holding Ab Pharmaceutical formulation
WO2020030991A1 (en) * 2018-08-09 2020-02-13 Nal Pharmaceutical Group Limited Dosage form for insertion into the mouth
CN113133983B (zh) * 2020-01-20 2023-12-12 鲁南制药集团股份有限公司 一种治疗前列腺癌的药物组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
KR100554924B1 (ko) 1998-05-18 2006-03-03 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴 정제
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20020015730A1 (en) * 2000-03-09 2002-02-07 Torsten Hoffmann Pharmaceutical formulations and method for making
US20030147936A1 (en) 2002-02-07 2003-08-07 Velayudhan Sahadevan Prostatic hormonal implants treatment of prostate cancer
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
WO2008045461A2 (en) * 2006-10-11 2008-04-17 Oregon Health & Science University Transdermal diethylstilbestrol for treating prostate cancer
AU2008237246B2 (en) * 2007-04-05 2014-06-05 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
WO2009029543A1 (en) 2007-08-24 2009-03-05 Aegis Therapeutics, Llc Controlled release formulations
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth

Also Published As

Publication number Publication date
EP2680813A1 (en) 2014-01-08
BR112013022438A2 (pt) 2016-12-06
EP2680813B1 (en) 2019-05-08
CN103561720A (zh) 2014-02-05
SG192845A1 (en) 2013-09-30
RU2602296C2 (ru) 2016-11-20
TW201249484A (en) 2012-12-16
US20110189288A1 (en) 2011-08-04
AU2017203009A1 (en) 2017-05-25
RU2013144383A (ru) 2015-04-10
WO2012117257A8 (en) 2013-09-19
KR20140021587A (ko) 2014-02-20
ES2733282T3 (es) 2019-11-28
WO2012117257A1 (en) 2012-09-07
KR101865776B1 (ko) 2018-06-08
US8900634B2 (en) 2014-12-02
JP2017061465A (ja) 2017-03-30
TWI548426B (zh) 2016-09-11
JP2014506914A (ja) 2014-03-20
AU2012223023B2 (en) 2017-03-16
CA2827892C (en) 2019-12-03
AU2017203009B2 (en) 2018-07-19
AU2012223023A1 (en) 2013-09-19
CA2827892A1 (en) 2012-09-07

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