TWI548426B - 己烯雌酚之劑型及治療方法 - Google Patents

己烯雌酚之劑型及治療方法 Download PDF

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Publication number
TWI548426B
TWI548426B TW101106943A TW101106943A TWI548426B TW I548426 B TWI548426 B TW I548426B TW 101106943 A TW101106943 A TW 101106943A TW 101106943 A TW101106943 A TW 101106943A TW I548426 B TWI548426 B TW I548426B
Authority
TW
Taiwan
Prior art keywords
diethylstilbestrol
weight
pharmaceutical composition
pharmaceutically acceptable
sucrose
Prior art date
Application number
TW101106943A
Other languages
English (en)
Chinese (zh)
Other versions
TW201249484A (en
Inventor
鄒淑蓮（戴安娜）
羅倫 爾 雅柯
柳濟弼
朱振光
王諍
Original Assignee
安能泰製藥有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 安能泰製藥有限公司 filed Critical 安能泰製藥有限公司
Publication of TW201249484A publication Critical patent/TW201249484A/zh
Application granted granted Critical
Publication of TWI548426B publication Critical patent/TWI548426B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW101106943A 2011-03-03 2012-03-02 己烯雌酚之劑型及治療方法 TWI548426B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/040,143 US8900634B2 (en) 2008-11-03 2011-03-03 Diethylstilbestrol dosage form and methods of treatment using thereof

Publications (2)

Publication Number Publication Date
TW201249484A TW201249484A (en) 2012-12-16
TWI548426B true TWI548426B (zh) 2016-09-11

Family

ID=45841525

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101106943A TWI548426B (zh) 2011-03-03 2012-03-02 己烯雌酚之劑型及治療方法

Country Status (13)

Country Link
US (1) US8900634B2 (enExample)
EP (1) EP2680813B1 (enExample)
JP (2) JP6059153B2 (enExample)
KR (1) KR101865776B1 (enExample)
CN (1) CN103561720A (enExample)
AU (2) AU2012223023B2 (enExample)
BR (1) BR112013022438A2 (enExample)
CA (1) CA2827892C (enExample)
ES (1) ES2733282T3 (enExample)
RU (1) RU2602296C2 (enExample)
SG (1) SG192845A1 (enExample)
TW (1) TWI548426B (enExample)
WO (1) WO2012117257A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715715B2 (en) * 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof
MX2015004759A (es) * 2012-10-15 2015-10-12 Chamaeleo Pharma Bvba Fosfestrol para uso en el tratamiento curativo o paliativo de cancer en mamiferos hembras.
EP2906206A1 (en) 2012-10-15 2015-08-19 CHAMAELEO Pharma Bvba Sulfestrol for treating cancer
CA2888161A1 (en) 2012-10-15 2014-04-24 Chamaeleo Pharma Bvba Fosfestrol for use in curative or palliative treatment of prostate cancer
SG11201610358XA (en) 2014-06-24 2017-01-27 Catherine Lee Fast acting orally disintegrating film
CN105997857A (zh) * 2016-06-29 2016-10-12 冯志清 一种用于治疗猪乳房炎的注射液
WO2018091473A1 (en) 2016-11-15 2018-05-24 Klaria Pharma Holding Ab Pharmaceutical formulation
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
KR101940401B1 (ko) * 2017-06-12 2019-01-21 경상대학교산학협력단 맛이 차폐된 구강붕해필름 및 이의 제조방법
WO2019028457A2 (en) * 2017-08-04 2019-02-07 University Of Houston System FORMULATION OF NANOSUSPENSION OF DIETHYLSTILBESTROL INJECTABLE
GB201808462D0 (en) 2018-05-23 2018-07-11 Klaria Pharma Holding Ab Pharmaceutical formulation
WO2020030991A1 (en) * 2018-08-09 2020-02-13 Nal Pharmaceutical Group Limited Dosage form for insertion into the mouth
CN113133983B (zh) * 2020-01-20 2023-12-12 鲁南制药集团股份有限公司 一种治疗前列腺癌的药物组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009029543A1 (en) * 2007-08-24 2009-03-05 Aegis Therapeutics, Llc Controlled release formulations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
KR100554924B1 (ko) 1998-05-18 2006-03-03 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴 정제
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20020015730A1 (en) * 2000-03-09 2002-02-07 Torsten Hoffmann Pharmaceutical formulations and method for making
US20030147936A1 (en) 2002-02-07 2003-08-07 Velayudhan Sahadevan Prostatic hormonal implants treatment of prostate cancer
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
WO2008045461A2 (en) * 2006-10-11 2008-04-17 Oregon Health & Science University Transdermal diethylstilbestrol for treating prostate cancer
AU2008237246B2 (en) * 2007-04-05 2014-06-05 University Of Kansas Rapidly dissolving pharmaceutical compositions comprising pullulan
US8900634B2 (en) * 2008-11-03 2014-12-02 Nal Pharmaceuticals, Ltd. Diethylstilbestrol dosage form and methods of treatment using thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009029543A1 (en) * 2007-08-24 2009-03-05 Aegis Therapeutics, Llc Controlled release formulations
US20100112050A1 (en) * 2008-11-03 2010-05-06 Je Phil Ryoo Dosage Form For Insertion Into The Mouth

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.Excipients and Food Chem.,Vol.1,no.2,pages13-20,July 2010 *

Also Published As

Publication number Publication date
EP2680813A1 (en) 2014-01-08
JP6059153B2 (ja) 2017-01-11
BR112013022438A2 (pt) 2016-12-06
EP2680813B1 (en) 2019-05-08
CN103561720A (zh) 2014-02-05
SG192845A1 (en) 2013-09-30
RU2602296C2 (ru) 2016-11-20
TW201249484A (en) 2012-12-16
US20110189288A1 (en) 2011-08-04
AU2017203009A1 (en) 2017-05-25
RU2013144383A (ru) 2015-04-10
WO2012117257A8 (en) 2013-09-19
KR20140021587A (ko) 2014-02-20
ES2733282T3 (es) 2019-11-28
WO2012117257A1 (en) 2012-09-07
KR101865776B1 (ko) 2018-06-08
US8900634B2 (en) 2014-12-02
JP2017061465A (ja) 2017-03-30
JP2014506914A (ja) 2014-03-20
AU2012223023B2 (en) 2017-03-16
CA2827892C (en) 2019-12-03
AU2017203009B2 (en) 2018-07-19
AU2012223023A1 (en) 2013-09-19
CA2827892A1 (en) 2012-09-07

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MM4A Annulment or lapse of patent due to non-payment of fees