RU2600824C1 - Method of increasing of non-specific body resistance in newborn calves - Google Patents

Abstract

FIELD: veterinary science.

SUBSTANCE: invention refers to veterinary science and aims at increasing of non-specific body resistance in newborn calves. For calves within 21 days daily oral administrated infusion on the basis of collection of nettle leaves, plantain and starwort herb, taken in ratio 1:1:1. Thus 8 g of raw material insist at 200 ml of boiling water for 60 minutes, filtered, deposit is removed. Infusion is fed a rate at 5 ml/kg of weight.

EFFECT: method enables effectively increase non-specific body resistance in newborn calves.

1 cl, 3 tbl, 1 ex

Description

The invention relates to veterinary medicine, in particular to veterinary pharmacology, can be used to increase nonspecific resistance of the body of newborn calves, as well as for the prevention of diseases of non-infectious etiology and in the complex treatment of these diseases.

There is also a method of increasing nonspecific resistance of calves, including the drinking of whole milk or a substitute for whole milk of a standard formulation against the background of the introduction of arabinogalactans from Siberian larch in the amount of 10 g per 1 head per day for 30 days [RF Patent No. 2350098]. This technical solution was taken by us as a prototype.

There is a method of increasing nonspecific resistance in calves, including intramuscular injection of glycopene against the background of additional oral administration of a bioactive veterinary preparation, which is an alcohol tincture of plant materials from a mixture of equal amounts of grass and purple coneflowers, common harmonica grass, small-leaved linden and licorice root RF №2370274]

The objective of the present invention was to expand the arsenal of tools that increase the nonspecific resistance of the body of newborn calves, based on available domestic raw materials and increase the persistent pharmacological effect in the face of a reduced rate of phytocorrection.

The problem is solved by the introduction of the infusion based on the collection of nettle leaves, plantain and stellate grass.

The essence of the invention lies in the fact that in a method of increasing nonspecific resistance, including daily oral administration of a herbal medicine to calves, the animals are administered infusion for 21 days on the basis of a collection of nettle leaves, plantain and stellate grass taken in a ratio of 1: 1: 1 , based on 5 ml / kg of the mass obtained by insisting 8 g of raw material per 200 ml of boiling water.

The implementation of the method. Newborn calves are orally administered daily infusion of nettle leaves, plantain and stellate grass at the rate of 5 ml / kg weight for 21 days. On 21 ^th day of the experiment, serum.

Cooking infusion. The leaves of nettle, plantain, stellate grass are crushed, mixed at the rate of 1: 1: 1, poured with boiling water at the rate of 8 g per 200 ml of water, infused for 60 minutes, filtered, the precipitate is removed, the infusion is cooled.

The method made it possible to increase the nonspecific resistance of the body of newborn calves, based on a decrease in the content of radical products and lipid peroxides in the animal organism and an increase in antioxidant activity, while reducing the duration of the course of phytocorrection to 21 days in comparison with the prototype.

The content of lipid peroxidation products in the blood plasma of calves of the control and experimental groups was studied on the 21st day of the experiment (table 1).

As a result of the studies, the content of lipid hydroperoxides in the blood of experimental calves was significantly lower by 26% relative to the control, diene conjugates - by 21%, malondialdehyde - by 17%.

The use of the infusion based on the collection of nettle leaves, plantain and stellate grass contributed to a significant increase in AOS activity in the blood of experimental animals: the content of ceruloplasmin increased by 26% compared to the same indicator in the group of control calves, vitamin E level - by 43%, glucose activity 6-phosphate dehydrogenase - by 31%, catalase - by 24% (table 2).

Within 30 days from the start of the experiment, the incidence and safety were controlled in calves of the control and experimental groups. In the control group of calves, 4 cases of simple form of dyspepsia were recorded (Table 3), 3 out of 15 animals fell, the complete clinical recovery of sick animals, characterized by an improvement in general condition and appetite, a denser consistency of excreted fecal masses, occurred on the 5-6th day. In the group of animals treated with the infusion, 1 case of simple dyspepsia was registered, clinical recovery occurred on the 3rd day. Phytoprophylaxis made it possible to ensure 100% preservation of calves, which exceeded this indicator in the control.

Thus, it has been experimentally established that it is possible to increase the nonspecific resistance of the body of calves by introducing an infusion based on the collection of nettle leaves, plantain and stellate grass, based on a decrease in the content of peroxidation products and an increase in the activity of the main components of the antioxidant system in the blood of animals, which gives reason to recommend the proposed method for use for the prevention and reduction of morbidity in livestock farms.

In general, based on the obtained experimental results, the proposed method provides a reduction in the course of phytocorrection to 21 days in comparison with the prototype, exhibiting a persistent pharmacological (antioxidant) effect.

The technical result of using the invention is to reduce the duration of the course of phytocorrection, providing an increase in nonspecific resistance, up to 21 days in comparison with the prototype under the conditions of oral administration of infusion based on the collection of nettle leaves, plantain and stellate grass with antioxidant activity.

Claims (1)

A method of increasing the nonspecific resistance of the body of newborn calves, including daily oral administration of animal herbal medicine to animals, characterized in that the collection of nettle leaves, plantain and stellate herb is taken in a ratio of 1: 1: 1, insist 8 g of raw material per 200 ml of boiling water in for 60 minutes, filter, remove the precipitate and evaporate the infusion at the rate of 5 ml / kg weight for 21 days.