RU2566382C2 - Система управления недостаточным заполнением для биосенсора - Google Patents
Система управления недостаточным заполнением для биосенсора Download PDFInfo
- Publication number
- RU2566382C2 RU2566382C2 RU2012158102/28A RU2012158102A RU2566382C2 RU 2566382 C2 RU2566382 C2 RU 2566382C2 RU 2012158102/28 A RU2012158102/28 A RU 2012158102/28A RU 2012158102 A RU2012158102 A RU 2012158102A RU 2566382 C2 RU2566382 C2 RU 2566382C2
- Authority
- RU
- Russia
- Prior art keywords
- sample
- compensation
- analyte
- initial
- control sensor
- Prior art date
Links
- 239000012491 analyte Substances 0.000 claims abstract description 176
- 238000004458 analytical method Methods 0.000 claims abstract description 114
- 238000001514 detection method Methods 0.000 claims abstract description 44
- 230000009897 systematic effect Effects 0.000 claims description 70
- 230000005284 excitation Effects 0.000 claims description 58
- 238000000034 method Methods 0.000 claims description 57
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 43
- 239000008103 glucose Substances 0.000 claims description 43
- 239000002131 composite material Substances 0.000 claims description 27
- 210000004369 blood Anatomy 0.000 claims description 24
- 239000008280 blood Substances 0.000 claims description 24
- 230000004044 response Effects 0.000 claims description 16
- 238000004891 communication Methods 0.000 claims description 11
- 210000003743 erythrocyte Anatomy 0.000 claims description 6
- 230000000670 limiting effect Effects 0.000 claims description 6
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 3
- 230000003247 decreasing effect Effects 0.000 claims description 2
- 230000011664 signaling Effects 0.000 claims description 2
- -1 red blood cells Substances 0.000 claims 3
- 238000005259 measurement Methods 0.000 abstract description 42
- 239000013060 biological fluid Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 239000000126 substance Substances 0.000 abstract description 7
- 230000007717 exclusion Effects 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 347
- 230000006870 function Effects 0.000 description 233
- 238000012360 testing method Methods 0.000 description 46
- 238000005534 hematocrit Methods 0.000 description 33
- 238000007726 management method Methods 0.000 description 33
- 239000002245 particle Substances 0.000 description 27
- 238000012544 monitoring process Methods 0.000 description 17
- 239000003153 chemical reaction reagent Substances 0.000 description 16
- 238000006479 redox reaction Methods 0.000 description 16
- 239000004020 conductor Substances 0.000 description 14
- 230000000875 corresponding effect Effects 0.000 description 12
- 230000006872 improvement Effects 0.000 description 11
- 230000002829 reductive effect Effects 0.000 description 11
- 230000008859 change Effects 0.000 description 10
- 238000004082 amperometric method Methods 0.000 description 6
- 230000007613 environmental effect Effects 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 238000003869 coulometry Methods 0.000 description 5
- 238000013500 data storage Methods 0.000 description 5
- 229940088598 enzyme Drugs 0.000 description 5
- 238000004832 voltammetry Methods 0.000 description 5
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 230000000295 complement effect Effects 0.000 description 4
- 238000012937 correction Methods 0.000 description 4
- 230000002427 irreversible effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000006722 reduction reaction Methods 0.000 description 4
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 229910002056 binary alloy Inorganic materials 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000001934 delay Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 230000027756 respiratory electron transport chain Effects 0.000 description 3
- 229940116269 uric acid Drugs 0.000 description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 235000021588 free fatty acids Nutrition 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000012067 mathematical method Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 238000004445 quantitative analysis Methods 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000003487 electrochemical reaction Methods 0.000 description 1
- 238000006056 electrooxidation reaction Methods 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000002977 intracellular fluid Anatomy 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 238000012886 linear function Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- DLZPPUIHGWXDNJ-UHFFFAOYSA-N n-phenylphenothiazin-3-imine Chemical class C1=CC=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 DLZPPUIHGWXDNJ-UHFFFAOYSA-N 0.000 description 1
- LJXXBBCNKKOAHS-UHFFFAOYSA-N n-phenylphenoxazin-3-imine Chemical class C1=CC=CC=C1N=C1C=C2OC3=CC=CC=C3N=C2C=C1 LJXXBBCNKKOAHS-UHFFFAOYSA-N 0.000 description 1
- 238000010606 normalization Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000004313 potentiometry Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 229910052707 ruthenium Inorganic materials 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
- G01N33/48771—Coding of information, e.g. calibration data, lot number
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35223410P | 2010-06-07 | 2010-06-07 | |
| US61/352,234 | 2010-06-07 | ||
| PCT/US2011/039382 WO2011156325A2 (en) | 2010-06-07 | 2011-06-07 | Underfill management system for a biosensor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2012158102A RU2012158102A (ru) | 2014-07-20 |
| RU2566382C2 true RU2566382C2 (ru) | 2015-10-27 |
Family
ID=44583361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012158102/28A RU2566382C2 (ru) | 2010-06-07 | 2011-06-07 | Система управления недостаточным заполнением для биосенсора |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9222910B2 (enExample) |
| EP (1) | EP2577303B1 (enExample) |
| JP (1) | JP5856155B2 (enExample) |
| KR (1) | KR101929058B1 (enExample) |
| CN (2) | CN103038636B (enExample) |
| BR (1) | BR112012031375A2 (enExample) |
| CA (2) | CA3047242A1 (enExample) |
| MX (2) | MX367439B (enExample) |
| RU (1) | RU2566382C2 (enExample) |
| WO (1) | WO2011156325A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2745479C1 (ru) * | 2017-07-03 | 2021-03-25 | Ф. Хоффманн-Ля Рош Аг | Способ и блок электроники для определения свойств биосенсора в условиях in vivo |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7232510B2 (en) * | 2000-11-30 | 2007-06-19 | Matsushita Electric Industrial Co., Ltd. | Biosensor, measuring instrument for biosensor, and method of quantifying substrate |
| US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
| JP5728568B2 (ja) * | 2011-02-23 | 2015-06-03 | パナソニックヘルスケアホールディングス株式会社 | 生体試料測定装置 |
| US8840776B2 (en) * | 2011-10-25 | 2014-09-23 | Bionime Corporation | Method and sensor strip for analysis of a sample |
| US9823214B2 (en) * | 2011-11-01 | 2017-11-21 | Panasonic Healthcare Holdings Co., Ltd. | Biological sample measuring apparatus |
| US9903830B2 (en) * | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
| US8877023B2 (en) * | 2012-06-21 | 2014-11-04 | Lifescan Scotland Limited | Electrochemical-based analytical test strip with intersecting sample-receiving chambers |
| US9005426B2 (en) * | 2012-09-28 | 2015-04-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| US9080196B2 (en) | 2012-09-28 | 2015-07-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| US8926369B2 (en) * | 2012-12-20 | 2015-01-06 | Lifescan Scotland Limited | Electrical connector for substrate having conductive tracks |
| TWI493186B (zh) * | 2013-02-08 | 2015-07-21 | Hmd Biomedical Inc | 檢測試片、檢測裝置及檢測方法 |
| US9157883B2 (en) | 2013-03-07 | 2015-10-13 | Lifescan Scotland Limited | Methods and systems to determine fill direction and fill error in analyte measurements |
| CN103412012B (zh) * | 2013-03-28 | 2015-09-09 | 利多(香港)有限公司 | 生物传感器 |
| US9435762B2 (en) * | 2013-06-27 | 2016-09-06 | Lifescan Scotland Limited | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
| WO2015004900A1 (ja) | 2013-07-08 | 2015-01-15 | パナソニックヘルスケア株式会社 | 血液成分の測定装置、血液成分の測定方法 |
| TWI576583B (zh) * | 2013-08-02 | 2017-04-01 | 達爾生技股份有限公司 | 生化檢測試片的判斷方法 |
| US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
| US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
| CN107076695B (zh) * | 2014-11-03 | 2020-01-17 | 豪夫迈·罗氏有限公司 | 用于电化学测试元件的电极布置及其使用方法 |
| CN104792832A (zh) * | 2015-04-16 | 2015-07-22 | 三诺生物传感股份有限公司 | 一种胆红素电化学传感器及其制备方法 |
| CN106226379A (zh) * | 2016-07-10 | 2016-12-14 | 浙江亿联健医疗器械有限公司 | 一种消除进样过程影响的生物传感器及测试方法 |
| CN109690304A (zh) | 2016-07-12 | 2019-04-26 | 安晟信医疗科技控股公司 | 通过使用来自两个电极的交替输出信号进行电化学分析的方法 |
| HUE052845T2 (hu) * | 2016-09-07 | 2021-05-28 | Hoffmann La Roche | Eljárások enzimalapú elektrokémiai érzékelõk tesztelésére |
| CN110249219B (zh) | 2016-12-05 | 2022-08-23 | 安晟信医疗科技控股公司 | 风险因素监测 |
| CN115644863A (zh) * | 2017-05-03 | 2023-01-31 | 雅培糖尿病护理公司 | 具有传感器数据的基于持续期的调整的系统、装置及方法 |
| EP4140396A1 (en) | 2017-11-21 | 2023-03-01 | MX3 Diagnostics, Inc. | Saliva testing system and method |
| US20210237058A1 (en) * | 2018-08-09 | 2021-08-05 | Hewlett-Packard Development Company, L.P. | Microfluidic devices to detect fluid priming |
| CN109884150B (zh) * | 2019-03-08 | 2021-05-14 | 武汉璟泓科技股份有限公司 | 一种红细胞积压校正方法及存储介质 |
| US11701036B2 (en) | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
| JP7699138B2 (ja) * | 2020-01-30 | 2025-06-26 | エムエックススリー・ダイアグノスティクス・インコーポレイテッド | 生体液試料の評価 |
| EP4218565A4 (en) * | 2020-09-28 | 2024-11-06 | Dong Woon Anatech Co. Ltd. | BIOSENSOR STRUCTURE FOR SAMPLE MEASUREMENT AND SAMPLE MEASUREMENT METHODS THEREFOR |
| JP7576528B2 (ja) * | 2021-09-16 | 2024-10-31 | アークレイ株式会社 | 測定方法及び測定装置 |
| CN115021836B (zh) * | 2022-05-31 | 2024-09-24 | 哲库科技(北京)有限公司 | 信号补偿方法及装置、频域补偿数据确定方法及装置 |
| CN115081949B (zh) * | 2022-07-28 | 2022-11-08 | 深圳赛桥生物创新技术有限公司 | 进样体积可调的样品工艺操作方法、装置、设备及介质 |
| CN119643645B (zh) * | 2025-02-18 | 2025-06-20 | 三诺生物传感股份有限公司 | 一种试条吸满判断方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2412204A1 (en) * | 2001-11-20 | 2003-05-20 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| US7132041B2 (en) * | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| US20090095071A1 (en) * | 2006-05-03 | 2009-04-16 | Bayer Healthcare Llc | Underfill Detection System For A Biosensor |
| US20090099787A1 (en) * | 2006-05-08 | 2009-04-16 | Bayer Healthcare Llc | Abnormal Output Detection System For A Biosensor |
| WO2009108239A2 (en) * | 2007-12-10 | 2009-09-03 | Bayer Healthcare Llc | Slope-based compensation |
| RU2008147646A (ru) * | 2006-05-03 | 2010-06-10 | БАЙЕР ХЕЛТКЭА ЭлЭлСи (US) | Система обнаружения состояния недостаточного заполнения для электрохимического биосенсора |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431004A (en) | 1981-10-27 | 1984-02-14 | Bessman Samuel P | Implantable glucose sensor |
| US5352351A (en) | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
| US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
| US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| DK0958495T3 (da) | 1997-02-06 | 2003-03-10 | Therasense Inc | In vitro analysand sensor med lille volumen |
| US6391645B1 (en) | 1997-05-12 | 2002-05-21 | Bayer Corporation | Method and apparatus for correcting ambient temperature effect in biosensors |
| HU222809B1 (hu) | 1997-10-03 | 2003-10-28 | 77 Elektronika Műszeripari Kft. | Eljárás és készülék kémiai összetevőnek anyagmintából, különösen vér glükóztartalmának vérmintából történő meghatározásához |
| ATE258028T1 (de) | 1998-05-13 | 2004-02-15 | Cygnus Therapeutic Systems | Signalverarbeitung zur messung von physiologischen analyten |
| US6576117B1 (en) | 1998-05-20 | 2003-06-10 | Arkray | Method and apparatus for electrochemical measurement using statistical technique |
| CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
| US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
| JP3972063B2 (ja) | 2001-01-17 | 2007-09-05 | アークレイ株式会社 | センサを用いる定量分析方法および定量分析装置 |
| US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
| US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
| AU784254B2 (en) | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
| US6797150B2 (en) | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| US7491310B2 (en) | 2001-10-12 | 2009-02-17 | Arkray, Inc. | Concentration measuring method and concentration measuring apparatus |
| CA2419213C (en) | 2002-03-07 | 2011-06-21 | Bayer Healthcare Llc | Improved electrical sensor |
| US6743635B2 (en) | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
| US6946299B2 (en) | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US6964871B2 (en) | 2002-04-25 | 2005-11-15 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| EP1541998B1 (en) | 2002-07-25 | 2011-05-18 | ARKRAY, Inc. | Sample analyzing method and sample analyzing device |
| EP1422523B1 (en) * | 2002-11-21 | 2007-05-23 | Lifescan, Inc. | Determination of sample volume adequacy in biosensors |
| US7488601B2 (en) | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
| US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| EP1714148B1 (en) | 2004-02-06 | 2011-11-02 | Bayer HealthCare LLC | Electrochemical biosensor |
| CN101006341A (zh) * | 2004-06-17 | 2007-07-25 | 拜尔健康护理有限责任公司 | 检测生物传感器的填充不足 |
| GB0501826D0 (en) | 2005-01-28 | 2005-03-09 | Melys Diagnostics Ltd | Apparatus for measurement of analyte concentration |
| WO2006109444A1 (ja) | 2005-03-22 | 2006-10-19 | Tomoaki Ito | 情報漏洩防護フィルム、携帯用小物入れ、カードケース及び情報漏洩防止板 |
| BRPI0609633B1 (pt) | 2005-04-08 | 2016-01-26 | Bayer Healthcare Llc | espécies oxidáveis como uma referência interna em soluções de controle para biossensores |
| CN110376270A (zh) * | 2005-07-20 | 2019-10-25 | 安晟信医疗科技控股公司 | 测定样品温度的方法 |
| ES2717135T3 (es) | 2005-07-20 | 2019-06-19 | Ascensia Diabetes Care Holdings Ag | Método para señalar al usuario para que añada una muestra adicional a una tira de prueba, método para medir la temperatura de una muestra y métodos para determinar la concentración de un analito basados en amperometría controlada |
| KR101477815B1 (ko) | 2005-09-30 | 2015-01-02 | 바이엘 헬스케어 엘엘씨 | 게이트형 전압 전류 측정법 |
| DE202005020335U1 (de) | 2005-12-28 | 2006-05-11 | Health & Life Co., Ltd., Chung-Ho | Biosensor mit einem Mikrokanal zur gleichzeitigen Bestimmung von mehreren biochemischen Stoffen |
| CA3044828A1 (en) * | 2006-02-27 | 2007-09-07 | Ascensia Diabetes Care Holdings Ag | Temperature adjusted analyte determination for biosensor systems |
| US7771583B2 (en) * | 2006-10-18 | 2010-08-10 | Agamatrix, Inc. | Electrochemical determination of analytes |
| US20110029318A1 (en) | 2008-06-16 | 2011-02-03 | Anna Pucar Rimhagen | Global operator license prioritizing and distribution |
| RU2509304C2 (ru) | 2008-12-08 | 2014-03-10 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Биосенсорная система с корректировкой сигнала |
| CA2776332C (en) | 2009-11-10 | 2018-05-01 | Bayer Healthcare Llc | Underfill recognition system for a biosensor |
| BR112012023984A2 (pt) * | 2010-03-22 | 2016-08-02 | Bayer Healthcare Llc | compensação residual para um biossensor |
-
2011
- 2011-06-07 JP JP2013514282A patent/JP5856155B2/ja active Active
- 2011-06-07 KR KR1020137000325A patent/KR101929058B1/ko active Active
- 2011-06-07 US US13/154,650 patent/US9222910B2/en active Active
- 2011-06-07 EP EP11752665.7A patent/EP2577303B1/en active Active
- 2011-06-07 MX MX2016007498A patent/MX367439B/es unknown
- 2011-06-07 BR BR112012031375A patent/BR112012031375A2/pt not_active IP Right Cessation
- 2011-06-07 WO PCT/US2011/039382 patent/WO2011156325A2/en not_active Ceased
- 2011-06-07 MX MX2012014281A patent/MX339815B/es active IP Right Grant
- 2011-06-07 CN CN201180028354.1A patent/CN103038636B/zh active Active
- 2011-06-07 RU RU2012158102/28A patent/RU2566382C2/ru active
- 2011-06-07 CA CA3047242A patent/CA3047242A1/en not_active Abandoned
- 2011-06-07 CA CA2798031A patent/CA2798031C/en not_active Expired - Fee Related
- 2011-06-07 CN CN201410799047.9A patent/CN104502426B/zh active Active
-
2015
- 2015-11-19 US US14/946,570 patent/US10175194B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2412204A1 (en) * | 2001-11-20 | 2003-05-20 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| US7132041B2 (en) * | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| US20090095071A1 (en) * | 2006-05-03 | 2009-04-16 | Bayer Healthcare Llc | Underfill Detection System For A Biosensor |
| RU2008147646A (ru) * | 2006-05-03 | 2010-06-10 | БАЙЕР ХЕЛТКЭА ЭлЭлСи (US) | Система обнаружения состояния недостаточного заполнения для электрохимического биосенсора |
| US20090099787A1 (en) * | 2006-05-08 | 2009-04-16 | Bayer Healthcare Llc | Abnormal Output Detection System For A Biosensor |
| WO2009108239A2 (en) * | 2007-12-10 | 2009-09-03 | Bayer Healthcare Llc | Slope-based compensation |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2745479C1 (ru) * | 2017-07-03 | 2021-03-25 | Ф. Хоффманн-Ля Рош Аг | Способ и блок электроники для определения свойств биосенсора в условиях in vivo |
| US11701037B2 (en) | 2017-07-03 | 2023-07-18 | Roche Diabetes Care, Inc. | Method and electronics unit for detecting in-vivo properties of a biosensor |
Also Published As
| Publication number | Publication date |
|---|---|
| US10175194B2 (en) | 2019-01-08 |
| US20110297557A1 (en) | 2011-12-08 |
| EP2577303A2 (en) | 2013-04-10 |
| CA3047242A1 (en) | 2011-12-15 |
| MX2012014281A (es) | 2013-01-24 |
| US20160077050A1 (en) | 2016-03-17 |
| MX339815B (es) | 2016-06-13 |
| JP5856155B2 (ja) | 2016-02-09 |
| CN103038636A (zh) | 2013-04-10 |
| WO2011156325A3 (en) | 2012-03-01 |
| EP2577303B1 (en) | 2022-08-03 |
| CN103038636B (zh) | 2015-01-14 |
| JP2013531792A (ja) | 2013-08-08 |
| CA2798031A1 (en) | 2011-12-15 |
| CN104502426A (zh) | 2015-04-08 |
| CA2798031C (en) | 2019-08-20 |
| HK1178253A1 (en) | 2013-09-06 |
| BR112012031375A2 (pt) | 2016-10-25 |
| HK1206813A1 (en) | 2016-01-15 |
| MX367439B (es) | 2019-08-22 |
| KR101929058B1 (ko) | 2018-12-13 |
| KR20130109087A (ko) | 2013-10-07 |
| CN104502426B (zh) | 2017-05-10 |
| US9222910B2 (en) | 2015-12-29 |
| WO2011156325A2 (en) | 2011-12-15 |
| RU2012158102A (ru) | 2014-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2566382C2 (ru) | Система управления недостаточным заполнением для биосенсора | |
| US10921278B2 (en) | Slope-based compensation including secondary output signals | |
| RU2509304C2 (ru) | Биосенсорная система с корректировкой сигнала | |
| CN101432620B (zh) | 用于电化学生物传感器的未足量检测系统 | |
| US9658187B2 (en) | Underfill recognition biosensor | |
| RU2568884C2 (ru) | Компенсация невязки для биодатчика | |
| JP2013528289A5 (enExample) | ||
| HK1178253B (en) | Underfill management system for a biosensor | |
| HK1206813B (en) | Method for determining analyte concentration in a sample |