JP5856155B2 - バイオセンサのための充填不足管理システム - Google Patents
バイオセンサのための充填不足管理システム Download PDFInfo
- Publication number
- JP5856155B2 JP5856155B2 JP2013514282A JP2013514282A JP5856155B2 JP 5856155 B2 JP5856155 B2 JP 5856155B2 JP 2013514282 A JP2013514282 A JP 2013514282A JP 2013514282 A JP2013514282 A JP 2013514282A JP 5856155 B2 JP5856155 B2 JP 5856155B2
- Authority
- JP
- Japan
- Prior art keywords
- sample
- correction
- test sensor
- initial
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000012360 testing method Methods 0.000 claims description 312
- 238000012937 correction Methods 0.000 claims description 253
- 230000006870 function Effects 0.000 claims description 197
- 239000012491 analyte Substances 0.000 claims description 179
- 238000004458 analytical method Methods 0.000 claims description 173
- 238000000034 method Methods 0.000 claims description 73
- 230000005284 excitation Effects 0.000 claims description 69
- 238000012886 linear function Methods 0.000 claims description 67
- 238000005259 measurement Methods 0.000 claims description 53
- 230000004044 response Effects 0.000 claims description 49
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 47
- 239000008103 glucose Substances 0.000 claims description 47
- 238000001514 detection method Methods 0.000 claims description 39
- 239000002131 composite material Substances 0.000 claims description 32
- 210000004369 blood Anatomy 0.000 claims description 25
- 239000008280 blood Substances 0.000 claims description 25
- 238000004891 communication Methods 0.000 claims description 9
- 210000003743 erythrocyte Anatomy 0.000 claims description 7
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims description 4
- 230000003247 decreasing effect Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 description 320
- 238000007726 management method Methods 0.000 description 51
- 238000005534 hematocrit Methods 0.000 description 33
- 239000003153 chemical reaction reagent Substances 0.000 description 16
- 238000006479 redox reaction Methods 0.000 description 16
- 239000004020 conductor Substances 0.000 description 14
- 238000004082 amperometric method Methods 0.000 description 11
- 239000013060 biological fluid Substances 0.000 description 11
- 230000008859 change Effects 0.000 description 10
- 230000006872 improvement Effects 0.000 description 10
- 230000000875 corresponding effect Effects 0.000 description 9
- 238000012545 processing Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 238000004832 voltammetry Methods 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 5
- 238000004364 calculation method Methods 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 238000003869 coulometry Methods 0.000 description 5
- 229940088598 enzyme Drugs 0.000 description 5
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 description 5
- 238000012546 transfer Methods 0.000 description 5
- 230000009466 transformation Effects 0.000 description 5
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 4
- 230000007717 exclusion Effects 0.000 description 4
- 230000002427 irreversible effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 230000000704 physical effect Effects 0.000 description 4
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 3
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 238000006722 reduction reaction Methods 0.000 description 3
- 230000009897 systematic effect Effects 0.000 description 3
- 229940116269 uric acid Drugs 0.000 description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000006399 behavior Effects 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 229910002056 binary alloy Inorganic materials 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000003722 extracellular fluid Anatomy 0.000 description 2
- 235000021588 free fatty acids Nutrition 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 238000012067 mathematical method Methods 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000010606 normalization Methods 0.000 description 2
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 101800000089 Movement protein P3N-PIPO Proteins 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- -1 compound metal complex Chemical class 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000003487 electrochemical reaction Methods 0.000 description 1
- 238000006056 electrooxidation reaction Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 238000013101 initial test Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- DLZPPUIHGWXDNJ-UHFFFAOYSA-N n-phenylphenothiazin-3-imine Chemical compound C1=CC=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 DLZPPUIHGWXDNJ-UHFFFAOYSA-N 0.000 description 1
- LJXXBBCNKKOAHS-UHFFFAOYSA-N n-phenylphenoxazin-3-imine Chemical compound C1=CC=CC=C1N=C1C=C2OC3=CC=CC=C3N=C2C=C1 LJXXBBCNKKOAHS-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000004313 potentiometry Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229910052707 ruthenium Inorganic materials 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 150000003624 transition metals Chemical class 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
- G01N33/48771—Coding of information, e.g. calibration data, lot number
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35223410P | 2010-06-07 | 2010-06-07 | |
| US61/352,234 | 2010-06-07 | ||
| PCT/US2011/039382 WO2011156325A2 (en) | 2010-06-07 | 2011-06-07 | Underfill management system for a biosensor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531792A JP2013531792A (ja) | 2013-08-08 |
| JP2013531792A5 JP2013531792A5 (enExample) | 2015-07-23 |
| JP5856155B2 true JP5856155B2 (ja) | 2016-02-09 |
Family
ID=44583361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013514282A Active JP5856155B2 (ja) | 2010-06-07 | 2011-06-07 | バイオセンサのための充填不足管理システム |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9222910B2 (enExample) |
| EP (1) | EP2577303B1 (enExample) |
| JP (1) | JP5856155B2 (enExample) |
| KR (1) | KR101929058B1 (enExample) |
| CN (2) | CN104502426B (enExample) |
| BR (1) | BR112012031375A2 (enExample) |
| CA (2) | CA3047242A1 (enExample) |
| MX (2) | MX367439B (enExample) |
| RU (1) | RU2566382C2 (enExample) |
| WO (1) | WO2011156325A2 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2096437B1 (en) * | 2000-11-30 | 2014-11-19 | Panasonic Healthcare Co., Ltd. | Biosensor for quantifying substrate |
| US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
| WO2012114706A1 (ja) * | 2011-02-23 | 2012-08-30 | パナソニック株式会社 | 生体試料測定装置 |
| US8840776B2 (en) * | 2011-10-25 | 2014-09-23 | Bionime Corporation | Method and sensor strip for analysis of a sample |
| JP5749806B2 (ja) * | 2011-11-01 | 2015-07-15 | パナソニックヘルスケアホールディングス株式会社 | 生体試料測定装置 |
| US9903830B2 (en) | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
| US8877023B2 (en) * | 2012-06-21 | 2014-11-04 | Lifescan Scotland Limited | Electrochemical-based analytical test strip with intersecting sample-receiving chambers |
| US9005426B2 (en) * | 2012-09-28 | 2015-04-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| US9080196B2 (en) | 2012-09-28 | 2015-07-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| US8926369B2 (en) * | 2012-12-20 | 2015-01-06 | Lifescan Scotland Limited | Electrical connector for substrate having conductive tracks |
| TWI493186B (zh) * | 2013-02-08 | 2015-07-21 | Hmd Biomedical Inc | 檢測試片、檢測裝置及檢測方法 |
| US9157883B2 (en) | 2013-03-07 | 2015-10-13 | Lifescan Scotland Limited | Methods and systems to determine fill direction and fill error in analyte measurements |
| CN103412012B (zh) * | 2013-03-28 | 2015-09-09 | 利多(香港)有限公司 | 生物传感器 |
| US9435762B2 (en) * | 2013-06-27 | 2016-09-06 | Lifescan Scotland Limited | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte |
| US9738916B2 (en) | 2013-07-08 | 2017-08-22 | Panasonic Healthcare Holdings Co., Ltd. | Blood component measurement device and blood component measurement method |
| CN104345079A (zh) * | 2013-08-02 | 2015-02-11 | 达尔生技股份有限公司 | 判断方法 |
| US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
| US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
| EP3216076B1 (en) * | 2014-11-03 | 2024-03-06 | F. Hoffmann-La Roche AG | Method of using electrochemical test elements having multiple electrode arrangements |
| CN104792832A (zh) * | 2015-04-16 | 2015-07-22 | 三诺生物传感股份有限公司 | 一种胆红素电化学传感器及其制备方法 |
| CN106226379A (zh) * | 2016-07-10 | 2016-12-14 | 浙江亿联健医疗器械有限公司 | 一种消除进样过程影响的生物传感器及测试方法 |
| EP3485265B1 (en) | 2016-07-12 | 2025-03-12 | Ascensia Diabetes Care Holdings AG | Method for electrochemical analysis by use of alternating output signals from two electrodes |
| ES2856174T3 (es) * | 2016-09-07 | 2021-09-27 | Hoffmann La Roche | Procedimientos para someter a prueba sensores electroquímicos basados en enzimas |
| WO2018104835A1 (en) * | 2016-12-05 | 2018-06-14 | Ascensia Diabetes Care Holdings Ag | Risk factor monitoring |
| EP3618712A1 (en) * | 2017-05-03 | 2020-03-11 | Abbott Diabetes Care Inc. | Systems, devices, and methods with duration-based adjustment of sensor data |
| JP6876157B2 (ja) * | 2017-07-03 | 2021-05-26 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | バイオセンサの生体内特性を検出する方法および電子ユニット |
| EP3713477B1 (en) | 2017-11-21 | 2022-07-06 | MX3 Diagnostics, Inc. | Saliva testing system and method |
| WO2020032957A1 (en) * | 2018-08-09 | 2020-02-13 | Hewlett-Packard Development Company, L.P. | Microfluidic devices to detect fluid priming |
| CN109884150B (zh) * | 2019-03-08 | 2021-05-14 | 武汉璟泓科技股份有限公司 | 一种红细胞积压校正方法及存储介质 |
| US11701036B2 (en) | 2019-07-10 | 2023-07-18 | MX3 Diagnostics, Inc. | Saliva test strip and method |
| WO2021154846A1 (en) * | 2020-01-30 | 2021-08-05 | MX3 Diagnostics, Inc. | Biological fluid sample assessment |
| JP7752879B2 (ja) * | 2020-09-28 | 2025-10-14 | ドンウン アナテック カンパニー リミテッド | 検体測定のためのバイオセンサ構造およびこれを利用した検体測定方法 |
| JP7576528B2 (ja) * | 2021-09-16 | 2024-10-31 | アークレイ株式会社 | 測定方法及び測定装置 |
| CN115021836B (zh) * | 2022-05-31 | 2024-09-24 | 哲库科技(北京)有限公司 | 信号补偿方法及装置、频域补偿数据确定方法及装置 |
| CN115081949B (zh) * | 2022-07-28 | 2022-11-08 | 深圳赛桥生物创新技术有限公司 | 进样体积可调的样品工艺操作方法、装置、设备及介质 |
| CN119643645B (zh) * | 2025-02-18 | 2025-06-20 | 三诺生物传感股份有限公司 | 一种试条吸满判断方法 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431004A (en) | 1981-10-27 | 1984-02-14 | Bessman Samuel P | Implantable glucose sensor |
| US5352351A (en) | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
| US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
| US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
| US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
| ATE227844T1 (de) | 1997-02-06 | 2002-11-15 | Therasense Inc | Kleinvolumiger sensor zur in-vitro bestimmung |
| US6391645B1 (en) | 1997-05-12 | 2002-05-21 | Bayer Corporation | Method and apparatus for correcting ambient temperature effect in biosensors |
| HU222809B1 (hu) | 1997-10-03 | 2003-10-28 | 77 Elektronika Műszeripari Kft. | Eljárás és készülék kémiai összetevőnek anyagmintából, különösen vér glükóztartalmának vérmintából történő meghatározásához |
| CA2311487C (en) | 1998-05-13 | 2004-02-10 | Cygnus, Inc. | Signal processing for measurement of physiological analytes |
| JP4256588B2 (ja) | 1998-05-20 | 2009-04-22 | アークレイ株式会社 | 統計的手法を用いた電気化学的測定方法および測定装置 |
| CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
| US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
| US7351323B2 (en) | 2001-01-17 | 2008-04-01 | Arkray, Inc. | Quantitative analyzing method and quantitative analyzer using sensor |
| US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
| US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
| AU784254B2 (en) | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
| US6797150B2 (en) | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| WO2003034055A1 (en) | 2001-10-12 | 2003-04-24 | Arkray, Inc. | Concentration measuring method and concentration measuring device |
| US6872298B2 (en) * | 2001-11-20 | 2005-03-29 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
| CA2419213C (en) | 2002-03-07 | 2011-06-21 | Bayer Healthcare Llc | Improved electrical sensor |
| US6964871B2 (en) | 2002-04-25 | 2005-11-15 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US6946299B2 (en) | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
| US6743635B2 (en) * | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
| EP2149792B1 (en) | 2002-07-25 | 2017-01-25 | ARKRAY, Inc. | Sample analyzing method |
| DE60220288T2 (de) * | 2002-11-21 | 2008-01-17 | Lifescan, Inc., Milpitas | Bestimmung der Genauigkeit eines Probevolumens in Biosensoren |
| US7132041B2 (en) * | 2003-02-11 | 2006-11-07 | Bayer Healthcare Llc | Methods of determining the concentration of an analyte in a fluid test sample |
| US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| US7488601B2 (en) | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
| JP4814110B2 (ja) | 2004-02-06 | 2011-11-16 | バイエル・ヘルスケア・エルエルシー | 電気化学的バイオセンサ |
| BRPI0512170A (pt) * | 2004-06-17 | 2008-02-12 | Bayer Healthcare Llc | detectando preenchimento incompleto de biosensores |
| GB0501826D0 (en) | 2005-01-28 | 2005-03-09 | Melys Diagnostics Ltd | Apparatus for measurement of analyte concentration |
| US20090067150A1 (en) | 2005-03-22 | 2009-03-12 | Tomoaki Ito | Protection Film for Preventing Leakage of Information, Portable Pouch, Card Case, and Information-Leakage Preventing Plate |
| RU2453843C2 (ru) | 2005-04-08 | 2012-06-20 | Байер Хелткэр Ллк | Окисляемые виды соединений в качестве внутреннего стандарта в контрольных растворах для биосенсоров |
| CN106970135B (zh) * | 2005-07-20 | 2019-09-06 | 安晟信医疗科技控股公司 | 门控电流分析法 |
| BRPI0613592A2 (pt) | 2005-07-20 | 2011-01-18 | Bayer Healthcare Llc | amperometria conectada por porta |
| WO2007040913A1 (en) | 2005-09-30 | 2007-04-12 | Bayer Healthcare Llc | Gated voltammetry |
| DE202005020335U1 (de) | 2005-12-28 | 2006-05-11 | Health & Life Co., Ltd., Chung-Ho | Biosensor mit einem Mikrokanal zur gleichzeitigen Bestimmung von mehreren biochemischen Stoffen |
| ES2791724T3 (es) * | 2006-02-27 | 2020-11-05 | Ascensia Diabetes Care Holdings Ag | Medida de analito ajustada en temperatura para sistemas de biosensor |
| EP2016399B1 (en) * | 2006-05-03 | 2019-08-28 | Ascensia Diabetes Care Holdings AG | Method for determining underfill in an electrochemical biosensor and underfill detection system |
| US7966859B2 (en) | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
| RU2465812C2 (ru) * | 2006-05-08 | 2012-11-10 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Система детектирования аномального выходного сигнала для биосенсора |
| US7771583B2 (en) | 2006-10-18 | 2010-08-10 | Agamatrix, Inc. | Electrochemical determination of analytes |
| EP2223104B1 (en) | 2007-12-10 | 2018-08-29 | Ascensia Diabetes Care Holdings AG | Slope-based compensation |
| US20110029318A1 (en) | 2008-06-16 | 2011-02-03 | Anna Pucar Rimhagen | Global operator license prioritizing and distribution |
| WO2010077660A1 (en) | 2008-12-08 | 2010-07-08 | Bayer Healthcare Llc | Biosensor system with signal adjustment |
| BR112012009291A2 (pt) | 2009-11-10 | 2016-05-31 | Bayer Healthcare Llc | sistema de reconhecimento de subenchimento para um biossensor |
| MX2012010860A (es) * | 2010-03-22 | 2013-03-05 | Bayer Healthcare Llc | Compensacion residual para un biosensor. |
-
2011
- 2011-06-07 BR BR112012031375A patent/BR112012031375A2/pt not_active IP Right Cessation
- 2011-06-07 JP JP2013514282A patent/JP5856155B2/ja active Active
- 2011-06-07 MX MX2016007498A patent/MX367439B/es unknown
- 2011-06-07 KR KR1020137000325A patent/KR101929058B1/ko active Active
- 2011-06-07 CN CN201410799047.9A patent/CN104502426B/zh active Active
- 2011-06-07 WO PCT/US2011/039382 patent/WO2011156325A2/en not_active Ceased
- 2011-06-07 US US13/154,650 patent/US9222910B2/en active Active
- 2011-06-07 EP EP11752665.7A patent/EP2577303B1/en active Active
- 2011-06-07 MX MX2012014281A patent/MX339815B/es active IP Right Grant
- 2011-06-07 CA CA3047242A patent/CA3047242A1/en not_active Abandoned
- 2011-06-07 CN CN201180028354.1A patent/CN103038636B/zh active Active
- 2011-06-07 RU RU2012158102/28A patent/RU2566382C2/ru active
- 2011-06-07 CA CA2798031A patent/CA2798031C/en not_active Expired - Fee Related
-
2015
- 2015-11-19 US US14/946,570 patent/US10175194B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20110297557A1 (en) | 2011-12-08 |
| US20160077050A1 (en) | 2016-03-17 |
| CA2798031C (en) | 2019-08-20 |
| KR101929058B1 (ko) | 2018-12-13 |
| CN104502426A (zh) | 2015-04-08 |
| US9222910B2 (en) | 2015-12-29 |
| RU2012158102A (ru) | 2014-07-20 |
| RU2566382C2 (ru) | 2015-10-27 |
| BR112012031375A2 (pt) | 2016-10-25 |
| EP2577303B1 (en) | 2022-08-03 |
| CA2798031A1 (en) | 2011-12-15 |
| CA3047242A1 (en) | 2011-12-15 |
| US10175194B2 (en) | 2019-01-08 |
| KR20130109087A (ko) | 2013-10-07 |
| WO2011156325A2 (en) | 2011-12-15 |
| CN103038636A (zh) | 2013-04-10 |
| MX367439B (es) | 2019-08-22 |
| HK1206813A1 (en) | 2016-01-15 |
| EP2577303A2 (en) | 2013-04-10 |
| HK1178253A1 (en) | 2013-09-06 |
| CN103038636B (zh) | 2015-01-14 |
| MX339815B (es) | 2016-06-13 |
| MX2012014281A (es) | 2013-01-24 |
| CN104502426B (zh) | 2017-05-10 |
| JP2013531792A (ja) | 2013-08-08 |
| WO2011156325A3 (en) | 2012-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5856155B2 (ja) | バイオセンサのための充填不足管理システム | |
| JP5856154B2 (ja) | 二次出力シグナルを含む勾配に基づく補正 | |
| US9658187B2 (en) | Underfill recognition biosensor | |
| CN101432620B (zh) | 用于电化学生物传感器的未足量检测系统 | |
| JP5695218B2 (ja) | サンプリング時間オフセットが改善された電気化学的分析における静電容量検出 | |
| JP6096655B2 (ja) | バイオセンサのための残差補正 | |
| JP2013528289A5 (enExample) | ||
| HK1178253B (en) | Underfill management system for a biosensor | |
| HK1206813B (en) | Method for determining analyte concentration in a sample | |
| HK1241019B (zh) | 用於检测使用过且变乾的传感器的系统和方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20140527 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20150116 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150302 |
|
| A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20150602 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20151111 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20151210 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5856155 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |