RU2529797C2 - Раковый маркер и терапевтическая мишень - Google Patents

Раковый маркер и терапевтическая мишень Download PDF

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RU2529797C2
RU2529797C2 RU2010123921/15A RU2010123921A RU2529797C2 RU 2529797 C2 RU2529797 C2 RU 2529797C2 RU 2010123921/15 A RU2010123921/15 A RU 2010123921/15A RU 2010123921 A RU2010123921 A RU 2010123921A RU 2529797 C2 RU2529797 C2 RU 2529797C2
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tumor
ccr4
cells
cancer
solid tumor
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RU2010123921/15A
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Russian (ru)
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RU2010123921A (ru
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Фрэнсис БЭЛКВИЛЛ
Вайолет СЛЭТТЕНААР
Джулия УИЛСОН
Яохэ ВАН
Тициана СКЬОППА
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Кэнсер Рисёч Текнолоджи Лтд
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2010123921/15A 2007-09-18 2008-09-18 Раковый маркер и терапевтическая мишень RU2529797C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0718167.0 2007-09-18
GB0718167A GB0718167D0 (en) 2007-09-18 2007-09-18 Cancer marker and therapeutic target
PCT/GB2008/003160 WO2009037454A2 (en) 2007-09-18 2008-09-18 Cancer marker and therapeutic target

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2014128513A Division RU2014128513A (ru) 2007-09-18 2014-07-14 Раковый маркер и терапевтическая мишень

Publications (2)

Publication Number Publication Date
RU2010123921A RU2010123921A (ru) 2011-12-20
RU2529797C2 true RU2529797C2 (ru) 2014-09-27

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RU2010123921/15A RU2529797C2 (ru) 2007-09-18 2008-09-18 Раковый маркер и терапевтическая мишень
RU2014128513A RU2014128513A (ru) 2007-09-18 2014-07-14 Раковый маркер и терапевтическая мишень

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US (2) US9134293B2 (cg-RX-API-DMAC7.html)
EP (3) EP2535716B1 (cg-RX-API-DMAC7.html)
JP (2) JP5774309B2 (cg-RX-API-DMAC7.html)
AU (1) AU2008300413B2 (cg-RX-API-DMAC7.html)
CA (1) CA2699702C (cg-RX-API-DMAC7.html)
DK (3) DK2176664T3 (cg-RX-API-DMAC7.html)
ES (3) ES2612690T3 (cg-RX-API-DMAC7.html)
GB (1) GB0718167D0 (cg-RX-API-DMAC7.html)
PL (3) PL2176664T3 (cg-RX-API-DMAC7.html)
RU (2) RU2529797C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009037454A2 (cg-RX-API-DMAC7.html)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
US20180125970A1 (en) * 2015-04-17 2018-05-10 Morphotek, Inc. Methods for treating lung cancer
RU2740254C2 (ru) * 2014-10-01 2021-01-12 Сфинготек Гмбх ОПРЕДЕЛЕНИЕ hGH ДЛЯ ПРИМЕНЕНИЯ ДЛЯ ПРЕДУПРЕЖДЕНИЯ ТЯЖЕЛОГО НЕБЛАГОПРИЯТНОГО СЕРДЕЧНО-СОСУДИСТОГО ЯВЛЕНИЯ ИЛИ СЕРДЕЧНО-СОСУДИСТОГО ЗАБОЛЕВАНИЯ У ИНДИВИДУУМА

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US20210163607A1 (en) 2017-05-19 2021-06-03 Nippon Zenyaku Kogyo Co., Ltd. Method for suppressing regulatory t cell infiltration by ccr4 inhibition and method for treating canine neoplastic disease
EP3843734A4 (en) 2018-08-29 2022-05-25 ChemoCentryx, Inc. Combination therapy using c-c chemokine receptor 4 (ccr4) antagonists and one or more immune checkpoint inhibitors

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US20070149449A1 (en) * 2003-02-14 2007-06-28 Morris David W Therapeutic targets in cancer
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2740254C2 (ru) * 2014-10-01 2021-01-12 Сфинготек Гмбх ОПРЕДЕЛЕНИЕ hGH ДЛЯ ПРИМЕНЕНИЯ ДЛЯ ПРЕДУПРЕЖДЕНИЯ ТЯЖЕЛОГО НЕБЛАГОПРИЯТНОГО СЕРДЕЧНО-СОСУДИСТОГО ЯВЛЕНИЯ ИЛИ СЕРДЕЧНО-СОСУДИСТОГО ЗАБОЛЕВАНИЯ У ИНДИВИДУУМА
US20180125970A1 (en) * 2015-04-17 2018-05-10 Morphotek, Inc. Methods for treating lung cancer
RU2718780C2 (ru) * 2015-04-17 2020-04-14 Эйсай Инк. Способы лечения рака легкого
RU2718780C9 (ru) * 2015-04-17 2020-07-08 Эйсай Инк. Способы лечения рака легкого

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EP2533047B1 (en) 2016-05-11
EP2533047A1 (en) 2012-12-12
AU2008300413B2 (en) 2014-09-11
JP5774309B2 (ja) 2015-09-09
EP2535716B1 (en) 2016-11-02
WO2009037454A3 (en) 2009-05-07
CA2699702A1 (en) 2009-03-26
WO2009037454A2 (en) 2009-03-26
EP2176664B1 (en) 2013-11-06
US20160223572A1 (en) 2016-08-04
JP2015212703A (ja) 2015-11-26
DK2176664T3 (da) 2014-01-20
ES2443541T3 (es) 2014-02-19
PL2535716T3 (pl) 2017-06-30
DK2535716T3 (en) 2017-02-13
US20100278844A1 (en) 2010-11-04
DK2533047T3 (en) 2016-08-22
CA2699702C (en) 2018-03-06
PL2176664T3 (pl) 2014-04-30
JP6234967B2 (ja) 2017-11-22
ES2612690T3 (es) 2017-05-18
US9134293B2 (en) 2015-09-15
GB0718167D0 (en) 2007-10-31
AU2008300413A1 (en) 2009-03-26
US10261099B2 (en) 2019-04-16
RU2010123921A (ru) 2011-12-20
PL2533047T3 (pl) 2016-11-30
RU2014128513A (ru) 2016-02-10
EP2535716A2 (en) 2012-12-19
ES2588507T3 (es) 2016-11-03
JP2010539508A (ja) 2010-12-16
EP2176664A2 (en) 2010-04-21
EP2535716A3 (en) 2013-03-13

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