RU2523383C2 - Протеиновые биомаркеры для диагностики заболевания мягких тканей и в качестве терапевтических мишеней для вмешательства в гигиену полости рта - Google Patents
Протеиновые биомаркеры для диагностики заболевания мягких тканей и в качестве терапевтических мишеней для вмешательства в гигиену полости рта Download PDFInfo
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56955—Bacteria involved in periodontal diseases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
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- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2010/029674 WO2010115034A2 (en) | 2009-04-01 | 2010-04-01 | Protein biomarkers for soft tissue disease diagnosis and as therapeutic targets for oral care intervention |
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| TWI405565B (zh) * | 2009-04-01 | 2013-08-21 | Colgate Palmolive Co | 口腔用組成物之抗－骨質流失及抗－牙周附連喪失之功效 |
| US9949671B2 (en) | 2013-03-13 | 2018-04-24 | Orthoaccel Technologies, Inc. | Diagnostic mouthpieces |
| WO2018129043A1 (en) * | 2017-01-03 | 2018-07-12 | The Trustees Of The University Of Pennsylvania | Compositions and methods for predicting risk of preterm birth |
| JP7245174B2 (ja) * | 2017-05-24 | 2023-03-23 | コーニンクレッカ フィリップス エヌ ヴェ | 唾液のｈｇｆ及びｍｍｐ－８に基づく歯周炎の診断 |
| EP3631462A1 (en) * | 2017-05-24 | 2020-04-08 | Koninklijke Philips N.V. | Diagnostics of gingivitis based on salivary il-1beta and hgf |
| AU2018272914A1 (en) | 2017-05-24 | 2020-01-23 | Koninklijke Philips N.V. | Diagnostics of mild or advanced periodontitis based on salivary IL-1beta and MMP-9 |
| CN111226118A (zh) | 2017-10-27 | 2020-06-02 | 加利福尼亚大学董事会 | 用于牙龈炎的唾液细胞外rna生物标记物 |
| EP3477306A1 (en) * | 2017-10-30 | 2019-05-01 | Koninklijke Philips N.V. | Classification of periodontitis patients |
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| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US4358437A (en) | 1978-11-29 | 1982-11-09 | Beecham Group Limited | Compositions |
| US5288480A (en) | 1987-01-30 | 1994-02-22 | Colgate-Palmolive Co. | Antiplaque antibacterial oral composition |
| GB9117140D0 (en) | 1991-08-08 | 1991-09-25 | Unilever Plc | Treatment of periodontitis |
| DE4226043A1 (de) | 1992-08-06 | 1994-02-10 | Haarmann & Reimer Gmbh | Mittel mit physiologischem Kühleffekt und für diese Mittel geeignete wirksame Verbindungen |
| US5840302A (en) | 1993-11-10 | 1998-11-24 | Bristol-Myers Squibb Company | Treatment of bacterially-induced inflammatory diseases |
| US5578295A (en) | 1995-04-28 | 1996-11-26 | The Procter & Gamble Company | Oral care compositions comprising certain substituted diphenyl ethers |
| ES2162304T3 (es) | 1996-06-12 | 2001-12-16 | Cognis Deutschland Gmbh | Preparaciones cosmeticas y/o farmaceuticas. |
| FR2794457B1 (fr) | 1999-06-01 | 2001-08-10 | Oreal | Derives carbonates de retinol, procede de preparation et utilisations |
| EP2295968B1 (en) | 1999-12-03 | 2012-09-19 | Baxter International Inc. | Pyrogenicity test for use with automated immunoassay systems |
| GB0001704D0 (en) | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Protein |
| US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US20020009740A1 (en) | 2000-04-14 | 2002-01-24 | Rima Kaddurah-Daouk | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
| US6500409B1 (en) | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
| DE10059584A1 (de) | 2000-11-30 | 2002-06-06 | Beiersdorf Ag | Kosmetische oder dermatologische getränkte Tücher |
| US7005225B2 (en) | 2002-11-12 | 2006-02-28 | Samsung Electronics Company | Organosol including amphipathic copolymeric binder having crystalline material, and use of the organosol to make dry tones for electrographic applications |
| TW200509958A (en) | 2003-02-14 | 2005-03-16 | Combinatorx Inc | Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines |
| GB2401865A (en) | 2003-05-22 | 2004-11-24 | Givaudan Sa | Antibacterial and antifungal glycerol monocarbonates |
| US7202234B2 (en) | 2003-10-24 | 2007-04-10 | Eisai Co., Ltd. | Compounds and methods for treating Toll-like receptor 2-related diseases and conditions |
| EP1701978B1 (en) | 2003-12-03 | 2009-02-11 | Whitehead Institute For Biomedical Research | Use of soluble T-Cadherin for the treatment of metabolic disorders |
| FI20040572A0 (fi) * | 2004-04-23 | 2004-04-23 | Ctt Cancer Targeting Tech Oy | Matriisi-metalloproteinaasin aktiviteetin inhibiittorit |
| US20050271601A1 (en) * | 2004-06-02 | 2005-12-08 | Nebojsa Milanovich | Anti-staining antibacterial dentifrice |
| WO2006068133A1 (ja) * | 2004-12-21 | 2006-06-29 | National University Corporation NARA Institute of Science and Technology | Ｎｆａｔ２発現抑制方法 |
| US20060141421A1 (en) | 2004-12-28 | 2006-06-29 | Kimberly-Clark Worldwide, Inc. | System and method for detecting substances related to oral health |
| WO2006074450A2 (en) | 2005-01-07 | 2006-07-13 | President And Fellows Of Harvard College | Methods and compositions for detecting and modulating periodontal disorders and periodontal diseases |
| AU2007204730B2 (en) * | 2006-01-10 | 2011-11-17 | Colgate-Palmolive Company | Methods of modulating cell surface receptors to prevent or reduce inflammation |
| US20080161394A1 (en) | 2006-11-23 | 2008-07-03 | Jean-Yves Fouron | Cosmetic composition comprising at least one volatile carbonic acid ester |
| WO2008093072A2 (en) | 2007-01-29 | 2008-08-07 | Paul Webb | Topical composition against contact dermatitis due to water |
| EP2207546A1 (en) | 2007-10-09 | 2010-07-21 | Humco Holding Group, Inc. | Antifungal treatment of nails |
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| MY179250A (en) | 2020-11-02 |
| EP2414837B1 (en) | 2015-06-03 |
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| CN102549432B (zh) | 2015-03-25 |
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| RU2011144032A (ru) | 2013-05-10 |
| TW201102653A (en) | 2011-01-16 |
| SG173461A1 (en) | 2011-09-29 |
| CN102549432A (zh) | 2012-07-04 |
| CA2753718C (en) | 2015-06-23 |
| CA2753718A1 (en) | 2010-10-07 |
| CO6430490A2 (es) | 2012-04-30 |
| US20120028261A1 (en) | 2012-02-02 |
| ZA201106056B (en) | 2015-05-27 |
| JP5643288B2 (ja) | 2014-12-17 |
| WO2010115034A2 (en) | 2010-10-07 |
| EP2414837A2 (en) | 2012-02-08 |
| AR076041A1 (es) | 2011-05-11 |
| US8753820B2 (en) | 2014-06-17 |
| BRPI1013184A2 (pt) | 2016-04-12 |
| MX2011008439A (es) | 2011-09-06 |
| JP2012522994A (ja) | 2012-09-27 |
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