RU2503464C2 - Биогель - Google Patents

Биогель Download PDF

Info

Publication number
RU2503464C2
RU2503464C2 RU2009119257/15A RU2009119257A RU2503464C2 RU 2503464 C2 RU2503464 C2 RU 2503464C2 RU 2009119257/15 A RU2009119257/15 A RU 2009119257/15A RU 2009119257 A RU2009119257 A RU 2009119257A RU 2503464 C2 RU2503464 C2 RU 2503464C2
Authority
RU
Russia
Prior art keywords
fibrinogen
biogel
carrier
binding groups
carriers
Prior art date
Application number
RU2009119257/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2009119257A (ru
Inventor
Грэг ВОЛКЕР
Original Assignee
Гемостатикс Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гемостатикс Лимитед filed Critical Гемостатикс Лимитед
Publication of RU2009119257A publication Critical patent/RU2009119257A/ru
Application granted granted Critical
Publication of RU2503464C2 publication Critical patent/RU2503464C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Surgical Instruments (AREA)
RU2009119257/15A 2006-11-27 2007-11-27 Биогель RU2503464C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0623607.9A GB0623607D0 (en) 2006-11-27 2006-11-27 Tissue adhesive
GB0623607.9 2006-11-27
PCT/GB2007/004538 WO2008065388A2 (en) 2006-11-27 2007-11-27 Biogel

Publications (2)

Publication Number Publication Date
RU2009119257A RU2009119257A (ru) 2011-01-10
RU2503464C2 true RU2503464C2 (ru) 2014-01-10

Family

ID=37636565

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009119257/15A RU2503464C2 (ru) 2006-11-27 2007-11-27 Биогель

Country Status (13)

Country Link
US (2) US9339584B2 (OSRAM)
EP (2) EP2099505B1 (OSRAM)
JP (2) JP5801994B2 (OSRAM)
CN (1) CN101687061B (OSRAM)
AU (1) AU2007327100B2 (OSRAM)
CA (1) CA2669738C (OSRAM)
DK (1) DK2099505T3 (OSRAM)
ES (2) ES2896053T3 (OSRAM)
GB (1) GB0623607D0 (OSRAM)
IL (1) IL198699A (OSRAM)
PL (1) PL2099505T3 (OSRAM)
RU (1) RU2503464C2 (OSRAM)
WO (1) WO2008065388A2 (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8623336B2 (en) 2008-12-15 2014-01-07 Council Of Scientific & Industrial Research Transparent xyloglucan/chitosan gel and a process for the preparation thereof
AU2011260258B2 (en) * 2010-06-01 2015-07-09 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
GB201101740D0 (en) 2011-02-01 2011-03-16 Haemostatix Ltd Therapeutic agents with improved fibrinogen binding
GB201201751D0 (en) * 2012-02-01 2012-03-14 Haemostatix Ltd Haemostatic wound dressing
MX356867B (es) * 2012-12-07 2018-06-18 Baxter Healthcare Sa Espuma hemostatica.
IL230151A0 (en) * 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One-component fibrin glue containing a polymerization inhibitor
GB201400292D0 (en) 2014-01-08 2014-02-26 Haemostatix Ltd Peptide dendrimers and agents
IL231792A0 (en) 2014-03-27 2014-08-31 Omrix Biopharmaceuticals Ltd Device and method for the preparation and administration of one-component fibrin glue
EA028039B1 (ru) * 2014-09-05 2017-09-29 Частное Учреждение Лаборатория Биотехнологических Исследований "3Д Биопринтинг Солюшенс" Устройство и способы печати биологических тканей и органов
IL235751A0 (en) * 2014-11-18 2015-02-26 Omrix Biopharmaceuticals Ltd An addition to the spray dryer
GB201508024D0 (en) 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic compositions
GB201508014D0 (en) * 2015-05-11 2015-06-24 Haemostatix Ltd Haemostatic device
US10159720B2 (en) 2015-12-08 2018-12-25 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, preparation and uses thereof
IL242984A0 (en) 2015-12-08 2016-02-29 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, their preparation and how to use them
CN107432955B (zh) * 2016-09-14 2020-09-04 四川蓝光英诺生物科技股份有限公司 用于制备生物构建体的方法和试剂盒
BR112019006932A2 (pt) 2016-10-06 2019-07-02 Matoke Holdings Limited composições antimicrobianas
WO2018065789A1 (en) 2016-10-06 2018-04-12 Matoke Holdings Limited Antimicrobial compositions
JP7431172B2 (ja) 2018-04-23 2024-02-14 ダニスコ・ユーエス・インク ホスホリラーゼ酵素を用いたβ-1,3グリコシド結合を含むグルカンの合成
CN110448719B (zh) * 2019-06-28 2020-05-22 浙江大学 一种促进凝血的丝素-多肽电纺膜及其制备方法
US20230105440A1 (en) * 2021-10-06 2023-04-06 Medtronic, Inc. Anti-thrombogenic coating

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377572A (en) * 1979-02-15 1983-03-22 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Tissue adhesive
RU2096415C1 (ru) * 1991-09-30 1997-11-20 Дзе Дюпон Мерк Фармасьютикал Компани Циклические пептиды или их фармацевтически приемлемые соли, фармацевтическая композиция
WO1999025383A1 (en) * 1997-11-14 1999-05-27 Quadrant Healthcare (Uk) Limited Conjugates comprising two active agents
WO2001097872A1 (en) * 2000-06-22 2001-12-27 Austin Sam L Bioadhesive compositions and methods of preparation and use
WO2002058750A2 (en) * 2001-01-25 2002-08-01 Nycomed Pharma As A suspension comprising fibrinogen, thrombin and alcohol and a method of coating a carrier with the same
CN1544098A (zh) * 2003-11-12 2004-11-10 邹金生 高效神经生长因子生物胶及其制备和使用方法
WO2005035002A1 (en) * 2003-10-07 2005-04-21 Haemostatix Limited Fibrinogen targetting microparticles for promoting haemostasie
WO2005076827A2 (en) * 2004-02-04 2005-08-25 Universita' Degli Studi Di Pavia Fbsa compositions for use in promoting fibrinogen aggregation and potentiating fibrin polymerization

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3171072D1 (en) 1981-06-25 1985-07-25 Stroetmann M Serapharm Enriched plasma derivative for promoting wound sealing and wound covering
US5357042A (en) 1984-04-23 1994-10-18 The General Hospital Corporation Synthetic peptides capable of eliciting fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
US5635477A (en) 1991-09-30 1997-06-03 The Dupont Merck Pharmaceutical Company Cyclic compounds useful as inhibitors of platelet glycoprotein IIB/IIIA
IL103252A (en) 1991-09-30 1997-03-18 Du Pont Merck Pharma CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FI954556A0 (fi) 1993-03-29 1995-09-26 Du Pont Merck Pharma Syklisiä yhdisteitä, jotka ovat käyttökelpoisia verihiutaleen glykoproteiinin IIb/IIIa inhibiittoreina
WO1995029686A1 (en) 1994-05-02 1995-11-09 E.R. Squibb & Sons, Inc. Recombinant fibrin chains, fibrin and fibrin-homologs
AU717906B2 (en) * 1994-12-07 2000-04-06 American National Red Cross, The Supplemented and unsupplemented tissue sealants, methods of their production and use
HUT77369A (hu) 1994-12-16 1998-03-30 Andaris Limited Keresztkötéses mikrorészecskék és felhasználásuk gyógyászati célú hordozóként
JPH11507630A (ja) 1995-06-06 1999-07-06 ヘモスフィアー,インコーポレイテッド 治療および診断用途のためのタンパク質粒子
WO1997044015A1 (en) 1996-05-17 1997-11-27 Andaris Limited Microparticles and their use in wound therapy
ATE284714T1 (de) 1996-10-21 2005-01-15 Quadrant Drug Delivery Ltd Plättchen-ersatzmittel und geeignetes konjugations-herstellungsverfahren
DE19849589C1 (de) * 1998-10-27 2000-06-15 Glatt Process Technology Gmbh Fibrin-Gewebekleber-Formulierung und Verfahren zu dessen Herstellung
CA2473727A1 (en) * 2001-12-04 2003-06-12 Christopher J. Woolverton Storage-stable fibrin sealant
EP1329438B1 (en) * 2002-01-14 2009-04-08 "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK", afgekort "V.I.T.O." Method for producing metallic and ceramic products
AU2003226265A1 (en) * 2002-04-05 2003-10-27 Baxter Healthcare S.A. Storage stable liquid sealer protein complex
CA2482856A1 (en) 2002-04-15 2003-10-30 American National Red Cross Plasma protein-binding ligands
WO2004045494A2 (en) 2002-11-20 2004-06-03 Bar-Ilan University Biological glue based on thrombin-conjugated nanoparticles
KR101077805B1 (ko) 2003-05-08 2011-10-28 카네카 코포레이션 전혈 처리가 가능한 저밀도 리포 단백 및 피브리노겐의 흡착재, 및 흡착기
AU2004253463B2 (en) 2003-06-16 2010-12-09 Loma Linda University Medical Center Deployable multifunctional hemostatic agent
US7129210B2 (en) * 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7833978B2 (en) * 2004-02-20 2010-11-16 Emory University Thrombomodulin derivatives and conjugates
US20060034935A1 (en) 2004-07-22 2006-02-16 Pronovost Allan D Compositions and methods for treating excessive bleeding
CN102091347A (zh) 2004-10-20 2011-06-15 伊西康公司 可吸收的止血物
GB0516091D0 (en) * 2005-08-04 2005-09-14 Haemostatix Ltd Therapeutic agent

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377572A (en) * 1979-02-15 1983-03-22 Immuno Aktiengesellschaft Fur Chemisch-Medizinische Produkte Tissue adhesive
RU2096415C1 (ru) * 1991-09-30 1997-11-20 Дзе Дюпон Мерк Фармасьютикал Компани Циклические пептиды или их фармацевтически приемлемые соли, фармацевтическая композиция
WO1999025383A1 (en) * 1997-11-14 1999-05-27 Quadrant Healthcare (Uk) Limited Conjugates comprising two active agents
WO2001097872A1 (en) * 2000-06-22 2001-12-27 Austin Sam L Bioadhesive compositions and methods of preparation and use
NZ523425A (en) * 2000-06-22 2006-02-24 Spinal Restoration Inc Biological tissue adhesives comprising fibrin sealant consisiting of fibrinogen and thrombin and a therapeutic agent for use in at discrete site within the body
WO2002058750A2 (en) * 2001-01-25 2002-08-01 Nycomed Pharma As A suspension comprising fibrinogen, thrombin and alcohol and a method of coating a carrier with the same
WO2005035002A1 (en) * 2003-10-07 2005-04-21 Haemostatix Limited Fibrinogen targetting microparticles for promoting haemostasie
CN1544098A (zh) * 2003-11-12 2004-11-10 邹金生 高效神经生长因子生物胶及其制备和使用方法
WO2005076827A2 (en) * 2004-02-04 2005-08-25 Universita' Degli Studi Di Pavia Fbsa compositions for use in promoting fibrinogen aggregation and potentiating fibrin polymerization

Also Published As

Publication number Publication date
EP3095468B1 (en) 2021-08-11
IL198699A (en) 2014-12-31
DK2099505T3 (en) 2016-05-30
WO2008065388A2 (en) 2008-06-05
ES2896053T8 (es) 2022-03-03
US9339584B2 (en) 2016-05-17
AU2007327100A1 (en) 2008-06-05
JP2010510818A (ja) 2010-04-08
CN101687061A (zh) 2010-03-31
PL2099505T3 (pl) 2016-08-31
US20160287659A1 (en) 2016-10-06
US20100249044A1 (en) 2010-09-30
US9913876B2 (en) 2018-03-13
JP2013188550A (ja) 2013-09-26
EP2099505B1 (en) 2016-02-17
ES2896053T3 (es) 2022-02-23
CA2669738A1 (en) 2008-06-05
ES2570760T3 (es) 2016-05-20
CN101687061B (zh) 2013-03-27
HK1231419A1 (en) 2017-12-22
JP5801994B2 (ja) 2015-10-28
WO2008065388A3 (en) 2009-11-26
RU2009119257A (ru) 2011-01-10
EP3095468A1 (en) 2016-11-23
IL198699A0 (en) 2010-02-17
AU2007327100B2 (en) 2014-03-06
EP2099505A2 (en) 2009-09-16
CA2669738C (en) 2017-05-30
GB0623607D0 (en) 2007-01-03

Similar Documents

Publication Publication Date Title
JP5801994B2 (ja) バイオゲル
US9808553B2 (en) Haemostatic wound dressing
US9717820B2 (en) Procoagulant peptides and their derivatives and uses therefor
RU2719562C2 (ru) Пептидные дендримеры, содержащие фибриноген-связывающие пептиды
CN101267843A (zh) 人造血小板
HK1231419B (en) Biogel
KR20230113529A (ko) 지혈 제어를 개선하기 위한 시스템