RU2436590C1 - Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости - Google Patents

Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости Download PDF

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Publication number
RU2436590C1
RU2436590C1 RU2010126653/15A RU2010126653A RU2436590C1 RU 2436590 C1 RU2436590 C1 RU 2436590C1 RU 2010126653/15 A RU2010126653/15 A RU 2010126653/15A RU 2010126653 A RU2010126653 A RU 2010126653A RU 2436590 C1 RU2436590 C1 RU 2436590C1
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Russia
Prior art keywords
aat
cfs
alpha
antitrypsin
patients
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RU2010126653/15A
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English (en)
Russian (ru)
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КИНТАНА Ана ГАРСИЯ (ES)
КИНТАНА Ана ГАРСИЯ
МАРТИН Хосе АЛЕГРЕ (ES)
МАРТИН Хосе АЛЕГРЕ
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Грифольс, С.А.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4826Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/56Protease inhibitors from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
RU2010126653/15A 2009-06-30 2010-06-29 Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости RU2436590C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200930387 2009-06-30
ES200930387A ES2332645B1 (es) 2009-06-30 2009-06-30 Utilizacion de alfa-1-antitripsina para la preparacion de medicamentos para el tratamiento del sindrome de fatiga cronica.

Publications (1)

Publication Number Publication Date
RU2436590C1 true RU2436590C1 (ru) 2011-12-20

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RU2010126653/15A RU2436590C1 (ru) 2009-06-30 2010-06-29 Применение альфа-1-антитрипсина для получения лекарственных средств для лечения синдрома хронической усталости

Country Status (16)

Country Link
US (1) US9205134B2 (enExample)
EP (1) EP2289540B1 (enExample)
JP (1) JP5231490B2 (enExample)
CN (1) CN101934071B (enExample)
AR (1) AR077123A1 (enExample)
AU (1) AU2010202203B2 (enExample)
BR (1) BRPI1002087B1 (enExample)
CA (1) CA2706212C (enExample)
CL (1) CL2010000575A1 (enExample)
ES (2) ES2332645B1 (enExample)
MX (1) MX2010006125A (enExample)
NZ (1) NZ585890A (enExample)
PL (1) PL2289540T3 (enExample)
PT (1) PT2289540E (enExample)
RU (1) RU2436590C1 (enExample)
UY (1) UY32670A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2840475C2 (ru) * 2021-05-03 2025-05-26 Ажероникс Са Альфа-1-антитрипсин (ААТ) в лечении и (или) профилактике неврологических нарушений

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* Cited by examiner, † Cited by third party
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WO2013096458A1 (en) * 2011-12-19 2013-06-27 Gtc Biotherapeutics, Inc. Recombinant human alpha-1-antitrypsin for the treatment of inflammatory disorders
WO2014140927A2 (en) 2013-02-13 2014-09-18 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Proteins with modified glycosylation and methods of production thereof
US20220160847A1 (en) * 2020-11-20 2022-05-26 Mark Egly Method of preventing and/or treating a plurality of diseases
WO2023184473A1 (zh) * 2022-04-01 2023-10-05 首创生物技术有限公司 肽用于治疗神经退行性疾病或改善认知功能的用途

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WO1992020327A1 (en) * 1991-05-14 1992-11-26 Ernir Snorrason Treatment of fatigue syndrome with cholinesterase inhibitors
WO1998005350A1 (en) * 1996-08-08 1998-02-12 Milkhaus Laboratory, Inc. Materials and methods for treatment of plaquing diseases
WO2000051623A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
WO2008143633A2 (en) * 2007-01-10 2008-11-27 University Of Florida Compounds and methods for treatment of alpha-1 antitrypsin deficiency
US7459532B2 (en) * 2003-05-12 2008-12-02 Bristol-Myers Squibb Company Variants of the TRP channel family member, LTRPC3G

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US20040043510A1 (en) * 2000-07-14 2004-03-04 Nobuyuki Shigetoh Particle-labeled protein and immuno-chromatograph using the same
CA2506839A1 (en) 2002-11-20 2004-06-03 Arriva-Prometic Inc. Composition and method for treating inflammatory diseases using protease inhibitors
PL2520654T3 (pl) * 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
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ES2281222B1 (es) * 2004-09-24 2008-06-01 Grifols, S.A. Utilizacion de alfa-1 antitripsina para la preparacion de medicamentos para el tratamiento de la fibromialgia.
EP2203051A4 (en) * 2007-09-25 2011-09-07 Abbott Lab OCTAHYDROPENTAL COMPOUNDS AS CHEMOKIN RECEPTOR ANTAGONISTS
CA2703393C (en) 2007-11-02 2018-07-24 Talecris Biotherapeutics, Inc. Method, composition, and article of manufacture for providing alpha-1 antitrypsin

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WO1992020327A1 (en) * 1991-05-14 1992-11-26 Ernir Snorrason Treatment of fatigue syndrome with cholinesterase inhibitors
WO1998005350A1 (en) * 1996-08-08 1998-02-12 Milkhaus Laboratory, Inc. Materials and methods for treatment of plaquing diseases
WO2000051623A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US7459532B2 (en) * 2003-05-12 2008-12-02 Bristol-Myers Squibb Company Variants of the TRP channel family member, LTRPC3G
WO2008143633A2 (en) * 2007-01-10 2008-11-27 University Of Florida Compounds and methods for treatment of alpha-1 antitrypsin deficiency

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Alpha 1-Antitrypsin RN: 9041-92-3 [онлайн] [найдено 2011-04-04] (Найдено из базы данных ChemlDplus). Fregonese L. et al. Hereditary alpha-1-antitrvpsin deficiency and its clinical consequences. Orphanet J Rare Dis. 2008 Jun 19;3:16. [онлайн] [найдено 2011-04-04] Найдено из базы данных PubMed PMID: 18565211. Schmechel DE et al. Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. Neurotoxicology. 2006 Sep; 27(5):637-57. Реферат [онлайн] [найдено 2011-04-05] Найдено из базы данных PubMed PMID: 16870258. Wachter AM et al. Treatment of atopic dermatitis with alpha 1-proteinase inhibitor. Ann Allergy. 1992 Nov; 69(5):407-14. Реферат [онлайн] [найдено 2011-04-05] Найдено из базы данных PubMed PMID: 1456482. Torpy DJ et al. Familial corticosteroid-binding globulin deficiency due to a novel null mutation: association with fatigue and relative hypotension. J Clin Endocrinol Metab. 2001 Aug; 86(8):3692-700. [онлайн] [найдено 2011-04-04] Найдено из базы дан *
Малашенкова И.К. и др. Синдром хронической усталости // Русский медицинский журнал от 17 июня 1997 г., т.5, №12 [онлайн] [найдено 2011-04-05] Найдено из базы данных YANDEX. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2840475C2 (ru) * 2021-05-03 2025-05-26 Ажероникс Са Альфа-1-антитрипсин (ААТ) в лечении и (или) профилактике неврологических нарушений

Also Published As

Publication number Publication date
BRPI1002087B1 (pt) 2019-07-02
PT2289540E (pt) 2012-12-04
NZ585890A (en) 2011-11-25
BRPI1002087A2 (pt) 2012-03-13
EP2289540B1 (en) 2012-08-22
US20100331261A1 (en) 2010-12-30
MX2010006125A (es) 2011-01-05
HK1148198A1 (en) 2011-09-02
JP2011012060A (ja) 2011-01-20
UY32670A (es) 2011-01-31
ES2332645B1 (es) 2010-10-18
AU2010202203B2 (en) 2012-08-23
CL2010000575A1 (es) 2011-10-28
ES2332645A1 (es) 2010-02-09
CA2706212C (en) 2014-02-04
PL2289540T3 (pl) 2013-03-29
CN101934071A (zh) 2011-01-05
ES2392691T3 (es) 2012-12-12
AU2010202203A1 (en) 2011-01-20
CN101934071B (zh) 2012-11-28
JP5231490B2 (ja) 2013-07-10
EP2289540A1 (en) 2011-03-02
CA2706212A1 (en) 2010-12-30
AR077123A1 (es) 2011-08-03
US9205134B2 (en) 2015-12-08

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