RU2420312C2 - Усовершенствования, касающиеся везикул внешней мембраны менингококков - Google Patents
Усовершенствования, касающиеся везикул внешней мембраны менингококков Download PDFInfo
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- RU2420312C2 RU2420312C2 RU2007111838/15A RU2007111838A RU2420312C2 RU 2420312 C2 RU2420312 C2 RU 2420312C2 RU 2007111838/15 A RU2007111838/15 A RU 2007111838/15A RU 2007111838 A RU2007111838 A RU 2007111838A RU 2420312 C2 RU2420312 C2 RU 2420312C2
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- omv
- seropodotype
- meningococci
- meningococcal
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- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical class C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 description 1
- 229960001661 ursodiol Drugs 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0419627.5 | 2004-09-03 | ||
| GBGB0419627.5A GB0419627D0 (en) | 2004-09-03 | 2004-09-03 | Immunogenic bacterial vesicles with outer membrane proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007111838A RU2007111838A (ru) | 2008-10-10 |
| RU2420312C2 true RU2420312C2 (ru) | 2011-06-10 |
Family
ID=33156002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007111838/15A RU2420312C2 (ru) | 2004-09-03 | 2005-09-05 | Усовершенствования, касающиеся везикул внешней мембраны менингококков |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8808711B2 (https=) |
| EP (1) | EP1784213B1 (https=) |
| JP (2) | JP2008511608A (https=) |
| CN (2) | CN101862451A (https=) |
| AU (1) | AU2005278896B2 (https=) |
| BR (1) | BRPI0514883A (https=) |
| CA (1) | CA2578588A1 (https=) |
| ES (1) | ES2527859T3 (https=) |
| GB (1) | GB0419627D0 (https=) |
| MX (1) | MX2007002633A (https=) |
| NZ (1) | NZ553521A (https=) |
| RU (1) | RU2420312C2 (https=) |
| WO (1) | WO2006024946A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
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| GB9513371D0 (en) * | 1995-06-30 | 1995-09-06 | Biocine Spa | Immunogenic detoxified mutant toxins |
| EP2270173B1 (en) | 1999-05-19 | 2016-01-06 | GlaxoSmithKline Biologicals SA | Combination neisserial compositions |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| GB0408977D0 (en) * | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| US10828361B2 (en) * | 2006-03-22 | 2020-11-10 | Glaxosmithkline Biologicals Sa | Regimens for immunisation with meningococcal conjugates |
| PL2004225T3 (pl) | 2006-03-22 | 2012-09-28 | Novartis Ag | Schematy immunizacji koniugatami meningokokowymi |
| WO2009050586A1 (en) | 2007-10-19 | 2009-04-23 | Novartis Ag | Meningococcal vaccine formulations |
| PT2268618E (pt) | 2008-03-03 | 2015-10-12 | Novartis Ag | Compostos e composições moduladores da actividade tlr |
| JP5723768B2 (ja) | 2008-05-30 | 2015-05-27 | ザ ユナイテッド ステイツ オブ アメリカ， アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー， オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ | 髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用 |
| GB0822634D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
| JP2012512240A (ja) | 2008-12-17 | 2012-05-31 | ノバルティス アーゲー | ヘモグロビン受容体を含む髄膜炎菌ワクチン |
| CA2765112A1 (en) | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
| CN102740882A (zh) | 2009-08-27 | 2012-10-17 | 诺华有限公司 | 含有铝、寡核苷酸和聚阳离子的佐剂 |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| SG10201501980SA (en) | 2009-12-15 | 2015-05-28 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| CN102802662A (zh) | 2010-03-18 | 2012-11-28 | 诺华有限公司 | 用于脑膜炎球菌血清组b的含佐剂疫苗 |
| AU2011232421B2 (en) | 2010-03-23 | 2015-08-13 | Novartis Ag | Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
| EP2707009A1 (en) | 2011-05-12 | 2014-03-19 | Novartis AG | Antipyretics to enhance tolerability of vesicle-based vaccines |
| JP5957541B2 (ja) | 2012-02-02 | 2016-07-27 | ノバルティス アーゲー | 髄膜炎菌における増加したタンパク質発現のためのプロモータ |
| JP2015517089A (ja) | 2012-03-08 | 2015-06-18 | ノバルティス アーゲー | タンパク質ベースの髄膜炎菌ワクチンのためのインビトロ有効性アッセイ |
| WO2013151706A2 (en) | 2012-04-06 | 2013-10-10 | Cornell University | Subunit vaccine delivery platform for robust humoral and cellular immune responses |
| MX357538B (es) | 2012-06-14 | 2018-07-13 | Novartis Ag | Vacunas para meningococo de serogrupo x. |
| US9526776B2 (en) | 2012-09-06 | 2016-12-27 | Glaxosmithkline Biologicals Sa | Combination vaccines with serogroup B meningococcus and D/T/P |
| US9764027B2 (en) | 2012-09-18 | 2017-09-19 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
| JP2016507543A (ja) | 2013-02-07 | 2016-03-10 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 小胞を含む医薬組成物 |
| JP6786394B2 (ja) | 2014-02-28 | 2020-11-18 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変髄膜炎菌ｆＨｂｐポリペプチド |
| AU2015289192A1 (en) | 2014-07-17 | 2017-02-02 | Glaxosmithkline Biologicals S.A. | Modified meningococcal fHbp polypeptides |
| KR102626831B1 (ko) * | 2014-07-17 | 2024-01-22 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 수막구균 백신 |
| KR101742236B1 (ko) * | 2014-10-29 | 2017-05-31 | 인하대학교 산학협력단 | 쯔쯔가무시병에 대한 면역 조성물 및 이의 제조방법 |
| CN105669964B (zh) * | 2016-03-04 | 2017-11-21 | 博瑞生物医药（苏州）股份有限公司 | 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用 |
| US12161707B2 (en) | 2016-09-02 | 2024-12-10 | Glaxosmithkline Biologicals Sa | Vaccines for Neisseria gonorrhoeae |
| US11524037B2 (en) | 2017-09-08 | 2022-12-13 | Evelo Biosciences, Inc. | Bacterial extracellular vesicles |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
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| WO2003105890A2 (en) * | 2002-06-13 | 2003-12-24 | Glaxosmithkline Biologicals S.A. | Vaccine composition |
| WO2004079977A2 (en) * | 2003-03-03 | 2004-09-16 | Interdigital Technology Corporation | Optimizing multi-user detection |
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| DE2848965A1 (de) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| DK0624376T3 (da) | 1993-05-13 | 2000-07-24 | American Cyanamid Co | Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci |
| AU2356095A (en) | 1994-04-20 | 1995-11-29 | U.S. Department Of The Army | Vaccine against gram-negative bacterial infections |
| US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
| PL338146A1 (en) | 1997-07-17 | 2000-09-25 | North American Vaccine | Immunogenic complex combinations consisting of meningococcal porine of b group and h. influenzae polysaccharide |
| BR9910749A (pt) | 1998-05-29 | 2001-02-13 | Chiron Corp | Composições e vacinas imunogênicas combinadas para meningites b e c e método de induzir uma resposta imune por administração da mesma |
| EP1741443B1 (en) | 1998-05-29 | 2014-05-21 | Novartis Vaccines and Diagnostics, Inc. | Combination meningitidis B/C vaccines |
| GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| WO2001034642A2 (en) | 1999-11-12 | 2001-05-17 | University Of Iowa Research Foundation | Control of neisserial membrane synthesis |
| NO20002828D0 (no) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav |
| US6936261B2 (en) | 2000-07-27 | 2005-08-30 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
| CA2452720C (en) * | 2001-07-26 | 2012-04-17 | Chiron S.R.L. | Vaccines comprising aluminium adjuvants and histidine |
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| EP1524991A1 (en) * | 2002-08-02 | 2005-04-27 | GlaxoSmithKline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
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| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
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-
2004
- 2004-09-03 GB GBGB0419627.5A patent/GB0419627D0/en not_active Ceased
-
2005
- 2005-09-05 NZ NZ553521A patent/NZ553521A/en not_active IP Right Cessation
- 2005-09-05 WO PCT/IB2005/002801 patent/WO2006024946A2/en not_active Ceased
- 2005-09-05 ES ES05782411.2T patent/ES2527859T3/es not_active Expired - Lifetime
- 2005-09-05 US US11/661,996 patent/US8808711B2/en not_active Expired - Fee Related
- 2005-09-05 EP EP05782411.2A patent/EP1784213B1/en not_active Expired - Lifetime
- 2005-09-05 CN CN201010169356A patent/CN101862451A/zh active Pending
- 2005-09-05 BR BRPI0514883-9A patent/BRPI0514883A/pt not_active IP Right Cessation
- 2005-09-05 CA CA002578588A patent/CA2578588A1/en not_active Abandoned
- 2005-09-05 AU AU2005278896A patent/AU2005278896B2/en not_active Ceased
- 2005-09-05 MX MX2007002633A patent/MX2007002633A/es active IP Right Grant
- 2005-09-05 RU RU2007111838/15A patent/RU2420312C2/ru not_active IP Right Cessation
- 2005-09-05 JP JP2007529033A patent/JP2008511608A/ja active Pending
- 2005-09-05 CN CNA2005800294697A patent/CN101115501A/zh active Pending
-
2011
- 2011-08-26 JP JP2011185225A patent/JP2011236254A/ja active Pending
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| WO2003105890A2 (en) * | 2002-06-13 | 2003-12-24 | Glaxosmithkline Biologicals S.A. | Vaccine composition |
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| ESTER D. et al. Immunogenicity and safety of hexavalent meningococcal outer-membrane-vesicle vaccine in children of 2-3 and 7-8 years of age, Vaccine, 2000, v.18, №15, p.1456-1466, abstract. SEXTON С.et al., The New Zealand meningococcal vaccine strategy: A tailor-made vaccine to combat a devastating epidemic, The New Zealand Medical Journal, 2004, v.117, №1200, доступно он-лайн://www.nzma.org.nz/journal/117-1200/1015. BAKKE H. et al. Meningococcal outer membrane vesicle vaccine given intranasally can induce immunological memory and booster responses without evidence of tolerance. Infection and Immunity, 2001, v.69, №6, p.5010-5015. * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2527859T3 (es) | 2015-01-30 |
| AU2005278896A1 (en) | 2006-03-09 |
| CN101862451A (zh) | 2010-10-20 |
| JP2011236254A (ja) | 2011-11-24 |
| EP1784213A2 (en) | 2007-05-16 |
| EP1784213B1 (en) | 2014-10-29 |
| BRPI0514883A (pt) | 2008-06-24 |
| JP2008511608A (ja) | 2008-04-17 |
| US20080063665A1 (en) | 2008-03-13 |
| NZ553521A (en) | 2010-01-29 |
| GB0419627D0 (en) | 2004-10-06 |
| MX2007002633A (es) | 2007-05-15 |
| AU2005278896B2 (en) | 2011-12-22 |
| CA2578588A1 (en) | 2006-03-09 |
| WO2006024946A2 (en) | 2006-03-09 |
| WO2006024946A3 (en) | 2006-11-30 |
| RU2007111838A (ru) | 2008-10-10 |
| CN101115501A (zh) | 2008-01-30 |
| US8808711B2 (en) | 2014-08-19 |
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| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20140906 |