JP2008511608A - 髄膜炎菌外膜ベシクルに関する改良 - Google Patents

髄膜炎菌外膜ベシクルに関する改良 Download PDF

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Publication number
JP2008511608A
JP2008511608A JP2007529033A JP2007529033A JP2008511608A JP 2008511608 A JP2008511608 A JP 2008511608A JP 2007529033 A JP2007529033 A JP 2007529033A JP 2007529033 A JP2007529033 A JP 2007529033A JP 2008511608 A JP2008511608 A JP 2008511608A
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omv
composition
meningococcal
serum
subtype
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JP2008511608A5 (https=
Inventor
フィリップ オステル，
リノ ラプッオリ，
マリアグラツィア ピッツァ，
Original Assignee
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル
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Publication of JP2008511608A publication Critical patent/JP2008511608A/ja
Publication of JP2008511608A5 publication Critical patent/JP2008511608A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
JP2007529033A 2004-09-03 2005-09-05 髄膜炎菌外膜ベシクルに関する改良 Pending JP2008511608A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0419627.5A GB0419627D0 (en) 2004-09-03 2004-09-03 Immunogenic bacterial vesicles with outer membrane proteins
PCT/IB2005/002801 WO2006024946A2 (en) 2004-09-03 2005-09-05 Improvements relating to meningococcal outer membrane vesicles

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011185225A Division JP2011236254A (ja) 2004-09-03 2011-08-26 髄膜炎菌外膜ベシクルに関する改良

Publications (2)

Publication Number Publication Date
JP2008511608A true JP2008511608A (ja) 2008-04-17
JP2008511608A5 JP2008511608A5 (https=) 2011-10-13

Family

ID=33156002

Family Applications (2)

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JP2007529033A Pending JP2008511608A (ja) 2004-09-03 2005-09-05 髄膜炎菌外膜ベシクルに関する改良
JP2011185225A Pending JP2011236254A (ja) 2004-09-03 2011-08-26 髄膜炎菌外膜ベシクルに関する改良

Family Applications After (1)

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JP2011185225A Pending JP2011236254A (ja) 2004-09-03 2011-08-26 髄膜炎菌外膜ベシクルに関する改良

Country Status (13)

Country Link
US (1) US8808711B2 (https=)
EP (1) EP1784213B1 (https=)
JP (2) JP2008511608A (https=)
CN (2) CN101862451A (https=)
AU (1) AU2005278896B2 (https=)
BR (1) BRPI0514883A (https=)
CA (1) CA2578588A1 (https=)
ES (1) ES2527859T3 (https=)
GB (1) GB0419627D0 (https=)
MX (1) MX2007002633A (https=)
NZ (1) NZ553521A (https=)
RU (1) RU2420312C2 (https=)
WO (1) WO2006024946A2 (https=)

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GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
US10828361B2 (en) * 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
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WO2009050586A1 (en) 2007-10-19 2009-04-23 Novartis Ag Meningococcal vaccine formulations
PT2268618E (pt) 2008-03-03 2015-10-12 Novartis Ag Compostos e composições moduladores da actividade tlr
JP5723768B2 (ja) 2008-05-30 2015-05-27 ザ ユナイテッド ステイツ オブ アメリカ， アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー， オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ 髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用
GB0822634D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
JP2012512240A (ja) 2008-12-17 2012-05-31 ノバルティス アーゲー ヘモグロビン受容体を含む髄膜炎菌ワクチン
CA2765112A1 (en) 2009-06-10 2010-12-16 Novartis Ag Benzonaphthyridine-containing vaccines
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
ES2443952T3 (es) 2009-09-02 2014-02-21 Novartis Ag Composiciones inmunógenas que incluyen moduladores de la actividad de TLR
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
SG10201501980SA (en) 2009-12-15 2015-05-28 Novartis Ag Homogeneous suspension of immunopotentiating compounds and uses thereof
CN102802662A (zh) 2010-03-18 2012-11-28 诺华有限公司 用于脑膜炎球菌血清组b的含佐剂疫苗
AU2011232421B2 (en) 2010-03-23 2015-08-13 Novartis Ag Compounds (cystein based lipopeptides) and compositions as TLR2 agonists used for treating infections, inflammations, respiratory diseases etc.
BR112013005626B1 (pt) 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
EP2707009A1 (en) 2011-05-12 2014-03-19 Novartis AG Antipyretics to enhance tolerability of vesicle-based vaccines
JP5957541B2 (ja) 2012-02-02 2016-07-27 ノバルティス アーゲー 髄膜炎菌における増加したタンパク質発現のためのプロモータ
JP2015517089A (ja) 2012-03-08 2015-06-18 ノバルティス アーゲー タンパク質ベースの髄膜炎菌ワクチンのためのインビトロ有効性アッセイ
WO2013151706A2 (en) 2012-04-06 2013-10-10 Cornell University Subunit vaccine delivery platform for robust humoral and cellular immune responses
MX357538B (es) 2012-06-14 2018-07-13 Novartis Ag Vacunas para meningococo de serogrupo x.
US9526776B2 (en) 2012-09-06 2016-12-27 Glaxosmithkline Biologicals Sa Combination vaccines with serogroup B meningococcus and D/T/P
US9764027B2 (en) 2012-09-18 2017-09-19 Glaxosmithkline Biologicals Sa Outer membrane vesicles
JP2016507543A (ja) 2013-02-07 2016-03-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 小胞を含む医薬組成物
JP6786394B2 (ja) 2014-02-28 2020-11-18 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変髄膜炎菌ｆＨｂｐポリペプチド
AU2015289192A1 (en) 2014-07-17 2017-02-02 Glaxosmithkline Biologicals S.A. Modified meningococcal fHbp polypeptides
KR102626831B1 (ko) * 2014-07-17 2024-01-22 글락소스미스클라인 바이오로지칼즈 에스.에이. 수막구균 백신
KR101742236B1 (ko) * 2014-10-29 2017-05-31 인하대학교 산학협력단 쯔쯔가무시병에 대한 면역 조성물 및 이의 제조방법
CN105669964B (zh) * 2016-03-04 2017-11-21 博瑞生物医药（苏州）股份有限公司 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用
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GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay

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Also Published As

Publication number Publication date
ES2527859T3 (es) 2015-01-30
AU2005278896A1 (en) 2006-03-09
CN101862451A (zh) 2010-10-20
JP2011236254A (ja) 2011-11-24
EP1784213A2 (en) 2007-05-16
EP1784213B1 (en) 2014-10-29
BRPI0514883A (pt) 2008-06-24
RU2420312C2 (ru) 2011-06-10
US20080063665A1 (en) 2008-03-13
NZ553521A (en) 2010-01-29
GB0419627D0 (en) 2004-10-06
MX2007002633A (es) 2007-05-15
AU2005278896B2 (en) 2011-12-22
CA2578588A1 (en) 2006-03-09
WO2006024946A2 (en) 2006-03-09
WO2006024946A3 (en) 2006-11-30
RU2007111838A (ru) 2008-10-10
CN101115501A (zh) 2008-01-30
US8808711B2 (en) 2014-08-19

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