RU2404758C2 - Способы повышения биологической доступности ингибитора ренина - Google Patents
Способы повышения биологической доступности ингибитора ренина Download PDFInfo
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- RU2404758C2 RU2404758C2 RU2007107850/15A RU2007107850A RU2404758C2 RU 2404758 C2 RU2404758 C2 RU 2404758C2 RU 2007107850/15 A RU2007107850/15 A RU 2007107850/15A RU 2007107850 A RU2007107850 A RU 2007107850A RU 2404758 C2 RU2404758 C2 RU 2404758C2
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- inhibitor
- amino
- hydroxy
- amide
- derivative
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US60/598,700 | 2004-08-03 |
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| NO (1) | NO20071142L (https=) |
| NZ (1) | NZ552903A (https=) |
| PE (1) | PE20060416A1 (https=) |
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| SI (1) | SI1776099T1 (https=) |
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| WO (1) | WO2006013094A1 (https=) |
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| EP1891937A1 (en) * | 2006-08-25 | 2008-02-27 | Novartis AG | Galenic formulations of aliskiren |
| EP1927350A1 (en) * | 2006-11-24 | 2008-06-04 | Novartis AG | Methods for improving bioavailability of a renin inhibitor |
| CA2769392A1 (en) | 2009-07-31 | 2011-02-03 | Sandoz Ag | Method for the preparation of w-amino-alkaneamides and w-amino-alkanethioamides as well as intermediates of this method |
| WO2012010651A2 (en) | 2010-07-23 | 2012-01-26 | Sandoz Ag | Method for the preparation of omega-amino-alkaneamides and omega-amino-alkanethioamides as well as intermediates of this method |
| WO2014168255A1 (ja) * | 2013-04-12 | 2014-10-16 | 国立大学法人京都大学 | 巨核球の成熟化促進物質 |
| WO2015035218A1 (en) * | 2013-09-05 | 2015-03-12 | Howard University | Method of increasing the bioavailability of an hiv drug |
| JP6029621B2 (ja) * | 2014-07-14 | 2016-11-24 | ヤマサ醤油株式会社 | 血漿レニン活性の測定法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5559111A (en) * | 1994-04-18 | 1996-09-24 | Ciba-Geigy Corporation | δ-amino-γ-hydroxy-ω-aryl-alkanoic acid amides |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| WO2001058470A2 (en) * | 2000-02-11 | 2001-08-16 | Praecis Pharmaceuticals Incorporated | Methods for enhancing the bioavailability of a drug |
| RU2197967C2 (ru) * | 1997-08-14 | 2003-02-10 | Авентис Фармасьютикалз, Инк. | Способ повышения биологической доступности фексофенадина и его производных |
Family Cites Families (13)
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|---|---|---|---|---|
| IL108499A (en) | 1993-02-04 | 2000-02-29 | Lilly Co Eli | Mammalian influx peptide transporter |
| US5567592A (en) | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| CA2224227A1 (en) | 1995-06-07 | 1996-12-19 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| US5716928A (en) * | 1995-06-07 | 1998-02-10 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| JP2003512443A (ja) * | 1999-10-27 | 2003-04-02 | ベーカー ノートン ファーマシューティカルズ インコーポレイテッド | タキサンをヒト患者に経口投与するための方法及び組成物 |
| WO2001092468A2 (en) * | 2000-05-31 | 2001-12-06 | Rutgers, The State University Of New Jersey | Novel compositions for the expression of the human peptide histidine transporter 1 and methods of use thereof |
| US7115565B2 (en) * | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| GB0113663D0 (en) * | 2001-06-05 | 2001-07-25 | Novartis Ag | Use of organic compounds |
| KR20040066177A (ko) | 2001-12-19 | 2004-07-23 | 알자 코포레이션 | 친수성 거대분자의 경구 생체이용률을 증가시키기 위한제형 및 투여 형태 |
| US6869970B2 (en) * | 2002-02-04 | 2005-03-22 | Novartis Ag | Crystalline salt forms of valsartan |
| EP1501546B1 (de) * | 2002-05-03 | 2012-10-10 | Hexal AG | Stabile pharmazeutische formulierung für eine kombination aus einem statin mit einem ace-hemmer |
| PT1517682E (pt) * | 2002-06-28 | 2007-02-28 | Speedel Pharma Ag | Formulação farmacêutica compreendendo inibidor da renina não-peptídico e tensioactivo |
| NZ549535A (en) * | 2004-03-17 | 2010-11-26 | Novartis Ag | Use of aliskiren for treating renal and other disorders |
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- 2005-08-01 PE PE2005000883A patent/PE20060416A1/es not_active Application Discontinuation
- 2005-08-02 BR BRPI0514021-8A patent/BRPI0514021A/pt not_active IP Right Cessation
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- 2005-08-02 US US11/572,471 patent/US7709532B2/en not_active Expired - Fee Related
- 2005-08-02 MX MX2007001339A patent/MX2007001339A/es active IP Right Grant
- 2005-08-02 DE DE602005017905T patent/DE602005017905D1/de not_active Expired - Lifetime
- 2005-08-02 DK DK05769973.8T patent/DK1776099T3/da active
- 2005-08-02 AT AT05769973T patent/ATE449601T1/de active
- 2005-08-02 EP EP05769973A patent/EP1776099B1/en not_active Expired - Lifetime
- 2005-08-02 AU AU2005268844A patent/AU2005268844B2/en not_active Ceased
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- 2005-08-02 RU RU2007107850/15A patent/RU2404758C2/ru not_active IP Right Cessation
- 2005-08-02 PT PT05769973T patent/PT1776099E/pt unknown
- 2005-08-02 CA CA2572743A patent/CA2572743C/en not_active Expired - Fee Related
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- 2005-08-02 MY MYPI20053584A patent/MY142180A/en unknown
- 2005-08-02 ES ES05769973T patent/ES2335597T3/es not_active Expired - Lifetime
- 2005-08-02 KR KR1020077002718A patent/KR20070040384A/ko not_active Abandoned
- 2005-08-02 EP EP09014648A patent/EP2191823A1/en not_active Withdrawn
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2006
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- 2007-01-11 IL IL180678A patent/IL180678A/en not_active IP Right Cessation
- 2007-01-15 EC EC2007007169A patent/ECSP077169A/es unknown
- 2007-02-02 TN TNP2007000038A patent/TNSN07038A1/en unknown
- 2007-02-22 MA MA29709A patent/MA28821B1/fr unknown
- 2007-02-28 NO NO20071142A patent/NO20071142L/no not_active Application Discontinuation
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5559111A (en) * | 1994-04-18 | 1996-09-24 | Ciba-Geigy Corporation | δ-amino-γ-hydroxy-ω-aryl-alkanoic acid amides |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| RU2197967C2 (ru) * | 1997-08-14 | 2003-02-10 | Авентис Фармасьютикалз, Инк. | Способ повышения биологической доступности фексофенадина и его производных |
| WO2001058470A2 (en) * | 2000-02-11 | 2001-08-16 | Praecis Pharmaceuticals Incorporated | Methods for enhancing the bioavailability of a drug |
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| GRUBER A "A phase I/II study of the MDR modulator Valspodar (PSC 833) combined with daunorubicin and cytarabine in patients with relapsed and primary refractory acute myeloid leukemia" Leukemia research, 2003 Арr; 27(4):323-8, реферат [Найдено 25.05.2009] Medline [он-лайн]РМID: 12531223. * |
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