JP5134366B2 - レニン阻害剤のバイオアベイラビリティーの改善法 - Google Patents
レニン阻害剤のバイオアベイラビリティーの改善法 Download PDFInfo
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- JP5134366B2 JP5134366B2 JP2007524264A JP2007524264A JP5134366B2 JP 5134366 B2 JP5134366 B2 JP 5134366B2 JP 2007524264 A JP2007524264 A JP 2007524264A JP 2007524264 A JP2007524264 A JP 2007524264A JP 5134366 B2 JP5134366 B2 JP 5134366B2
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- inhibitor
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- alkanoic acid
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
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- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
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- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
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- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US59870004P | 2004-08-03 | 2004-08-03 | |
| US60/598,700 | 2004-08-03 | ||
| PCT/EP2005/008369 WO2006013094A1 (en) | 2004-08-03 | 2005-08-02 | Methods for improving bioavailability of a renin inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008508340A JP2008508340A (ja) | 2008-03-21 |
| JP2008508340A5 JP2008508340A5 (https=) | 2008-09-11 |
| JP5134366B2 true JP5134366B2 (ja) | 2013-01-30 |
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| JP2007524264A Expired - Fee Related JP5134366B2 (ja) | 2004-08-03 | 2005-08-02 | レニン阻害剤のバイオアベイラビリティーの改善法 |
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| US (1) | US7709532B2 (https=) |
| EP (2) | EP1776099B1 (https=) |
| JP (1) | JP5134366B2 (https=) |
| KR (1) | KR20070040384A (https=) |
| CN (1) | CN1993116B (https=) |
| AR (1) | AR050043A1 (https=) |
| AT (1) | ATE449601T1 (https=) |
| AU (1) | AU2005268844B2 (https=) |
| BR (1) | BRPI0514021A (https=) |
| CA (1) | CA2572743C (https=) |
| CY (1) | CY1109826T1 (https=) |
| DE (1) | DE602005017905D1 (https=) |
| DK (1) | DK1776099T3 (https=) |
| EC (1) | ECSP077169A (https=) |
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| HR (1) | HRP20100064T1 (https=) |
| IL (1) | IL180678A (https=) |
| MA (1) | MA28821B1 (https=) |
| MX (1) | MX2007001339A (https=) |
| MY (1) | MY142180A (https=) |
| NO (1) | NO20071142L (https=) |
| NZ (1) | NZ552903A (https=) |
| PE (1) | PE20060416A1 (https=) |
| PL (1) | PL1776099T3 (https=) |
| PT (1) | PT1776099E (https=) |
| RU (1) | RU2404758C2 (https=) |
| SI (1) | SI1776099T1 (https=) |
| TN (1) | TNSN07038A1 (https=) |
| TW (1) | TW200616610A (https=) |
| WO (1) | WO2006013094A1 (https=) |
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| EP1891937A1 (en) * | 2006-08-25 | 2008-02-27 | Novartis AG | Galenic formulations of aliskiren |
| EP1927350A1 (en) * | 2006-11-24 | 2008-06-04 | Novartis AG | Methods for improving bioavailability of a renin inhibitor |
| CA2769392A1 (en) | 2009-07-31 | 2011-02-03 | Sandoz Ag | Method for the preparation of w-amino-alkaneamides and w-amino-alkanethioamides as well as intermediates of this method |
| WO2012010651A2 (en) | 2010-07-23 | 2012-01-26 | Sandoz Ag | Method for the preparation of omega-amino-alkaneamides and omega-amino-alkanethioamides as well as intermediates of this method |
| WO2014168255A1 (ja) * | 2013-04-12 | 2014-10-16 | 国立大学法人京都大学 | 巨核球の成熟化促進物質 |
| WO2015035218A1 (en) * | 2013-09-05 | 2015-03-12 | Howard University | Method of increasing the bioavailability of an hiv drug |
| JP6029621B2 (ja) * | 2014-07-14 | 2016-11-24 | ヤマサ醤油株式会社 | 血漿レニン活性の測定法 |
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| IL108499A (en) | 1993-02-04 | 2000-02-29 | Lilly Co Eli | Mammalian influx peptide transporter |
| US5567592A (en) | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
| CA2224227A1 (en) | 1995-06-07 | 1996-12-19 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| US5716928A (en) * | 1995-06-07 | 1998-02-10 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| CN1143680C (zh) * | 1997-08-14 | 2004-03-31 | 阿旺蒂斯制药公司 | 增强非索非那定及其衍生物之生物利用度的方法 |
| JP2003512443A (ja) * | 1999-10-27 | 2003-04-02 | ベーカー ノートン ファーマシューティカルズ インコーポレイテッド | タキサンをヒト患者に経口投与するための方法及び組成物 |
| AU3808801A (en) * | 2000-02-11 | 2001-08-20 | Praecis Pharmaceuticals Incorporated | Methods for enhancing the bioavailability of a drug |
| WO2001092468A2 (en) * | 2000-05-31 | 2001-12-06 | Rutgers, The State University Of New Jersey | Novel compositions for the expression of the human peptide histidine transporter 1 and methods of use thereof |
| US7115565B2 (en) * | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| GB0113663D0 (en) * | 2001-06-05 | 2001-07-25 | Novartis Ag | Use of organic compounds |
| KR20040066177A (ko) | 2001-12-19 | 2004-07-23 | 알자 코포레이션 | 친수성 거대분자의 경구 생체이용률을 증가시키기 위한제형 및 투여 형태 |
| US6869970B2 (en) * | 2002-02-04 | 2005-03-22 | Novartis Ag | Crystalline salt forms of valsartan |
| EP1501546B1 (de) * | 2002-05-03 | 2012-10-10 | Hexal AG | Stabile pharmazeutische formulierung für eine kombination aus einem statin mit einem ace-hemmer |
| PT1517682E (pt) * | 2002-06-28 | 2007-02-28 | Speedel Pharma Ag | Formulação farmacêutica compreendendo inibidor da renina não-peptídico e tensioactivo |
| NZ549535A (en) * | 2004-03-17 | 2010-11-26 | Novartis Ag | Use of aliskiren for treating renal and other disorders |
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- 2005-08-02 WO PCT/EP2005/008369 patent/WO2006013094A1/en not_active Ceased
- 2005-08-02 JP JP2007524264A patent/JP5134366B2/ja not_active Expired - Fee Related
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- 2005-08-02 TW TW094126194A patent/TW200616610A/zh unknown
- 2005-08-02 RU RU2007107850/15A patent/RU2404758C2/ru not_active IP Right Cessation
- 2005-08-02 PT PT05769973T patent/PT1776099E/pt unknown
- 2005-08-02 CA CA2572743A patent/CA2572743C/en not_active Expired - Fee Related
- 2005-08-02 HR HR20100064T patent/HRP20100064T1/hr unknown
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- 2005-08-02 KR KR1020077002718A patent/KR20070040384A/ko not_active Abandoned
- 2005-08-02 EP EP09014648A patent/EP2191823A1/en not_active Withdrawn
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2006
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2007
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- 2007-02-28 NO NO20071142A patent/NO20071142L/no not_active Application Discontinuation
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