PT1776099E - Métodos para melhoramento da biodisponibilidade de um inibidor de renina - Google Patents

Métodos para melhoramento da biodisponibilidade de um inibidor de renina Download PDF

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Publication number
PT1776099E
PT1776099E PT05769973T PT05769973T PT1776099E PT 1776099 E PT1776099 E PT 1776099E PT 05769973 T PT05769973 T PT 05769973T PT 05769973 T PT05769973 T PT 05769973T PT 1776099 E PT1776099 E PT 1776099E
Authority
PT
Portugal
Prior art keywords
methods
renin inhibitor
improving bioavailability
bioavailability
improving
Prior art date
Application number
PT05769973T
Other languages
English (en)
Inventor
Gerhard Gross
Gian P Camenisch
Isabel Ottinger
Daniel Wasmuth
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35056890&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1776099(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1776099E publication Critical patent/PT1776099E/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT05769973T 2004-08-03 2005-08-02 Métodos para melhoramento da biodisponibilidade de um inibidor de renina PT1776099E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59870004P 2004-08-03 2004-08-03

Publications (1)

Publication Number Publication Date
PT1776099E true PT1776099E (pt) 2010-01-06

Family

ID=35056890

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05769973T PT1776099E (pt) 2004-08-03 2005-08-02 Métodos para melhoramento da biodisponibilidade de um inibidor de renina

Country Status (31)

Country Link
US (1) US7709532B2 (pt)
EP (2) EP1776099B1 (pt)
JP (1) JP5134366B2 (pt)
KR (1) KR20070040384A (pt)
CN (1) CN1993116B (pt)
AR (1) AR050043A1 (pt)
AT (1) ATE449601T1 (pt)
AU (1) AU2005268844B2 (pt)
BR (1) BRPI0514021A (pt)
CA (1) CA2572743C (pt)
CY (1) CY1109826T1 (pt)
DE (1) DE602005017905D1 (pt)
DK (1) DK1776099T3 (pt)
EC (1) ECSP077169A (pt)
ES (1) ES2335597T3 (pt)
HR (1) HRP20100064T1 (pt)
IL (1) IL180678A (pt)
MA (1) MA28821B1 (pt)
MX (1) MX2007001339A (pt)
MY (1) MY142180A (pt)
NO (1) NO20071142L (pt)
NZ (1) NZ552903A (pt)
PE (1) PE20060416A1 (pt)
PL (1) PL1776099T3 (pt)
PT (1) PT1776099E (pt)
RU (1) RU2404758C2 (pt)
SI (1) SI1776099T1 (pt)
TN (1) TNSN07038A1 (pt)
TW (1) TW200616610A (pt)
WO (1) WO2006013094A1 (pt)
ZA (1) ZA200610639B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1891937A1 (en) * 2006-08-25 2008-02-27 Novartis AG Galenic formulations of aliskiren
EP1927350A1 (en) * 2006-11-24 2008-06-04 Novartis AG Methods for improving bioavailability of a renin inhibitor
CA2769392A1 (en) 2009-07-31 2011-02-03 Sandoz Ag Method for the preparation of w-amino-alkaneamides and w-amino-alkanethioamides as well as intermediates of this method
WO2012010651A2 (en) 2010-07-23 2012-01-26 Sandoz Ag Method for the preparation of omega-amino-alkaneamides and omega-amino-alkanethioamides as well as intermediates of this method
WO2014168255A1 (ja) * 2013-04-12 2014-10-16 国立大学法人京都大学 巨核球の成熟化促進物質
WO2015035218A1 (en) * 2013-09-05 2015-03-12 Howard University Method of increasing the bioavailability of an hiv drug
JP6029621B2 (ja) * 2014-07-14 2016-11-24 ヤマサ醤油株式会社 血漿レニン活性の測定法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL108499A (en) 1993-02-04 2000-02-29 Lilly Co Eli Mammalian influx peptide transporter
US5567592A (en) * 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
CA2224227A1 (en) 1995-06-07 1996-12-19 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5716928A (en) * 1995-06-07 1998-02-10 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
IL149360A0 (en) * 1999-10-27 2002-11-10 Baker Norton Pharma Method and compositions for administering taxanes orally to human patients
WO2001058470A2 (en) * 2000-02-11 2001-08-16 Praecis Pharmaceuticals Incorporated Methods for enhancing the bioavailability of a drug
AU2001271281A1 (en) * 2000-05-31 2001-12-11 Rutgers, The State University Of New Jersey Novel compositions for the expression of the human peptide histidine transporter1 and methods of use thereof
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
GB0113663D0 (en) * 2001-06-05 2001-07-25 Novartis Ag Use of organic compounds
HUP0402451A3 (en) 2001-12-19 2008-04-28 Alza Corp Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
US6869970B2 (en) * 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
US20040137054A1 (en) * 2002-05-03 2004-07-15 Alexandra Hager Stable pharmaceutical formulation for a combination of a statin and an ace-inhibitors
DE60309472T2 (de) * 2002-06-28 2007-06-28 Speedel Pharma Ag Pharmazeutische formulierung mit einem nicht peptidischen renin-hemmer und surfactant
US20080161321A1 (en) 2004-03-17 2008-07-03 David Louis Feldman Use of Renin Inhibitors in Therapy

Also Published As

Publication number Publication date
TW200616610A (en) 2006-06-01
AU2005268844A1 (en) 2006-02-09
MX2007001339A (es) 2007-03-27
CN1993116B (zh) 2011-04-13
ZA200610639B (en) 2008-05-28
AU2005268844B2 (en) 2009-03-05
IL180678A (en) 2011-04-28
PE20060416A1 (es) 2006-06-09
RU2404758C2 (ru) 2010-11-27
MA28821B1 (fr) 2007-08-01
CA2572743C (en) 2012-12-04
CA2572743A1 (en) 2006-02-09
DK1776099T3 (da) 2010-03-01
AR050043A1 (es) 2006-09-20
JP2008508340A (ja) 2008-03-21
DE602005017905D1 (de) 2010-01-07
BRPI0514021A (pt) 2008-05-27
SI1776099T1 (sl) 2010-03-31
US7709532B2 (en) 2010-05-04
US20080108703A1 (en) 2008-05-08
PL1776099T3 (pl) 2010-05-31
WO2006013094A1 (en) 2006-02-09
HRP20100064T1 (hr) 2010-03-31
IL180678A0 (en) 2008-03-20
EP2191823A1 (en) 2010-06-02
CN1993116A (zh) 2007-07-04
KR20070040384A (ko) 2007-04-16
EP1776099A1 (en) 2007-04-25
ECSP077169A (es) 2007-02-28
RU2007107850A (ru) 2008-09-10
JP5134366B2 (ja) 2013-01-30
TNSN07038A1 (en) 2008-06-02
NZ552903A (en) 2010-09-30
ATE449601T1 (de) 2009-12-15
NO20071142L (no) 2007-04-26
MY142180A (en) 2010-10-15
EP1776099B1 (en) 2009-11-25
CY1109826T1 (el) 2014-09-10
ES2335597T3 (es) 2010-03-30

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