RU2393167C2 - Пептидные соединения - Google Patents
Пептидные соединения Download PDFInfo
- Publication number
- RU2393167C2 RU2393167C2 RU2006144279/04A RU2006144279A RU2393167C2 RU 2393167 C2 RU2393167 C2 RU 2393167C2 RU 2006144279/04 A RU2006144279/04 A RU 2006144279/04A RU 2006144279 A RU2006144279 A RU 2006144279A RU 2393167 C2 RU2393167 C2 RU 2393167C2
- Authority
- RU
- Russia
- Prior art keywords
- peptide
- compound
- compound according
- cyanine dye
- groups
- Prior art date
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/126—Tetrapeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
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- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| NO20042523 | 2004-06-16 |
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| RU2006144279A RU2006144279A (ru) | 2008-07-27 |
| RU2393167C2 true RU2393167C2 (ru) | 2010-06-27 |
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|---|---|
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| EP (1) | EP1765863B1 (enExample) |
| JP (1) | JP5280683B2 (enExample) |
| CN (2) | CN101001870A (enExample) |
| AT (1) | ATE538135T1 (enExample) |
| BR (1) | BRPI0512209A (enExample) |
| ES (1) | ES2376557T3 (enExample) |
| PL (1) | PL1765863T3 (enExample) |
| RU (1) | RU2393167C2 (enExample) |
| WO (1) | WO2005123768A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014055253A1 (en) * | 2012-10-04 | 2014-04-10 | The General Hospital Corporation | Methods of synthesizing and using peg-like fluorochromes |
| RU2680068C2 (ru) * | 2013-09-02 | 2019-02-14 | Л'Ореаль | Способ окрашивания кератиновых волокон с применением катионных стириловых дисульфидных красителей и композиция, содержащая указанные красители |
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|---|---|---|---|---|
| CN1622830A (zh) * | 2001-07-10 | 2005-06-01 | 安盛药业有限公司 | 肽基化合物 |
| AU2005307195A1 (en) * | 2004-11-22 | 2006-05-26 | Ge Healthcare As | Contrast agents to target extracellular matrix |
| ITMI20050328A1 (it) | 2005-03-03 | 2006-09-04 | Univ Degli Studi Milano | Composti peptidomimetrici e preparazione di derivati biologicamente attivi |
| GB0718967D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Peptide imaging agents |
| GB0718957D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Optical imaging agents |
| EP3673922A1 (en) * | 2008-03-14 | 2020-07-01 | VisEn Medical, Inc. | Integrin targeting agents and methods of using same |
| US20100291706A1 (en) * | 2009-05-15 | 2010-11-18 | Millipore Corporation | Dye conjugates and methods of use |
| EP2314597B1 (en) * | 2009-10-21 | 2012-11-28 | Cyanagen Srl | Kit and method for the labelling of biomolecules |
| GB201010878D0 (en) | 2010-06-29 | 2010-08-11 | Ge Healthcare As | Dye compositiion and dye syntheses |
| EP2588541A1 (en) | 2010-06-29 | 2013-05-08 | GE Healthcare AS | Dye compositions and dye syntheses |
| CN104470546B (zh) * | 2012-07-20 | 2018-02-27 | 佳能株式会社 | 化合物和含有所述化合物的光声成像造影剂 |
| CN107022350A (zh) * | 2017-04-20 | 2017-08-08 | 深圳大学 | 一种荧光造影材料及其制备方法与应用 |
| CN107739528A (zh) * | 2017-09-30 | 2018-02-27 | 武汉工程大学 | 一种五肽改性菁染料化合物及其制备方法和应用 |
| IL287989B2 (en) | 2019-05-13 | 2025-07-01 | Bracco Imaging Spa | Modified cyanine dyes and their conjugates |
| WO2021200259A1 (ja) * | 2020-03-30 | 2021-10-07 | 一丸ファルコス株式会社 | Ｖｉｐｒ２アンタゴニストペプチド |
| CN116917738A (zh) | 2021-04-07 | 2023-10-20 | 贝克顿·迪金森公司 | 水溶性荧光聚合物染料 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001077145A2 (en) * | 2000-04-12 | 2001-10-18 | Amersham Health As | Integrin binding peptide derivatives |
| WO2003006491A2 (en) * | 2001-07-10 | 2003-01-23 | Amersham Health As | Peptide-based compounds for targeting intergin receptors |
| RU2001129707A (ru) * | 1999-04-09 | 2003-09-27 | Институт Фюр Диагностикфоршунг Гмбх Ан Дер Фрайен Универзитэт Берлин (De) | Окрашенные коньюгаты пептидовв, имеющих короткую цепь, используемые в качестве анионов |
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| DE4445065A1 (de) * | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
| NO20033115D0 (no) * | 2003-07-08 | 2003-07-08 | Amersham Health As | Peptid-baserte forbindelser |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2001129707A (ru) * | 1999-04-09 | 2003-09-27 | Институт Фюр Диагностикфоршунг Гмбх Ан Дер Фрайен Универзитэт Берлин (De) | Окрашенные коньюгаты пептидовв, имеющих короткую цепь, используемые в качестве анионов |
| WO2001077145A2 (en) * | 2000-04-12 | 2001-10-18 | Amersham Health As | Integrin binding peptide derivatives |
| WO2003006491A2 (en) * | 2001-07-10 | 2003-01-23 | Amersham Health As | Peptide-based compounds for targeting intergin receptors |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014055253A1 (en) * | 2012-10-04 | 2014-04-10 | The General Hospital Corporation | Methods of synthesizing and using peg-like fluorochromes |
| RU2680068C2 (ru) * | 2013-09-02 | 2019-02-14 | Л'Ореаль | Способ окрашивания кератиновых волокон с применением катионных стириловых дисульфидных красителей и композиция, содержащая указанные красители |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0512209A (pt) | 2008-02-19 |
| ATE538135T1 (de) | 2012-01-15 |
| CN1968963A (zh) | 2007-05-23 |
| JP2008504237A (ja) | 2008-02-14 |
| PL1765863T3 (pl) | 2012-05-31 |
| EP1765863B1 (en) | 2011-12-21 |
| US7897142B2 (en) | 2011-03-01 |
| ES2376557T3 (es) | 2012-03-14 |
| US20080095715A1 (en) | 2008-04-24 |
| RU2006144279A (ru) | 2008-07-27 |
| CN101001870A (zh) | 2007-07-18 |
| WO2005123768A1 (en) | 2005-12-29 |
| EP1765863A1 (en) | 2007-03-28 |
| JP5280683B2 (ja) | 2013-09-04 |
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