ATE538135T1 - Verbindungen auf peptidbasis - Google Patents

Verbindungen auf peptidbasis

Info

Publication number
ATE538135T1
ATE538135T1 AT05752383T AT05752383T ATE538135T1 AT E538135 T1 ATE538135 T1 AT E538135T1 AT 05752383 T AT05752383 T AT 05752383T AT 05752383 T AT05752383 T AT 05752383T AT E538135 T1 ATE538135 T1 AT E538135T1
Authority
AT
Austria
Prior art keywords
peptide
based compounds
angiogenesis
optical imaging
relates
Prior art date
Application number
AT05752383T
Other languages
German (de)
English (en)
Inventor
Alan Cuthbertson
Robert Nairne
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE538135T1 publication Critical patent/ATE538135T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056Peptides, proteins, polyamino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032Methine dyes, e.g. cyanine dyes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • C07K5/0817Tripeptides with the first amino acid being basic the first amino acid being Arg
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126Tetrapeptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05752383T 2004-06-16 2005-06-15 Verbindungen auf peptidbasis ATE538135T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20042523 2004-06-16
PCT/NO2005/000210 WO2005123768A1 (en) 2004-06-16 2005-06-15 Peptide-based compounds

Publications (1)

Publication Number Publication Date
ATE538135T1 true ATE538135T1 (de) 2012-01-15

Family

ID=34979156

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05752383T ATE538135T1 (de) 2004-06-16 2005-06-15 Verbindungen auf peptidbasis

Country Status (10)

Country Link
US (1) US7897142B2 (enExample)
EP (1) EP1765863B1 (enExample)
JP (1) JP5280683B2 (enExample)
CN (2) CN1968963A (enExample)
AT (1) ATE538135T1 (enExample)
BR (1) BRPI0512209A (enExample)
ES (1) ES2376557T3 (enExample)
PL (1) PL1765863T3 (enExample)
RU (1) RU2393167C2 (enExample)
WO (1) WO2005123768A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2719088T3 (es) * 2001-07-10 2019-07-08 Ge Healthcare Ltd Compuestos con base peptídica para localizar receptores de integrina
BRPI0518328A2 (pt) * 2004-11-22 2008-11-11 Ge Healthcare As agente de contraste, composiÇço farmacÊutica, uso de um agente de contraste, mÉtodo para gerar imagens realÇadas de um corpo animal ou humano, e, kit para a preparaÇço de um composiÇço radiofarmacÊutica
ITMI20050328A1 (it) 2005-03-03 2006-09-04 Univ Degli Studi Milano Composti peptidomimetrici e preparazione di derivati biologicamente attivi
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
EP3673922A1 (en) 2008-03-14 2020-07-01 VisEn Medical, Inc. Integrin targeting agents and methods of using same
US20100291706A1 (en) * 2009-05-15 2010-11-18 Millipore Corporation Dye conjugates and methods of use
EP2314597B1 (en) * 2009-10-21 2012-11-28 Cyanagen Srl Kit and method for the labelling of biomolecules
CN103052690A (zh) 2010-06-29 2013-04-17 通用电气医疗集团股份有限公司 染料组合物和染料合成
GB201010878D0 (en) 2010-06-29 2010-08-11 Ge Healthcare As Dye compositiion and dye syntheses
US9592307B2 (en) 2012-07-20 2017-03-14 Canon Kabushiki Kaisha Compound and photoacoustic imaging contrast medium containing the compound
WO2014055253A1 (en) * 2012-10-04 2014-04-10 The General Hospital Corporation Methods of synthesizing and using peg-like fluorochromes
WO2015059368A1 (fr) * 2013-09-02 2015-04-30 L'oreal Procede de coloration des fibres keratiniques a partir de colorants cationiques styryles disulfures, et composition comprenant lesdits colorants
CN107022350A (zh) * 2017-04-20 2017-08-08 深圳大学 一种荧光造影材料及其制备方法与应用
CN107739528A (zh) * 2017-09-30 2018-02-27 武汉工程大学 一种五肽改性菁染料化合物及其制备方法和应用
IL287989B2 (en) 2019-05-13 2025-07-01 Bracco Imaging Spa Modified cyanine dyes and their conjugates
EP4137502A4 (en) * 2020-03-30 2024-02-28 Ichimaru Pharcos Co., Ltd. Vipr2 antagonist peptide
EP4267971A4 (en) 2021-04-07 2024-08-07 Becton, Dickinson and Company Water-soluble fluorescent polymeric dyes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4445065A1 (de) * 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
ATE298763T1 (de) * 2000-04-12 2005-07-15 Amersham Health As Integrinbindende peptidderivate
ES2719088T3 (es) * 2001-07-10 2019-07-08 Ge Healthcare Ltd Compuestos con base peptídica para localizar receptores de integrina
NO20033115D0 (no) 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser

Also Published As

Publication number Publication date
JP5280683B2 (ja) 2013-09-04
EP1765863A1 (en) 2007-03-28
CN1968963A (zh) 2007-05-23
BRPI0512209A (pt) 2008-02-19
US7897142B2 (en) 2011-03-01
EP1765863B1 (en) 2011-12-21
RU2006144279A (ru) 2008-07-27
WO2005123768A1 (en) 2005-12-29
ES2376557T3 (es) 2012-03-14
JP2008504237A (ja) 2008-02-14
RU2393167C2 (ru) 2010-06-27
CN101001870A (zh) 2007-07-18
PL1765863T3 (pl) 2012-05-31
US20080095715A1 (en) 2008-04-24

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