RU2388764C2 - Способ получения смесей полипептидов с использованием очищенной бромистоводородной кислоты - Google Patents

Способ получения смесей полипептидов с использованием очищенной бромистоводородной кислоты Download PDF

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Publication number
RU2388764C2
RU2388764C2 RU2007112956/04A RU2007112956A RU2388764C2 RU 2388764 C2 RU2388764 C2 RU 2388764C2 RU 2007112956/04 A RU2007112956/04 A RU 2007112956/04A RU 2007112956 A RU2007112956 A RU 2007112956A RU 2388764 C2 RU2388764 C2 RU 2388764C2
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Russia
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solution
acetic acid
glatiramer acetate
hydrobromic acid
trifluoroacetyl
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RU2007112956/04A
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English (en)
Russian (ru)
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RU2007112956A (ru
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Бен-Зион ДОЛИТЦКИ (IL)
Бен-Зион ДОЛИТЦКИ
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Тева Фармасьютикал Индастриз, Лтд.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2007112956/04A 2004-09-09 2005-09-09 Способ получения смесей полипептидов с использованием очищенной бромистоводородной кислоты RU2388764C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60884304P 2004-09-09 2004-09-09
US60/608,843 2004-09-09

Publications (2)

Publication Number Publication Date
RU2007112956A RU2007112956A (ru) 2008-10-20
RU2388764C2 true RU2388764C2 (ru) 2010-05-10

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RU2007112956/04A RU2388764C2 (ru) 2004-09-09 2005-09-09 Способ получения смесей полипептидов с использованием очищенной бромистоводородной кислоты

Country Status (27)

Country Link
US (2) US7495072B2 (OSRAM)
EP (3) EP1799703B1 (OSRAM)
JP (1) JP5149008B2 (OSRAM)
KR (1) KR101317131B1 (OSRAM)
CN (1) CN101166754B (OSRAM)
AT (2) ATE536363T1 (OSRAM)
AU (1) AU2005282249B2 (OSRAM)
BR (1) BRPI0515033B1 (OSRAM)
CA (1) CA2579656C (OSRAM)
CY (1) CY1110280T1 (OSRAM)
DE (1) DE602005018800D1 (OSRAM)
DK (3) DK1799703T3 (OSRAM)
ES (3) ES2451006T3 (OSRAM)
HR (3) HRP20100164T1 (OSRAM)
IL (2) IL181596A (OSRAM)
IS (1) IS8622A (OSRAM)
MX (1) MX2007002760A (OSRAM)
NO (1) NO20071632L (OSRAM)
NZ (1) NZ554018A (OSRAM)
PL (3) PL2361924T3 (OSRAM)
PT (3) PT1799703E (OSRAM)
RS (3) RS53248B (OSRAM)
RU (1) RU2388764C2 (OSRAM)
SI (3) SI2361924T1 (OSRAM)
UA (1) UA91029C2 (OSRAM)
WO (1) WO2006029393A2 (OSRAM)
ZA (1) ZA200702591B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2604521C2 (ru) * 2011-02-14 2016-12-10 Юсв Прайвит Лимитед Сополимер-1, способы его получения и аналитические методы

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WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
DE60237170D1 (de) * 2001-12-04 2010-09-09 Teva Pharma Verfahren zur messung der wirkstärke von glatirameracetat
EP1778286A4 (en) * 2004-03-03 2009-04-08 Teva Pharma COMBINATION THERAPY WITH ACETATE OF GLATIRAMER AND RILUZOLE
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US8324641B2 (en) * 2007-06-29 2012-12-04 Ledengin, Inc. Matrix material including an embedded dispersion of beads for a light-emitting device
ES2331015T3 (es) * 2004-10-29 2009-12-18 Sandoz Ag Proceso para la preparacion de un glatiramero.
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US8859489B2 (en) * 2009-04-03 2014-10-14 Momenta Pharmaceuticals, Inc. Water-mediated control of depolymerization step of glatiramer acetate synthesis
UA103699C2 (ru) 2009-08-20 2013-11-11 Еда Рисёрч Энд Девелопмент Ко., Лтд. Терапия глатирамера ацетатом с низкой частотой
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EA025780B1 (ru) 2010-10-11 2017-01-30 Тева Фармасьютикал Индастриз Лтд. Цитокиновые биомаркеры в качестве биомаркеров, прогнозирующих клинический ответ на глатирамер ацетат
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JP5701103B2 (ja) * 2011-03-02 2015-04-15 昭和シェル石油株式会社 潤滑油のための消泡剤組成物及びそれを用いた消泡方法
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US20190202984A1 (en) * 2018-01-03 2019-07-04 Kinbio Ltd. Process of preparing glatiramer acetate

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SI2361924T1 (sl) 2014-04-30
MX2007002760A (es) 2007-05-18
BRPI0515033A8 (pt) 2019-01-22
RS53248B (sr) 2014-08-29
ES2451006T3 (es) 2014-03-26
ES2338138T3 (es) 2010-05-04
PT2177528E (pt) 2012-03-19
HRP20100164T1 (hr) 2010-07-31
EP2361924B1 (en) 2013-12-11
IL181596A0 (en) 2007-07-04
DK2361924T3 (en) 2014-03-10
HRP20120209T1 (hr) 2012-06-30
SI2177528T1 (sl) 2012-04-30
JP2008512494A (ja) 2008-04-24
DK2177528T3 (da) 2012-03-26
JP5149008B2 (ja) 2013-02-20
EP2361924A1 (en) 2011-08-31
UA91029C2 (uk) 2010-06-25
DE602005018800D1 (de) 2010-02-25
KR101317131B1 (ko) 2013-10-10
RS51257B (sr) 2010-12-31
IL181596A (en) 2015-10-29
NO20071632L (no) 2007-06-05
BRPI0515033B1 (pt) 2021-05-25
IL241702A0 (en) 2015-11-30
SI1799703T1 (sl) 2010-04-30
WO2006029393A2 (en) 2006-03-16
EP1799703A2 (en) 2007-06-27
EP1799703B1 (en) 2010-01-06
CY1110280T1 (el) 2015-01-14
PT1799703E (pt) 2010-03-04
WO2006029393A3 (en) 2007-12-13
AU2005282249B2 (en) 2012-08-02
ZA200702591B (en) 2009-03-25
BRPI0515033A (pt) 2008-07-01
HRP20140216T1 (hr) 2014-06-06
US20060052586A1 (en) 2006-03-09
US7495072B2 (en) 2009-02-24
NZ554018A (en) 2009-06-26
EP2177528A1 (en) 2010-04-21
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PT2361924E (pt) 2014-03-13
ATE454396T1 (de) 2010-01-15
ES2382298T3 (es) 2012-06-07
KR20070059137A (ko) 2007-06-11
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AU2005282249A1 (en) 2006-03-16
CN101166754B (zh) 2014-04-23
RS52265B (sr) 2012-10-31
HK1140775A1 (en) 2010-10-22
ATE536363T1 (de) 2011-12-15
DK1799703T3 (da) 2010-04-19
RU2007112956A (ru) 2008-10-20
HK1156637A1 (en) 2012-06-15
CN101166754A (zh) 2008-04-23
CA2579656C (en) 2014-11-04
PL1799703T3 (pl) 2010-06-30
PL2177528T3 (pl) 2012-09-28
IS8622A (is) 2007-03-16
EP1799703A4 (en) 2008-09-03
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CA2579656A1 (en) 2006-03-16
HK1100780A1 (en) 2007-09-28

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