PL2177528T3 - Sposób wytwarzania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowego - Google Patents
Sposób wytwarzania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowegoInfo
- Publication number
- PL2177528T3 PL2177528T3 PL10150124T PL10150124T PL2177528T3 PL 2177528 T3 PL2177528 T3 PL 2177528T3 PL 10150124 T PL10150124 T PL 10150124T PL 10150124 T PL10150124 T PL 10150124T PL 2177528 T3 PL2177528 T3 PL 2177528T3
- Authority
- PL
- Poland
- Prior art keywords
- mixtures
- preparation
- hydrobromic acid
- glatiramer acetate
- trifluoroacetyl glatiramer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Rehabilitation Therapy (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60884304P | 2004-09-09 | 2004-09-09 | |
| EP10150124A EP2177528B1 (en) | 2004-09-09 | 2005-09-09 | Process for the preparation of mixtures of trifluoroacetyl glatiramer acetate using purified hydrobromic acid |
| EP05791236A EP1799703B1 (en) | 2004-09-09 | 2005-09-09 | Process for preparation of mixtures of polypeptides using purified hydrobromic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2177528T3 true PL2177528T3 (pl) | 2012-09-28 |
Family
ID=36037047
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10194363T PL2361924T3 (pl) | 2004-09-09 | 2005-09-09 | Proces przygotowania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowego |
| PL05791236T PL1799703T3 (pl) | 2004-09-09 | 2005-09-09 | Sposób wytwarzania mieszaniny polipeptydów stosując oczyszczony kwas bromowodorowy |
| PL10150124T PL2177528T3 (pl) | 2004-09-09 | 2005-09-09 | Sposób wytwarzania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowego |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10194363T PL2361924T3 (pl) | 2004-09-09 | 2005-09-09 | Proces przygotowania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowego |
| PL05791236T PL1799703T3 (pl) | 2004-09-09 | 2005-09-09 | Sposób wytwarzania mieszaniny polipeptydów stosując oczyszczony kwas bromowodorowy |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US7495072B2 (pl) |
| EP (3) | EP1799703B1 (pl) |
| JP (1) | JP5149008B2 (pl) |
| KR (1) | KR101317131B1 (pl) |
| CN (1) | CN101166754B (pl) |
| AT (2) | ATE454396T1 (pl) |
| AU (1) | AU2005282249B2 (pl) |
| BR (1) | BRPI0515033B1 (pl) |
| CA (1) | CA2579656C (pl) |
| CY (1) | CY1110280T1 (pl) |
| DE (1) | DE602005018800D1 (pl) |
| DK (3) | DK1799703T3 (pl) |
| ES (3) | ES2338138T3 (pl) |
| HR (3) | HRP20100164T1 (pl) |
| IL (2) | IL181596A (pl) |
| IS (1) | IS8622A (pl) |
| MX (1) | MX2007002760A (pl) |
| NO (1) | NO20071632L (pl) |
| NZ (1) | NZ554018A (pl) |
| PL (3) | PL2361924T3 (pl) |
| PT (3) | PT2361924E (pl) |
| RS (3) | RS53248B (pl) |
| RU (1) | RU2388764C2 (pl) |
| SI (3) | SI1799703T1 (pl) |
| UA (1) | UA91029C2 (pl) |
| WO (1) | WO2006029393A2 (pl) |
| ZA (1) | ZA200702591B (pl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL141021A0 (en) | 1998-07-23 | 2002-02-10 | Yeda Res & Dev | Treatment of autoimmune conditions with copolymer 1 and related copolymers |
| ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| US6800287B2 (en) | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
| WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
| NZ533327A (en) * | 2001-12-04 | 2006-11-30 | Teva Pharma | Processes for the measurement of the potency of glatiramer acetate |
| AU2005218625A1 (en) * | 2004-03-03 | 2005-09-15 | Teva Pharmaceutical Industries, Ltd. | Combination therapy with glatiramer acetate and riluzole |
| ES2572811T3 (es) * | 2004-09-09 | 2016-06-02 | Yeda Research And Development Co., Ltd. | Mezclas de polipéptidos, composiciones que las contienen y procedimientos para obtener los mismos, y usos de los mismos |
| PT2361924E (pt) | 2004-09-09 | 2014-03-13 | Teva Pharma | Processo para a preparação de misturas de acetato de glatirâmero trifluoroacetiílico utilizando ácido bromídrico purificado |
| AU2005302500B2 (en) * | 2004-10-29 | 2008-11-27 | Sandoz Ag | Processes for preparing glatiramer |
| US8324641B2 (en) * | 2007-06-29 | 2012-12-04 | Ledengin, Inc. | Matrix material including an embedded dispersion of beads for a light-emitting device |
| EP1838326A4 (en) * | 2005-02-02 | 2009-09-30 | Teva Pharma | PROCESS FOR PREPARING POLYPEPTIDE MIXTURES BY HYDROGENOLYSIS |
| PT1848415E (pt) * | 2005-02-17 | 2013-06-27 | Teva Pharma | Terapia de combinação com acetato de glatirâmero e rasagilina para o tratamento da esclerose múltipla |
| WO2006116602A2 (en) * | 2005-04-25 | 2006-11-02 | Yeda Research And Development Company | Markers associated with the therapeutic efficacy of glatiramer acetate |
| US20090035816A1 (en) * | 2007-08-02 | 2009-02-05 | Scinopharm Taiwan Ltd. | Process for the preparation of a polypeptide |
| EA201070656A1 (ru) * | 2007-11-28 | 2010-12-30 | Тева Фармасьютикал Индастриз, Лтд. | Способ задержки начала проявления клинически определенного рассеянного склероза |
| ES2449865T5 (es) | 2008-04-16 | 2022-11-18 | Momenta Pharmaceuticals Inc | Análisis de composiciones de copolímeros de aminoácidos |
| CA2733500A1 (en) * | 2008-08-07 | 2010-02-11 | Scinopharm Taiwan, Ltd. | Synthesis of glatiramer acetate |
| WO2010017075A1 (en) * | 2008-08-07 | 2010-02-11 | Sigma-Aldrich Co. | Preparation of low molecular weight polylysine and polyornithine in high yield |
| WO2010115175A1 (en) | 2009-04-03 | 2010-10-07 | Momenta Pharmaceticals, Inc. | Control of copolymer compositions |
| EA019998B9 (ru) | 2009-08-20 | 2016-01-29 | Йеда Рисерч Энд Дивелопмент Ко. Лтд. | Терапия глатирамером ацетатом с низкой кратностью |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| KR20130062936A (ko) * | 2010-04-27 | 2013-06-13 | 닥터 레디스 레보러터리즈 리미티드 | 폴리펩티드 및 그의 염의 제조 |
| PL2627669T3 (pl) | 2010-10-11 | 2017-02-28 | Teva Pharmaceutical Industries Ltd. | Biomarkery cytokinowe jako biomarkery prognostyczne odpowiedzi klinicznej na octan glatirameru |
| US8788046B2 (en) | 2010-11-11 | 2014-07-22 | Spr Therapeutics, Llc | Systems and methods for the treatment of pain through neural fiber stimulation |
| RU2604521C2 (ru) * | 2011-02-14 | 2016-12-10 | Юсв Прайвит Лимитед | Сополимер-1, способы его получения и аналитические методы |
| JP5701103B2 (ja) * | 2011-03-02 | 2015-04-15 | 昭和シェル石油株式会社 | 潤滑油のための消泡剤組成物及びそれを用いた消泡方法 |
| EP2699317B1 (en) | 2011-04-21 | 2016-08-10 | Mapi Pharma Limited | Random pentapolymer for treatment of autoimmune diseases |
| WO2013009885A2 (en) | 2011-07-11 | 2013-01-17 | Momenta Pharmaceuticals, Inc. | Evaluation of copolymer diethylamide |
| WO2013009864A1 (en) | 2011-07-11 | 2013-01-17 | Momenta Pharmaceuticals, Inc. | Structure assessment of heterogeneous polypeptide mixtures |
| US8575198B1 (en) | 2011-09-07 | 2013-11-05 | Momenta Pharmaceuticals, Inc. | In-process control for the manufacture of glatiramer acetate |
| EP2765857A4 (en) | 2011-10-10 | 2015-12-09 | Teva Pharma | SIMPLE NUCLEOTIDE POLYMORPHISMS USEFUL FOR PREDICTING CLINICAL RESPONSE TO GLATIRAMERATE ACETATE |
| CN102717992A (zh) * | 2012-05-30 | 2012-10-10 | 苏州市旭洋工业搪瓷厂 | 一种搪玻璃溴素贮罐 |
| CN102718963B (zh) * | 2012-06-19 | 2014-10-15 | 深圳翰宇药业股份有限公司 | 聚合物多肽的制备方法 |
| HK1213830A1 (zh) | 2012-10-10 | 2016-07-15 | Teva Pharmaceutical Industries Ltd. | 用於预测醋酸格拉替雷临床反应的生物标志物 |
| UY35790A (es) | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| WO2015066515A1 (en) | 2013-11-01 | 2015-05-07 | Receptos, Inc. | Selective sphingosine 1 phosphate receptor modulators and combination therapy therewith |
| CN104844697B (zh) | 2014-09-26 | 2018-10-23 | 深圳翰宇药业股份有限公司 | 醋酸格拉替雷的制备方法 |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| AU2017319728B2 (en) | 2016-08-31 | 2024-09-05 | Mapi Pharma Ltd | Depot systems comprising glatiramer acetate |
| MX2019010174A (es) | 2017-03-26 | 2019-10-15 | Mapi Pharma Ltd | Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple. |
| US20190202984A1 (en) * | 2018-01-03 | 2019-07-04 | Kinbio Ltd. | Process of preparing glatiramer acetate |
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| IL141021A0 (en) | 1998-07-23 | 2002-02-10 | Yeda Res & Dev | Treatment of autoimmune conditions with copolymer 1 and related copolymers |
| ES2527760T3 (es) | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| US6800287B2 (en) | 1998-09-25 | 2004-10-05 | Yeda Research And Development Co., Ltd. | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
| US6514938B1 (en) | 1998-09-25 | 2003-02-04 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
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| EP1261361B1 (en) | 2000-02-18 | 2006-06-14 | Yeda Research And Development Company, Ltd. | Oral, nasal and pulmonary dosage formulations of copolymer 1 (glatiramer acetate) |
| ZA200206457B (en) | 2000-02-18 | 2003-08-13 | Yeda Res & Dev | Oral, nasal and pulmonary dosage formulations of copolymer 1. |
| US20020077278A1 (en) | 2000-06-05 | 2002-06-20 | Yong V. Wee | Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders |
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| WO2002076503A1 (en) | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
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| EP1838326A4 (en) | 2005-02-02 | 2009-09-30 | Teva Pharma | PROCESS FOR PREPARING POLYPEPTIDE MIXTURES BY HYDROGENOLYSIS |
| WO2006116602A2 (en) * | 2005-04-25 | 2006-11-02 | Yeda Research And Development Company | Markers associated with the therapeutic efficacy of glatiramer acetate |
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-
2005
- 2005-09-09 PT PT101943637T patent/PT2361924E/pt unknown
- 2005-09-09 CN CN200580033851.5A patent/CN101166754B/zh not_active Expired - Lifetime
- 2005-09-09 ZA ZA200702591A patent/ZA200702591B/xx unknown
- 2005-09-09 NZ NZ554018A patent/NZ554018A/en not_active IP Right Cessation
- 2005-09-09 KR KR1020077007738A patent/KR101317131B1/ko not_active Expired - Lifetime
- 2005-09-09 WO PCT/US2005/032395 patent/WO2006029393A2/en not_active Ceased
- 2005-09-09 JP JP2007531423A patent/JP5149008B2/ja not_active Expired - Fee Related
- 2005-09-09 PL PL10194363T patent/PL2361924T3/pl unknown
- 2005-09-09 AU AU2005282249A patent/AU2005282249B2/en not_active Expired
- 2005-09-09 SI SI200530934T patent/SI1799703T1/sl unknown
- 2005-09-09 RU RU2007112956/04A patent/RU2388764C2/ru active
- 2005-09-09 PL PL05791236T patent/PL1799703T3/pl unknown
- 2005-09-09 EP EP05791236A patent/EP1799703B1/en not_active Revoked
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- 2005-09-09 ES ES05791236T patent/ES2338138T3/es not_active Expired - Lifetime
- 2005-09-09 HR HR20100164T patent/HRP20100164T1/hr unknown
- 2005-09-09 DK DK05791236.2T patent/DK1799703T3/da active
- 2005-09-09 SI SI200531830T patent/SI2361924T1/sl unknown
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- 2005-09-09 AT AT05791236T patent/ATE454396T1/de active
- 2005-09-09 PT PT05791236T patent/PT1799703E/pt unknown
- 2005-09-09 EP EP10150124A patent/EP2177528B1/en not_active Revoked
- 2005-09-09 DK DK10150124.5T patent/DK2177528T3/da active
- 2005-09-09 EP EP10194363.7A patent/EP2361924B1/en not_active Revoked
- 2005-09-09 PT PT10150124T patent/PT2177528E/pt unknown
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- 2005-09-09 DE DE602005018800T patent/DE602005018800D1/de not_active Expired - Lifetime
- 2005-09-09 ES ES10150124T patent/ES2382298T3/es not_active Expired - Lifetime
- 2005-09-09 SI SI200531482T patent/SI2177528T1/sl unknown
- 2005-09-09 AT AT10150124T patent/ATE536363T1/de active
- 2005-09-09 ES ES10194363.7T patent/ES2451006T3/es not_active Expired - Lifetime
- 2005-09-09 PL PL10150124T patent/PL2177528T3/pl unknown
- 2005-09-09 MX MX2007002760A patent/MX2007002760A/es active IP Right Grant
- 2005-09-09 BR BRPI0515033-7A patent/BRPI0515033B1/pt not_active IP Right Cessation
- 2005-09-09 DK DK10194363.7T patent/DK2361924T3/en active
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2006
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2010
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2012
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2014
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2015
- 2015-09-17 IL IL241702A patent/IL241702A0/en unknown
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