MXPA04000597A - Peptidos novedosos de la proteina g del virus sincicial respiratorio (rsv), y su uso en una vacuna. - Google Patents

Peptidos novedosos de la proteina g del virus sincicial respiratorio (rsv), y su uso en una vacuna.

Info

Publication number
MXPA04000597A
MXPA04000597A MXPA04000597A MXPA04000597A MXPA04000597A MX PA04000597 A MXPA04000597 A MX PA04000597A MX PA04000597 A MXPA04000597 A MX PA04000597A MX PA04000597 A MXPA04000597 A MX PA04000597A MX PA04000597 A MXPA04000597 A MX PA04000597A
Authority
MX
Mexico
Prior art keywords
protein
rsv
vaccine
respiratory syncytial
syncytial virus
Prior art date
Application number
MXPA04000597A
Other languages
English (en)
Inventor
Nguyen Ngoc Thien
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of MXPA04000597A publication Critical patent/MXPA04000597A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

La invencion se refiere a peptidos inmunogenos novedosos derivados de la proteina G del RSV del subgrupo A o B, que comprenden por lo menos: un primer peptido derivado de la proteina G del RSV del subgrupo A o B que incluye por lo menos en la posicion 173, 176, 182 y 186 una cisteina, y cuyo extremo C-terminal incluye cuando mucho el aminoacido en la posicion 192; y un segundo peptido derivado de la proteina G del RSV del subgrupo A o B, dicho segundo peptido estando localizado hacia el extremo 3° de dicha primera proteina, de modo que el peptido inmunogeno producido tiene un enlace disulfuro que une los residuos 173 y 186, y un segundo enlace disulfuro que une los residuos 176 y 182.
MXPA04000597A 2001-07-20 2002-07-19 Peptidos novedosos de la proteina g del virus sincicial respiratorio (rsv), y su uso en una vacuna. MXPA04000597A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0109731A FR2827605B1 (fr) 2001-07-20 2001-07-20 Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin
PCT/FR2002/002599 WO2003010317A1 (fr) 2001-07-20 2002-07-19 Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin

Publications (1)

Publication Number Publication Date
MXPA04000597A true MXPA04000597A (es) 2004-04-20

Family

ID=8865750

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04000597A MXPA04000597A (es) 2001-07-20 2002-07-19 Peptidos novedosos de la proteina g del virus sincicial respiratorio (rsv), y su uso en una vacuna.

Country Status (16)

Country Link
US (3) US7309494B2 (es)
EP (1) EP1409692B1 (es)
JP (1) JP4310184B2 (es)
CN (1) CN1556857A (es)
AT (1) ATE408696T1 (es)
AU (1) AU2002336148B8 (es)
BR (1) BR0211296A (es)
CA (1) CA2455360A1 (es)
DE (1) DE60228971D1 (es)
DK (1) DK1409692T3 (es)
ES (1) ES2314102T3 (es)
FR (1) FR2827605B1 (es)
MX (1) MXPA04000597A (es)
PT (1) PT1409692E (es)
WO (1) WO2003010317A1 (es)
ZA (1) ZA200400916B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1334119T4 (en) 2000-10-18 2019-03-18 The Government Of The Us Secretary Department Of Health And Human Services Compositions and Methods for Modulating RSV Infection and Immunity
EP1768993A4 (en) * 2004-06-16 2008-07-23 Univ Johns Hopkins CYSTEINE-RICH REGION OF SYNCYTIAL RESPIRATORY VIRUS AND METHODS OF USE THEREOF
EP1972348A1 (en) * 2007-03-14 2008-09-24 Pierre Fabre Medicament Novel vaccine composition for the treatment of respiratory infectious diseases
EP2331127A2 (en) 2008-09-18 2011-06-15 Novartis AG Vaccine adjuvant combinations
CN102711818B (zh) 2009-08-04 2014-09-24 美利坚合众国政府疾病控制和预防中心,健康和公共事业部 抗rsv免疫原和免疫方法
AU2010288239B2 (en) 2009-08-27 2014-01-16 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
MX2012002723A (es) 2009-09-02 2012-04-11 Novartis Ag Composiciones inmunogenicas que incluyen moduladores de la actividad de receptores tipo toll.
AU2010339715B2 (en) * 2009-12-21 2015-07-09 Cornell University Novel pneumovirus compositions and methods for using the same
ES2458355T3 (es) 2010-09-01 2014-05-05 Novartis Ag Adsorción de inmunopotenciadores sobre sales metálicas insolubles
WO2012082914A1 (en) 2010-12-14 2012-06-21 Novartis Ag Flow cytometry analysis of materials adsorbed to metal salts
RU2013144207A (ru) 2011-03-02 2015-04-10 Новартис Аг Комбинированные вакцины с пониженными дозами антигена и/или адъюванта
KR20140027211A (ko) 2011-04-04 2014-03-06 유니버시티 오브 아이오와 리써치 파운데이션 백신 면역원성의 개선 방법
ES2395677B1 (es) * 2011-07-29 2013-12-26 Instituto De Salud Carlos Iii Proteína F del VRSH en conformación pre-fusión estabilizada y anticuerpos neutralizantes específicos frente a la misma.
CN103239734B (zh) * 2012-02-10 2016-02-24 北京艾棣维欣生物技术有限公司 用于预防和/或治疗呼吸道合胞病毒感染的疫苗
WO2013131983A1 (en) 2012-03-07 2013-09-12 Novartis Ag Adjuvanted formulations of streptococcus pneumoniae antigens
DK2822947T3 (en) 2012-03-07 2016-09-19 Glaxosmithkline Biologicals Sa ARGINAL SALTS OF A TLR-7 AGONIST
RU2014140521A (ru) 2012-03-08 2016-04-27 Новартис Аг Адъювантные составы бустерных вакцин
JP6523955B2 (ja) 2012-08-01 2019-06-05 バヴァリアン・ノルディック・アクティーゼルスカブ 組換え改変ワクシニアウイルスアンカラ（ｍｖａ）ｒｓウイルス（ｒｓｖ）ワクチン
CN105085684B (zh) * 2014-05-14 2020-04-17 上海亨臻实业有限公司 Pcsk9靶向重组疫苗设计及其应用
WO2016160166A1 (en) * 2015-03-30 2016-10-06 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Immunogenic rsv polypeptides
CA3052708A1 (en) 2016-02-16 2017-08-24 The University Of Queensland Novel alpha conotoxin peptides
CN109232737A (zh) * 2016-03-01 2019-01-18 苏州博泰神州生物技术有限公司 一种针对rsv粘附g蛋白表面抗原的全人源单克隆抗体
CN113543803A (zh) 2019-02-28 2021-10-22 Km生物医药股份公司 Rsv f/g嵌合疫苗
US11360877B2 (en) * 2020-09-14 2022-06-14 International Business Machines Corporation Forming microservices from monolithic applications

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01501357A (ja) 1986-01-14 1989-05-18 ユニバ−シテイ・オブ・ノ−ス・カロライナ ヒト呼吸器系ウイルス用ワクチン
US5223254A (en) 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
AUPO026596A0 (en) 1996-06-05 1996-06-27 Biomolecular Research Institute Limited Viral peptide
FR2766192B1 (fr) 1997-07-17 2001-07-13 Pf Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
FR2776521B1 (fr) 1998-03-27 2000-12-15 Pf Medicament Utilisation de conjugues p40 actifs par voie nasale
FR2798857B1 (fr) * 1999-09-23 2003-06-06 Pf Medicament Utilisation d'une proteine de membrane ompa d'enterobacterie associee a un peptide immunogene du vrs pour la preparation de vaccins administrables par voie nasale

Also Published As

Publication number Publication date
ATE408696T1 (de) 2008-10-15
FR2827605A1 (fr) 2003-01-24
EP1409692B1 (fr) 2008-09-17
JP2005511010A (ja) 2005-04-28
ES2314102T3 (es) 2009-03-16
EP1409692A1 (fr) 2004-04-21
WO2003010317A1 (fr) 2003-02-06
JP4310184B2 (ja) 2009-08-05
FR2827605B1 (fr) 2004-07-16
US20090036367A1 (en) 2009-02-05
BR0211296A (pt) 2004-09-14
CA2455360A1 (fr) 2003-02-06
PT1409692E (pt) 2008-12-26
DK1409692T3 (da) 2009-02-02
US7524627B2 (en) 2009-04-28
US7309494B2 (en) 2007-12-18
DE60228971D1 (de) 2008-10-30
CN1556857A (zh) 2004-12-22
US20040175395A1 (en) 2004-09-09
US20090181042A1 (en) 2009-07-16
AU2002336148B8 (en) 2008-06-19
ZA200400916B (en) 2004-08-25
AU2002336148B2 (en) 2007-12-13

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