BR0212287A - Proteìna de ligação caspase-8, sua preparação e uso - Google Patents
Proteìna de ligação caspase-8, sua preparação e usoInfo
- Publication number
- BR0212287A BR0212287A BR0212287-1A BR0212287A BR0212287A BR 0212287 A BR0212287 A BR 0212287A BR 0212287 A BR0212287 A BR 0212287A BR 0212287 A BR0212287 A BR 0212287A
- Authority
- BR
- Brazil
- Prior art keywords
- caspase
- preparation
- binding protein
- cari
- methods
- Prior art date
Links
- 102000004091 Caspase-8 Human genes 0.000 title abstract 3
- 108090000538 Caspase-8 Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
Abstract
"PROTEìNA DE LIGAçãO CASPASE-8, SUA PREPARAçãO E USO". A presente invenção refere-se a um polipeptídeo de interação da caspase-8 (Cari), métodos para sua preparação e seu uso.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14527801A IL145278A0 (en) | 2001-09-04 | 2001-09-04 | A caspase-8 binding protein, its preparation and use |
IL14625101A IL146251A0 (en) | 2001-09-04 | 2001-10-31 | A caspase-8 binding protein, its preparation and use |
IL14748702A IL147487A0 (en) | 2002-01-06 | 2002-01-06 | A caspase-8 binding protein, its preparation and use |
PCT/IL2002/000733 WO2003020759A2 (en) | 2001-09-04 | 2002-09-04 | A caspase- 8 binding protein, its preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0212287A true BR0212287A (pt) | 2004-09-14 |
Family
ID=27271952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0212287-1A BR0212287A (pt) | 2001-09-04 | 2002-09-04 | Proteìna de ligação caspase-8, sua preparação e uso |
Country Status (10)
Country | Link |
---|---|
US (2) | US7354736B2 (pt) |
EP (1) | EP1423422A2 (pt) |
JP (1) | JP2005501545A (pt) |
KR (1) | KR20040049845A (pt) |
CN (1) | CN1630664A (pt) |
BR (1) | BR0212287A (pt) |
CA (1) | CA2459136A1 (pt) |
EA (1) | EA009956B1 (pt) |
MX (1) | MXPA04002103A (pt) |
WO (1) | WO2003020759A2 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE478559T1 (de) | 2006-05-03 | 2010-09-15 | Univ California | Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde |
AU2007264672B2 (en) * | 2006-06-28 | 2013-03-14 | Hadasit Medical Research Services & Development Ltd | Caspase-8 and inflammation, infection and wound healing |
US8150192B2 (en) * | 2006-11-27 | 2012-04-03 | Merge Cad Inc. | System and method for feature score mapping and visualization of medical images |
US8778302B2 (en) * | 2007-03-09 | 2014-07-15 | The University Of British Columbia | Procaspase 8-mediated disease targeting |
KR101682730B1 (ko) | 2008-10-08 | 2016-12-05 | 캠브리지 엔터프라이즈 리미티드 | 다발경화증에 대한 2차 자가면역 질환의 진단 및 치료를 위한 방법 및 조성물 |
EP2855666B1 (en) | 2012-05-25 | 2019-12-04 | Cellectis | Use of pre t alpha or functional variant thereof for expanding tcr alpha deficient t cells |
AU2013312838B2 (en) * | 2012-09-04 | 2018-11-29 | Cellectis | Multi-chain chimeric antigen receptor and uses thereof |
RU2671510C1 (ru) * | 2016-06-29 | 2018-11-01 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ выделения белкового высокомолекулярного комплекса активации каспазы-2 человека |
WO2018068022A1 (en) | 2016-10-06 | 2018-04-12 | Poseida Therapeutics, Inc. | Inducible caspases and methods for use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2276085A1 (en) * | 1997-01-09 | 1998-07-16 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
IL132105A0 (en) * | 1998-12-24 | 2001-03-19 | Yeda Res & Dev | Caspase-8 interacting proteins |
US20040101927A9 (en) * | 2000-01-31 | 2004-05-27 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
-
2002
- 2002-09-04 WO PCT/IL2002/000733 patent/WO2003020759A2/en active Application Filing
- 2002-09-04 KR KR10-2004-7003218A patent/KR20040049845A/ko not_active Application Discontinuation
- 2002-09-04 EA EA200400392A patent/EA009956B1/ru not_active IP Right Cessation
- 2002-09-04 BR BR0212287-1A patent/BR0212287A/pt not_active IP Right Cessation
- 2002-09-04 CA CA002459136A patent/CA2459136A1/en not_active Abandoned
- 2002-09-04 JP JP2003525029A patent/JP2005501545A/ja active Pending
- 2002-09-04 US US10/488,614 patent/US7354736B2/en not_active Expired - Fee Related
- 2002-09-04 CN CNA02821966XA patent/CN1630664A/zh active Pending
- 2002-09-04 MX MXPA04002103A patent/MXPA04002103A/es not_active Application Discontinuation
- 2002-09-04 EP EP02758770A patent/EP1423422A2/en not_active Withdrawn
-
2008
- 2008-02-26 US US12/037,719 patent/US20080254028A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2005501545A (ja) | 2005-01-20 |
US20050048639A1 (en) | 2005-03-03 |
EP1423422A2 (en) | 2004-06-02 |
EA009956B1 (ru) | 2008-04-28 |
CN1630664A (zh) | 2005-06-22 |
US20080254028A1 (en) | 2008-10-16 |
EA200400392A1 (ru) | 2004-10-28 |
US7354736B2 (en) | 2008-04-08 |
KR20040049845A (ko) | 2004-06-12 |
WO2003020759A9 (en) | 2003-12-31 |
WO2003020759A2 (en) | 2003-03-13 |
MXPA04002103A (es) | 2004-06-07 |
WO2003020759A3 (en) | 2003-11-27 |
CA2459136A1 (en) | 2003-03-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUI DADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011. |