WO2001002429A3 - Angiopoietin-6 and uses thereof - Google Patents

Angiopoietin-6 and uses thereof Download PDF

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Publication number
WO2001002429A3
WO2001002429A3 PCT/EP2000/006002 EP0006002W WO0102429A3 WO 2001002429 A3 WO2001002429 A3 WO 2001002429A3 EP 0006002 W EP0006002 W EP 0006002W WO 0102429 A3 WO0102429 A3 WO 0102429A3
Authority
WO
WIPO (PCT)
Prior art keywords
provides
protein
ang
angiopoietin
antibody
Prior art date
Application number
PCT/EP2000/006002
Other languages
French (fr)
Other versions
WO2001002429A2 (en
Inventor
Gustav Hagen
Gabi Friedrich
Maresa Wick
Dmitri Zubov
Original Assignee
Bayer Ag
Gustav Hagen
Gabi Friedrich
Maresa Wick
Dmitri Zubov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Gustav Hagen, Gabi Friedrich, Maresa Wick, Dmitri Zubov filed Critical Bayer Ag
Priority to AU59793/00A priority Critical patent/AU5979300A/en
Publication of WO2001002429A2 publication Critical patent/WO2001002429A2/en
Publication of WO2001002429A3 publication Critical patent/WO2001002429A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention provides a nucleic acid molecule encoding human Angiopoietin-6 (Ang-6) protein. In addition the invention provides methods for producing recombinant human Ang-6 protein. The invention also provides an antibody which specifically binds human Ang-6 protein. The invention further provides for therapeutic compositions.
PCT/EP2000/006002 1999-07-02 2000-06-28 Angiopoietin-6 and uses thereof WO2001002429A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU59793/00A AU5979300A (en) 1999-07-02 2000-06-28 Angiopoietin-6 and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99113503.9 1999-07-02
EP99113503 1999-07-02

Publications (2)

Publication Number Publication Date
WO2001002429A2 WO2001002429A2 (en) 2001-01-11
WO2001002429A3 true WO2001002429A3 (en) 2001-03-15

Family

ID=8238584

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/006002 WO2001002429A2 (en) 1999-07-02 2000-06-28 Angiopoietin-6 and uses thereof

Country Status (2)

Country Link
AU (1) AU5979300A (en)
WO (1) WO2001002429A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1484401A1 (en) * 1999-07-20 2004-12-08 Curagen Corporation Secreted polypeptides and corresponding polynucleotides
US20050123925A1 (en) 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
ES2339789T3 (en) 2004-07-20 2010-05-25 Genentech, Inc. PROTEIN 4 INHIBITORS OF ANGIOPOYETINE TYPE, COMBINATIONS AND ITS USE.
US8604185B2 (en) 2004-07-20 2013-12-10 Genentech, Inc. Inhibitors of angiopoietin-like 4 protein, combinations, and their use
LT1781698T (en) 2004-07-20 2016-09-26 Genentech, Inc. Compositions and methods of using angiopoietin-like 4 protein

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015654A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie receptor tyrosine kinase ligand homologues
WO1999032515A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Angiopoietin homolog, dna encoding it, and method of making it
WO1999066041A1 (en) * 1998-06-16 1999-12-23 Human Genome Sciences, Inc. 94 human secreted proteins
WO1999067382A2 (en) * 1998-06-24 1999-12-29 Compugen Ltd. Angiopoietin-like growth factor sequences

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015654A2 (en) * 1997-09-19 1999-04-01 Genentech, Inc. Tie receptor tyrosine kinase ligand homologues
WO1999032515A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Angiopoietin homolog, dna encoding it, and method of making it
WO1999066041A1 (en) * 1998-06-16 1999-12-23 Human Genome Sciences, Inc. 94 human secreted proteins
WO1999067382A2 (en) * 1998-06-24 1999-12-29 Compugen Ltd. Angiopoietin-like growth factor sequences

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENEMBL 30 June 1999 (1999-06-30), KIM ET AL.: "Homo sapiens angiopoietein-related protein mRNA, complete cds", XP002154528 *
DATABASE GENEMBL 7 April 2000 (2000-04-07), KIM ET AL.: "Homo sapiens hepatic angiopoietin-related protein (ANGPTL2) mRNA, complete cds.", XP002154529 *
KIM ET AL.: "Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis", BIOCHEM. J., vol. 346, no. 3, 15 March 2000 (2000-03-15), pages 603 - 610, XP000971125 *

Also Published As

Publication number Publication date
WO2001002429A2 (en) 2001-01-11
AU5979300A (en) 2001-01-22

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