RU2357726C2 - Лечение и профилактика доброкачественной опухоли груди 4-гидрокситамоксифеном - Google Patents

Лечение и профилактика доброкачественной опухоли груди 4-гидрокситамоксифеном Download PDF

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Publication number
RU2357726C2
RU2357726C2 RU2006137280/15A RU2006137280A RU2357726C2 RU 2357726 C2 RU2357726 C2 RU 2357726C2 RU 2006137280/15 A RU2006137280/15 A RU 2006137280/15A RU 2006137280 A RU2006137280 A RU 2006137280A RU 2357726 C2 RU2357726 C2 RU 2357726C2
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Russia
Prior art keywords
hydroxy tamoxifen
named
weight
tamoxifen
composition
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RU2006137280/15A
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English (en)
Russian (ru)
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RU2006137280A (ru
Inventor
НЕСТУР Элизабет ЛЕ (FR)
НЕСТУР Элизабет ЛЕ
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Лаборатуар Безен Энтернасьональ
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Publication date
Priority claimed from EP04290761A external-priority patent/EP1579856A1/en
Priority claimed from US10/805,528 external-priority patent/US7507769B2/en
Application filed by Лаборатуар Безен Энтернасьональ filed Critical Лаборатуар Безен Энтернасьональ
Publication of RU2006137280A publication Critical patent/RU2006137280A/ru
Application granted granted Critical
Publication of RU2357726C2 publication Critical patent/RU2357726C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
RU2006137280/15A 2004-03-22 2005-03-10 Лечение и профилактика доброкачественной опухоли груди 4-гидрокситамоксифеном RU2357726C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/805,528 2004-03-22
EP04290761A EP1579856A1 (en) 2004-03-22 2004-03-22 Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP04290761.8 2004-03-22
US10/805,528 US7507769B2 (en) 2004-03-22 2004-03-22 Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen

Publications (2)

Publication Number Publication Date
RU2006137280A RU2006137280A (ru) 2008-04-27
RU2357726C2 true RU2357726C2 (ru) 2009-06-10

Family

ID=34961912

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006137280/15A RU2357726C2 (ru) 2004-03-22 2005-03-10 Лечение и профилактика доброкачественной опухоли груди 4-гидрокситамоксифеном

Country Status (16)

Country Link
EP (1) EP1748770B1 (https=)
JP (1) JP5072588B2 (https=)
CN (1) CN1946387B (https=)
AT (1) ATE391499T1 (https=)
AU (1) AU2005227072B2 (https=)
CA (1) CA2559748C (https=)
DE (1) DE602005005986T2 (https=)
DK (1) DK1748770T3 (https=)
ES (1) ES2306111T3 (https=)
MX (1) MXPA06010914A (https=)
NO (1) NO336767B1 (https=)
NZ (1) NZ549817A (https=)
PL (1) PL1748770T3 (https=)
PT (1) PT1748770E (https=)
RU (1) RU2357726C2 (https=)
WO (1) WO2005092309A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1799201B1 (en) * 2004-10-14 2008-11-26 Laboratoires Besins International 4-hydroxy tamoxifen gel formulations

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4919937A (en) * 1984-01-20 1990-04-24 Mauvais Jarvis Pierre Percutaneous administration of tamoxifen
US4973755A (en) * 1987-04-21 1990-11-27 Heumann Pharma Gmbh & Co. Stable solvent adducts of Z-1-(p-β-dimethylaminoethoxy-phenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene
RU2188000C1 (ru) * 2001-09-27 2002-08-27 Нестерук Владимир Викторович Лекарственное средство на основе тамоксифена
US20030087885A1 (en) * 2001-11-07 2003-05-08 Valerie Masini-Eteve Pharmaceutical composition in the form of a gel or a solution based on dihydrotestosterone, process for preparing it and uses thereof
RU2207844C2 (ru) * 1998-12-23 2003-07-10 Идеа Аг. УСОВЕРШЕНСТВОВАННЫЙ ПРЕПАРАТ ДЛЯ МЕСТНОГО НЕИНВАЗИВНОГО ПРИМЕНЕНИЯ in vivo

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515041A1 (fr) * 1981-10-26 1983-04-29 Besins Jean Medicament a base de progesterone pour le traitement des affections mammaires
DE4407742C1 (de) * 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
WO2004054557A2 (en) * 2002-12-18 2004-07-01 Laboratoires Besins International Treatment of mastalgia with 4-hydroxy tamoxifen
JP4684655B2 (ja) * 2002-12-18 2011-05-18 ラボラトワール ブザン アンテルナスィヨナル ４−ヒドロキシタモキシフェンによる乳房密度低下
CA2519980C (en) * 2003-04-01 2012-04-10 Laboratoires Besins International Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
PL1694319T3 (pl) * 2003-12-15 2009-01-30 Besins Healthcare Lu Sarl Zastosowanie 4-hydroksytamoksyfenu do wytwarzania leku do leczenia ginekomastii

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4919937A (en) * 1984-01-20 1990-04-24 Mauvais Jarvis Pierre Percutaneous administration of tamoxifen
US4973755A (en) * 1987-04-21 1990-11-27 Heumann Pharma Gmbh & Co. Stable solvent adducts of Z-1-(p-β-dimethylaminoethoxy-phenyl)-1-(p-hydroxyphenyl)-2-phenyl-but-1-ene
RU2207844C2 (ru) * 1998-12-23 2003-07-10 Идеа Аг. УСОВЕРШЕНСТВОВАННЫЙ ПРЕПАРАТ ДЛЯ МЕСТНОГО НЕИНВАЗИВНОГО ПРИМЕНЕНИЯ in vivo
RU2188000C1 (ru) * 2001-09-27 2002-08-27 Нестерук Владимир Викторович Лекарственное средство на основе тамоксифена
US20030087885A1 (en) * 2001-11-07 2003-05-08 Valerie Masini-Eteve Pharmaceutical composition in the form of a gel or a solution based on dihydrotestosterone, process for preparing it and uses thereof

Also Published As

Publication number Publication date
NO20064609L (no) 2006-10-11
NZ549817A (en) 2010-06-25
ATE391499T1 (de) 2008-04-15
WO2005092309A1 (en) 2005-10-06
HK1096595A1 (en) 2007-06-08
CA2559748A1 (en) 2005-10-06
CA2559748C (en) 2013-05-28
CN1946387A (zh) 2007-04-11
EP1748770B1 (en) 2008-04-09
DK1748770T3 (da) 2008-08-04
EP1748770A1 (en) 2007-02-07
PL1748770T3 (pl) 2008-09-30
AU2005227072B2 (en) 2010-08-19
AU2005227072A1 (en) 2005-10-06
JP2007535505A (ja) 2007-12-06
NO336767B1 (no) 2015-10-26
MXPA06010914A (es) 2006-12-15
DE602005005986D1 (de) 2008-05-21
RU2006137280A (ru) 2008-04-27
ES2306111T3 (es) 2008-11-01
DE602005005986T2 (de) 2009-06-04
JP5072588B2 (ja) 2012-11-14
PT1748770E (pt) 2008-07-16
CN1946387B (zh) 2011-08-31

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Effective date: 20140910

PD4A Correction of name of patent owner