PT1748770E - Tratamento e prevenção de doença benigna da mama com 4-hidroxi-tamoxifeno - Google Patents
Tratamento e prevenção de doença benigna da mama com 4-hidroxi-tamoxifeno Download PDFInfo
- Publication number
- PT1748770E PT1748770E PT05716433T PT05716433T PT1748770E PT 1748770 E PT1748770 E PT 1748770E PT 05716433 T PT05716433 T PT 05716433T PT 05716433 T PT05716433 T PT 05716433T PT 1748770 E PT1748770 E PT 1748770E
- Authority
- PT
- Portugal
- Prior art keywords
- benign breast
- hydroxy tamoxifen
- breast disease
- prevention
- treatment
- Prior art date
Links
- DODQJNMQWMSYGS-QPLCGJKRSA-N 4-[(z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1-phenylbut-1-en-2-yl]phenol Chemical compound C=1C=C(O)C=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 DODQJNMQWMSYGS-QPLCGJKRSA-N 0.000 title abstract 3
- 208000011803 breast fibrocystic disease Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 2
- 210000000481 breast Anatomy 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04290761A EP1579856A1 (en) | 2004-03-22 | 2004-03-22 | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US10/805,528 US7507769B2 (en) | 2004-03-22 | 2004-03-22 | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1748770E true PT1748770E (pt) | 2008-07-16 |
Family
ID=34961912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05716433T PT1748770E (pt) | 2004-03-22 | 2005-03-10 | Tratamento e prevenção de doença benigna da mama com 4-hidroxi-tamoxifeno |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1748770B1 (https=) |
| JP (1) | JP5072588B2 (https=) |
| CN (1) | CN1946387B (https=) |
| AT (1) | ATE391499T1 (https=) |
| AU (1) | AU2005227072B2 (https=) |
| CA (1) | CA2559748C (https=) |
| DE (1) | DE602005005986T2 (https=) |
| DK (1) | DK1748770T3 (https=) |
| ES (1) | ES2306111T3 (https=) |
| MX (1) | MXPA06010914A (https=) |
| NO (1) | NO336767B1 (https=) |
| NZ (1) | NZ549817A (https=) |
| PL (1) | PL1748770T3 (https=) |
| PT (1) | PT1748770E (https=) |
| RU (1) | RU2357726C2 (https=) |
| WO (1) | WO2005092309A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1799201B1 (en) * | 2004-10-14 | 2008-11-26 | Laboratoires Besins International | 4-hydroxy tamoxifen gel formulations |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2515041A1 (fr) * | 1981-10-26 | 1983-04-29 | Besins Jean | Medicament a base de progesterone pour le traitement des affections mammaires |
| FR2558373B1 (fr) * | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| ATE80152T1 (de) * | 1987-04-21 | 1992-09-15 | Heumann Pharma Gmbh & Co | Stabile loesungsmitteladdukte von z-1-(p-betadimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl) 2-phenylbut-1-en. |
| DE4407742C1 (de) * | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| DE69825495T2 (de) * | 1998-12-23 | 2005-07-28 | Idea Ag | Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo |
| RU2188000C1 (ru) * | 2001-09-27 | 2002-08-27 | Нестерук Владимир Викторович | Лекарственное средство на основе тамоксифена |
| PT1317921E (pt) * | 2001-12-07 | 2009-11-06 | Besins Mfg Belgium | Composição farmacêutica sob a forma de gel ou de solução à base de di-hidrotestosterona, seu processo de preparação e suas utilizações |
| WO2004054557A2 (en) * | 2002-12-18 | 2004-07-01 | Laboratoires Besins International | Treatment of mastalgia with 4-hydroxy tamoxifen |
| JP4684655B2 (ja) * | 2002-12-18 | 2011-05-18 | ラボラトワール ブザン アンテルナスィヨナル | ４−ヒドロキシタモキシフェンによる乳房密度低下 |
| CA2519980C (en) * | 2003-04-01 | 2012-04-10 | Laboratoires Besins International | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| PL1694319T3 (pl) * | 2003-12-15 | 2009-01-30 | Besins Healthcare Lu Sarl | Zastosowanie 4-hydroksytamoksyfenu do wytwarzania leku do leczenia ginekomastii |
-
2005
- 2005-03-10 CN CN2005800091724A patent/CN1946387B/zh not_active Expired - Lifetime
- 2005-03-10 DE DE602005005986T patent/DE602005005986T2/de not_active Expired - Lifetime
- 2005-03-10 ES ES05716433T patent/ES2306111T3/es not_active Expired - Lifetime
- 2005-03-10 RU RU2006137280/15A patent/RU2357726C2/ru active
- 2005-03-10 AU AU2005227072A patent/AU2005227072B2/en not_active Expired
- 2005-03-10 NZ NZ549817A patent/NZ549817A/en not_active IP Right Cessation
- 2005-03-10 PL PL05716433T patent/PL1748770T3/pl unknown
- 2005-03-10 JP JP2007504377A patent/JP5072588B2/ja not_active Expired - Lifetime
- 2005-03-10 MX MXPA06010914A patent/MXPA06010914A/es active IP Right Grant
- 2005-03-10 PT PT05716433T patent/PT1748770E/pt unknown
- 2005-03-10 CA CA2559748A patent/CA2559748C/en not_active Expired - Lifetime
- 2005-03-10 AT AT05716433T patent/ATE391499T1/de active
- 2005-03-10 WO PCT/EP2005/003286 patent/WO2005092309A1/en not_active Ceased
- 2005-03-10 EP EP05716433A patent/EP1748770B1/en not_active Expired - Lifetime
- 2005-03-10 DK DK05716433T patent/DK1748770T3/da active
-
2006
- 2006-10-11 NO NO20064609A patent/NO336767B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20064609L (no) | 2006-10-11 |
| NZ549817A (en) | 2010-06-25 |
| ATE391499T1 (de) | 2008-04-15 |
| WO2005092309A1 (en) | 2005-10-06 |
| HK1096595A1 (en) | 2007-06-08 |
| CA2559748A1 (en) | 2005-10-06 |
| CA2559748C (en) | 2013-05-28 |
| CN1946387A (zh) | 2007-04-11 |
| EP1748770B1 (en) | 2008-04-09 |
| DK1748770T3 (da) | 2008-08-04 |
| EP1748770A1 (en) | 2007-02-07 |
| PL1748770T3 (pl) | 2008-09-30 |
| AU2005227072B2 (en) | 2010-08-19 |
| AU2005227072A1 (en) | 2005-10-06 |
| JP2007535505A (ja) | 2007-12-06 |
| NO336767B1 (no) | 2015-10-26 |
| RU2357726C2 (ru) | 2009-06-10 |
| MXPA06010914A (es) | 2006-12-15 |
| DE602005005986D1 (de) | 2008-05-21 |
| RU2006137280A (ru) | 2008-04-27 |
| ES2306111T3 (es) | 2008-11-01 |
| DE602005005986T2 (de) | 2009-06-04 |
| JP5072588B2 (ja) | 2012-11-14 |
| CN1946387B (zh) | 2011-08-31 |
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