ATE391499T1 - 4-hydroxytamoxifen zur behandlung und prophylaxe von benignen brusterkrankungen - Google Patents

4-hydroxytamoxifen zur behandlung und prophylaxe von benignen brusterkrankungen

Info

Publication number
ATE391499T1
ATE391499T1 AT05716433T AT05716433T ATE391499T1 AT E391499 T1 ATE391499 T1 AT E391499T1 AT 05716433 T AT05716433 T AT 05716433T AT 05716433 T AT05716433 T AT 05716433T AT E391499 T1 ATE391499 T1 AT E391499T1
Authority
AT
Austria
Prior art keywords
benigon
hydroxytamoxifen
prophylaxis
treatment
benign breast
Prior art date
Application number
AT05716433T
Other languages
English (en)
Inventor
Nestour Elisabeth Le
Original Assignee
Besins Int Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04290761A external-priority patent/EP1579856A1/de
Priority claimed from US10/805,528 external-priority patent/US7507769B2/en
Application filed by Besins Int Lab filed Critical Besins Int Lab
Application granted granted Critical
Publication of ATE391499T1 publication Critical patent/ATE391499T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05716433T 2004-03-22 2005-03-10 4-hydroxytamoxifen zur behandlung und prophylaxe von benignen brusterkrankungen ATE391499T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04290761A EP1579856A1 (de) 2004-03-22 2004-03-22 4-Hydroxytamoxifen zur Behandlung von benignen Brusterkrankungen
US10/805,528 US7507769B2 (en) 2004-03-22 2004-03-22 Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen

Publications (1)

Publication Number Publication Date
ATE391499T1 true ATE391499T1 (de) 2008-04-15

Family

ID=34961912

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05716433T ATE391499T1 (de) 2004-03-22 2005-03-10 4-hydroxytamoxifen zur behandlung und prophylaxe von benignen brusterkrankungen

Country Status (16)

Country Link
EP (1) EP1748770B1 (de)
JP (1) JP5072588B2 (de)
CN (1) CN1946387B (de)
AT (1) ATE391499T1 (de)
AU (1) AU2005227072B2 (de)
CA (1) CA2559748C (de)
DE (1) DE602005005986T2 (de)
DK (1) DK1748770T3 (de)
ES (1) ES2306111T3 (de)
MX (1) MXPA06010914A (de)
NO (1) NO336767B1 (de)
NZ (1) NZ549817A (de)
PL (1) PL1748770T3 (de)
PT (1) PT1748770E (de)
RU (1) RU2357726C2 (de)
WO (1) WO2005092309A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007004371A (es) * 2004-10-14 2007-06-07 Besins Int Lab Formulaciones de 4-hidroxitamoxifen en gel.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515041A1 (fr) * 1981-10-26 1983-04-29 Besins Jean Medicament a base de progesterone pour le traitement des affections mammaires
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
EP0287690B1 (de) * 1987-04-21 1992-09-02 HEUMANN PHARMA GMBH & CO Stabile Lösungsmitteladdukte von Z-1-(p-beta-Dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-en
DE4407742C1 (de) * 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
ATE272391T1 (de) * 1998-12-23 2004-08-15 Idea Ag Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo
RU2188000C1 (ru) * 2001-09-27 2002-08-27 Нестерук Владимир Викторович Лекарственное средство на основе тамоксифена
DK1317921T3 (da) * 2001-12-07 2009-12-21 Besins Mfg Belgium Farmaceutisk sammensætning i form af en gel eller oplösning med dihydrotestosteron, fremgangsmåde til fremstilling og anvendelser heraf
EP1572178B1 (de) * 2002-12-18 2006-05-03 Laboratoires Besins International Behandlung von mastalgie mit4-hydroxy-tamoxifen
EP1572171B1 (de) * 2002-12-18 2009-04-22 Laboratoires Besins International Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen
NZ542499A (en) * 2003-04-01 2008-10-31 Besins Int Lab Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
CA2549824C (en) * 2003-12-15 2012-03-13 Laboratoires Besins International Use of 4-hydroxytamoxifen for the preparation of a medicament for the treatment of gynecomastia

Also Published As

Publication number Publication date
AU2005227072A1 (en) 2005-10-06
DE602005005986T2 (de) 2009-06-04
DE602005005986D1 (de) 2008-05-21
MXPA06010914A (es) 2006-12-15
RU2357726C2 (ru) 2009-06-10
CA2559748A1 (en) 2005-10-06
ES2306111T3 (es) 2008-11-01
AU2005227072B2 (en) 2010-08-19
HK1096595A1 (en) 2007-06-08
NO336767B1 (no) 2015-10-26
PT1748770E (pt) 2008-07-16
JP5072588B2 (ja) 2012-11-14
NZ549817A (en) 2010-06-25
EP1748770B1 (de) 2008-04-09
WO2005092309A1 (en) 2005-10-06
CN1946387B (zh) 2011-08-31
JP2007535505A (ja) 2007-12-06
NO20064609L (no) 2006-10-11
DK1748770T3 (da) 2008-08-04
CN1946387A (zh) 2007-04-11
EP1748770A1 (de) 2007-02-07
PL1748770T3 (pl) 2008-09-30
CA2559748C (en) 2013-05-28
RU2006137280A (ru) 2008-04-27

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