RU2329049C2 - Профилактическое и терапевтическое применение гидроксистероидов - Google Patents

Профилактическое и терапевтическое применение гидроксистероидов Download PDF

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Publication number
RU2329049C2
RU2329049C2 RU2004104362/15A RU2004104362A RU2329049C2 RU 2329049 C2 RU2329049 C2 RU 2329049C2 RU 2004104362/15 A RU2004104362/15 A RU 2004104362/15A RU 2004104362 A RU2004104362 A RU 2004104362A RU 2329049 C2 RU2329049 C2 RU 2329049C2
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Russia
Prior art keywords
group
use according
damage
groups
hydroxy
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RU2004104362/15A
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English (en)
Russian (ru)
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RU2004104362A (ru
Inventor
Эрнст ВЮЛФЕРТ (BE)
Эрнст ВЮЛФЕРТ
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Хантэр-Флеминг Лимитед
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2004104362/15A 2001-08-14 2002-08-13 Профилактическое и терапевтическое применение гидроксистероидов RU2329049C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0119810A GB2378898A (en) 2001-08-14 2001-08-14 Prophylactic and therapeutic use of hydroxysteroids
GB0119810.0 2001-08-14

Publications (2)

Publication Number Publication Date
RU2004104362A RU2004104362A (ru) 2005-05-10
RU2329049C2 true RU2329049C2 (ru) 2008-07-20

Family

ID=9920376

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004104362/15A RU2329049C2 (ru) 2001-08-14 2002-08-13 Профилактическое и терапевтическое применение гидроксистероидов

Country Status (19)

Country Link
US (1) US8148355B2 (enExample)
EP (1) EP1416937B1 (enExample)
JP (1) JP4541698B2 (enExample)
KR (1) KR100895281B1 (enExample)
CN (1) CN1700920B (enExample)
AT (1) ATE429919T1 (enExample)
AU (1) AU2002321472B2 (enExample)
CA (1) CA2457050C (enExample)
CY (1) CY1109233T1 (enExample)
DE (1) DE60232154D1 (enExample)
DK (1) DK1416937T3 (enExample)
ES (1) ES2324859T3 (enExample)
GB (1) GB2378898A (enExample)
IL (2) IL160362A0 (enExample)
NO (1) NO334819B1 (enExample)
NZ (1) NZ531100A (enExample)
PT (1) PT1416937E (enExample)
RU (1) RU2329049C2 (enExample)
WO (1) WO2003015791A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2448712C2 (ru) * 2006-11-30 2012-04-27 Хантер-Флеминг Лимитед Модуляция путей обмена простагландина/циклооксигеназы

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070231373A1 (en) * 2004-04-28 2007-10-04 Hunter-Fleming Limited Transdermal Steriod for Formulation
US7910755B2 (en) 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
JP2010511028A (ja) * 2006-11-30 2010-04-08 ハンター−フレミング・リミテッド プロスタグランジン/シクロオキシゲナーゼの代謝経路の調節
EP2653163A1 (en) * 2012-04-19 2013-10-23 Université de Liège Estrogenic components for use in the treatment of neurological disorders
CN105078954A (zh) * 2015-08-20 2015-11-25 南京华宽信息咨询中心 一种治疗急性肾衰药物及其应用
CN105168197A (zh) * 2015-08-22 2015-12-23 南京华宽信息咨询中心 一种治疗肾功能不全药物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792759A (en) * 1995-06-23 1998-08-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same
WO1999011271A1 (en) * 1997-08-29 1999-03-11 Dalhousie University Use of polycyclic steroid compounds for the manufacture of a medicament for the treatment of cystic kidney diseases, vascular infarction, uremia and related conditions
WO1999052532A1 (en) * 1998-04-14 1999-10-21 Pharmadigm, Inc. Method for reducing central nervous system impairment
RU2171677C1 (ru) * 2000-07-31 2001-08-10 Саратовский научно-исследовательский институт травматологии и ортопедии Способ лечения больных с повреждениями позвоночника и спинного мозга

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686438A (en) * 1993-03-09 1997-11-11 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5846963A (en) * 1995-06-07 1998-12-08 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
US5977095A (en) * 1993-03-09 1999-11-02 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and respiratory distress syndrome
US5753640A (en) * 1995-06-07 1998-05-19 University Of Utah Research Foundation Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
DE69434149T2 (de) * 1993-03-09 2006-07-20 University Of Utah Research Foundation, Salt Lake City Verwendung von dhea oder dessen derivate zur herstellung eines medikaments zur vorbeugung von progressiver gewebe-nekrose, reperfusionsschädigung, bakterieller translokation und vom atemnotsyndrom bei erwachsenen
GB0003524D0 (en) * 2000-02-15 2000-04-05 Btg Int Ltd Cytoprotective steroids (II)
GB2363984A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792759A (en) * 1995-06-23 1998-08-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same
WO1999011271A1 (en) * 1997-08-29 1999-03-11 Dalhousie University Use of polycyclic steroid compounds for the manufacture of a medicament for the treatment of cystic kidney diseases, vascular infarction, uremia and related conditions
WO1999052532A1 (en) * 1998-04-14 1999-10-21 Pharmadigm, Inc. Method for reducing central nervous system impairment
RU2171677C1 (ru) * 2000-07-31 2001-08-10 Саратовский научно-исследовательский институт травматологии и ортопедии Способ лечения больных с повреждениями позвоночника и спинного мозга

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
БЕЛИКОВ В.Г. Фармацевтическая химия. - М.: Высшая школа, 1993 г., т.1, с.43-47. ГЕОРГИЕВСКИЙ В.П. и КОНЕВ Ф.А. Технология и стандартизация лекарств. ООО «РИРЕГ». - Харьков, 1996 г. с.5-8. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2448712C2 (ru) * 2006-11-30 2012-04-27 Хантер-Флеминг Лимитед Модуляция путей обмена простагландина/циклооксигеназы

Also Published As

Publication number Publication date
RU2004104362A (ru) 2005-05-10
EP1416937B1 (en) 2009-04-29
DK1416937T3 (da) 2009-08-24
GB0119810D0 (en) 2001-10-10
WO2003015791A1 (en) 2003-02-27
ATE429919T1 (de) 2009-05-15
JP2005506321A (ja) 2005-03-03
CN1700920B (zh) 2012-05-30
HK1065703A1 (en) 2005-03-04
JP4541698B2 (ja) 2010-09-08
EP1416937A1 (en) 2004-05-12
KR100895281B1 (ko) 2009-04-29
CA2457050C (en) 2010-10-12
IL160362A0 (en) 2004-07-25
IL160362A (en) 2011-10-31
US20040248868A1 (en) 2004-12-09
CN1700920A (zh) 2005-11-23
ES2324859T3 (es) 2009-08-18
CY1109233T1 (el) 2014-07-02
NZ531100A (en) 2006-02-24
NO20041057L (no) 2004-03-12
NO334819B1 (no) 2014-06-10
KR20040041577A (ko) 2004-05-17
PT1416937E (pt) 2009-07-24
GB2378898A (en) 2003-02-26
US8148355B2 (en) 2012-04-03
CA2457050A1 (en) 2003-02-27
DE60232154D1 (de) 2009-06-10
AU2002321472B2 (en) 2007-11-08

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Effective date: 20160814